Cholera Vaccines Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Type, By Product, By Distribution Channel, By Region & Competition, 2021-2031F

Description

The global cholera vaccines market is projected to expand significantly, growing from USD 97.32 Million in 2025 to USD 166.11 Million by 2031 at a 9.32% CAGR. These biological preparations, primarily oral formulations, induce immunity against the Vibrio cholerae bacterium. The market is propelled by the intensifying frequency of cholera outbreaks, largely attributed to climate change phenomena such as severe flooding and droughts that compromise water and sanitation infrastructure. The escalation of humanitarian crises and population displacement further necessitates rigorous mass vaccination campaigns to mitigate morbidity in high-risk zones, with over 40 million oral cholera vaccine doses allocated globally in 2025 to address surging outbreaks and humanitarian emergencies, according to the International Coordinating Group on Vaccine Provision.

Market Overview
Forecast Period	2027-2031
Market Size 2025	USD 97.32 MIllion
Market Size 2031	USD 166.11 MIllion
CAGR 2026-2031	9.32%
Fastest Growing Segment	Shanchol
Largest Market	Asia Pacific

Market Driver

The resurgence of cholera outbreaks in endemic regions, heavily influenced by climate change-induced events like severe floods and cyclones contaminating water, serves as the primary catalyst driving the market's urgent expansion. This escalation, which led to 409,222 cholera cases and over 4,700 deaths between January and August 2025 as reported by the WHO, has rapidly depleted existing stockpiles, creating an immediate need for replenishment and distribution. Additionally, advancements in vaccine formulation and the expansion of manufacturing infrastructure are reshaping supply dynamics; pharmaceutical companies and global alliances are investing in high-capacity production facilities and streamlining regulatory approvals, exemplified by Bharat Biotech's plan for 200 million doses annually and EuBiologics Co., Ltd's commitment to supply 72 million doses to UNICEF in 2025.

Market Challenge

Despite this robust demand and production efforts, the market faces a significant barrier: insufficient global production capacity relative to immediate public health requirements. This manufacturing bottleneck creates a hard ceiling on market volume, preventing the industry from capitalizing on demand, resulting in severe stockpile shortages, forced dose rationing strategies, delayed response times in endemic regions, and restricted geographical expansion. This persistent gap, where requests for 13.9 million doses in Q1 2025 alone rapidly depleted stock, remains the primary restraint hindering broader market expansion and timely disease elimination efforts.

Market Trends

In parallel, two key trends are influencing the market: the growth in the private travel market and prophylactic vaccination demand, offering a lucrative segment with higher price points from international tourists to endemic zones, as shown by Valneva SE's Dukoral vaccine sales growing to €17.4 million in H1 2025. Simultaneously, there's a diversification of the global manufacturing and supply base, shifting production geography to reduce reliance on Asian incumbents and enhance regional health security. This involves funding technology transfers to local manufacturers, particularly in Africa, to decentralize the supply chain and ensure indigenous end-to-end capabilities, such as Biovac in South Africa commencing Phase 1 clinical trials for its locally manufactured oral cholera vaccine in October 2025.

Key Market Players

Valneva SE
Sanofi S.A.
Emergent BioSolutions Inc.
EuBiologics Co., Ltd.
Shantha Biotechnics Limited
Hilleman Laboratories Singapore Pte Ltd
Astellas Pharma Inc.
Incepta Pharmaceuticals Ltd.
Bharat Biotech Ltd.
Takeda Pharmaceutical Company Limited

Report Scope

In this report, the Global Cholera Vaccines Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

Cholera Vaccines Market, By Type

Whole cell V. Cholerae O1 Recombinant With B-Subunit
Killed Oral O1 & O139

Cholera Vaccines Market, By Product

Vaxchora
Dukoral
Shanchol
Others

Cholera Vaccines Market, By Distribution Channel

Hospital Pharmacy
Retail Pharmacy
Others

Cholera Vaccines Market, By Region

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Cholera Vaccines Market.

Available Customizations:

Global Cholera Vaccines Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global Cholera Vaccines Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Type (Whole cell V. Cholerae O1 Recombinant With B-Subunit, Killed Oral O1 & O139)
- 5.2.2. By Product (Vaxchora, Dukoral, Shanchol, Others)
- 5.2.3. By Distribution Channel (Hospital Pharmacy, Retail Pharmacy, Others)
- 5.2.4. By Region
- 5.2.5. By Company (2025)
5.3. Market Map

6. North America Cholera Vaccines Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Type
- 6.2.2. By Product
- 6.2.3. By Distribution Channel
- 6.2.4. By Country
6.3. North America: Country Analysis
- 6.3.1. United States Cholera Vaccines Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Type
    - 6.3.1.2.2. By Product
    - 6.3.1.2.3. By Distribution Channel
- 6.3.2. Canada Cholera Vaccines Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Type
    - 6.3.2.2.2. By Product
    - 6.3.2.2.3. By Distribution Channel
- 6.3.3. Mexico Cholera Vaccines Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Type
    - 6.3.3.2.2. By Product
    - 6.3.3.2.3. By Distribution Channel

7. Europe Cholera Vaccines Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Type
- 7.2.2. By Product
- 7.2.3. By Distribution Channel
- 7.2.4. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany Cholera Vaccines Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Type
    - 7.3.1.2.2. By Product
    - 7.3.1.2.3. By Distribution Channel
- 7.3.2. France Cholera Vaccines Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Type
    - 7.3.2.2.2. By Product
    - 7.3.2.2.3. By Distribution Channel
- 7.3.3. United Kingdom Cholera Vaccines Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Type
    - 7.3.3.2.2. By Product
    - 7.3.3.2.3. By Distribution Channel
- 7.3.4. Italy Cholera Vaccines Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Type
    - 7.3.4.2.2. By Product
    - 7.3.4.2.3. By Distribution Channel
- 7.3.5. Spain Cholera Vaccines Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Type
    - 7.3.5.2.2. By Product
    - 7.3.5.2.3. By Distribution Channel

8. Asia Pacific Cholera Vaccines Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Type
- 8.2.2. By Product
- 8.2.3. By Distribution Channel
- 8.2.4. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China Cholera Vaccines Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Type
    - 8.3.1.2.2. By Product
    - 8.3.1.2.3. By Distribution Channel
- 8.3.2. India Cholera Vaccines Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Type
    - 8.3.2.2.2. By Product
    - 8.3.2.2.3. By Distribution Channel
- 8.3.3. Japan Cholera Vaccines Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Type
    - 8.3.3.2.2. By Product
    - 8.3.3.2.3. By Distribution Channel
- 8.3.4. South Korea Cholera Vaccines Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Type
    - 8.3.4.2.2. By Product
    - 8.3.4.2.3. By Distribution Channel
- 8.3.5. Australia Cholera Vaccines Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Type
    - 8.3.5.2.2. By Product
    - 8.3.5.2.3. By Distribution Channel

9. Middle East & Africa Cholera Vaccines Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Type
- 9.2.2. By Product
- 9.2.3. By Distribution Channel
- 9.2.4. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia Cholera Vaccines Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Type
    - 9.3.1.2.2. By Product
    - 9.3.1.2.3. By Distribution Channel
- 9.3.2. UAE Cholera Vaccines Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Type
    - 9.3.2.2.2. By Product
    - 9.3.2.2.3. By Distribution Channel
- 9.3.3. South Africa Cholera Vaccines Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Type
    - 9.3.3.2.2. By Product
    - 9.3.3.2.3. By Distribution Channel

10. South America Cholera Vaccines Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Type
- 10.2.2. By Product
- 10.2.3. By Distribution Channel
- 10.2.4. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil Cholera Vaccines Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Type
    - 10.3.1.2.2. By Product
    - 10.3.1.2.3. By Distribution Channel
- 10.3.2. Colombia Cholera Vaccines Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Type
    - 10.3.2.2.2. By Product
    - 10.3.2.2.3. By Distribution Channel
- 10.3.3. Argentina Cholera Vaccines Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Type
    - 10.3.3.2.2. By Product
    - 10.3.3.2.3. By Distribution Channel

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global Cholera Vaccines Market: SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Valneva SE
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. Sanofi S.A.
15.3. Emergent BioSolutions Inc.
15.4. EuBiologics Co., Ltd.
15.5. Shantha Biotechnics Limited
15.6. Hilleman Laboratories Singapore Pte Ltd
15.7. Astellas Pharma Inc.
15.8. Incepta Pharmaceuticals Ltd.
15.9. Bharat Biotech Ltd.
15.10. Takeda Pharmaceutical Company Limited