NGS Sample Preparation Market: Current Analysis and Forecast (2021-2027)

The global NGS Sample Preparation Market is anticipated to grow with an elevated CAGR of around 15% over the forecast period (2021-2027). Next-generation sequencing (NGS) is a technology used to determine the RNA or DNA sequence to study genetic variation associated with various types of diseases or other biological phenomena. With advancements in sequencing technologies and constant innovations, the protocols for sample preparation have been standardized.

The NGS sample preparation market has been growing on account of various factors including the growing emphasis on NGS-based diagnostics and surging incidences of cancer across the globe. For instance, the number of cancer cases in the US will increase 49% each year, from 1,534,500 in 2015 to 2,286,300 in 2050, with the largest percentage increase among adults aged ≥75 years, as per the predictions by CDC. This exponential increase in cancer prevalence has created a buzz among biotechnology and pharmaceutical companies for investing in the development of effective and reliable diagnostic tools based on the NGS.

Furthermore, promulgating strategic alliances among industry players and growing advancement in NGS technologies which can be used in different areas of biomedical, basic research and agriculture are other factors that are significantly driving the NGS sample preparation market globally. For example, in June 2020, 10x Genomics, Inc. and Merck collaborated for providing impactful linking of two innovative technologies: single-cell transcriptomics and pooled CRISPR screening to the researchers which will provide more detailed information to them for understanding the relationship between specific genes and disease.

Becton, Dickinson and Company, Thermo Fisher Scientific, QIAGEN N.V., Agilent Technologies, Inc., F. Hoffmann-La Roche Ltd., Integrated DNA Technologies, Inc., Beckman Coulter, Pacific Biosciences of California, Promega Corporation, are some of the prominent players operating in the NGS sample preparation market. Several M&As along with partnerships have been undertaken by these players to facilitate customers with NGS sample preparation products.

Insights Presented in the Report

"Amongst Product, reagents & consumables segment holds the major share"

Based on product, the NGS sample preparation market is segmented into workstations and reagents & consumables. In 2020, the reagents & consumables segment accounted for a significant market share, and it is projected that it will exhibit considerable growth during the forecast period owing to the rising number of sequencing procedures and the launch of new and advanced consumables. In addition, the growing adoption of next-generation sequencing because of the availability of research grants, decreasing cost of sequencing, and increasing application of NGS in various fields are also contributing to the growth of this segment.

"Amongst Library Preparation, DNA segment holds the major share"

Based on library preparation, the NGS sample preparation market is divided into DNA, RNA, target enrichment, and quality control. The DNA segment accounted for a significant market share in 2020 and it is estimated that it will exhibit considerable growth during the forecast period as DNA is most commonly used for sequence profiling in the next-generation sequencing procedures. Library preparation allows DNA to adhere to the sequencing flowcell and allows the sample to be identified.

"Amongst Technology, sequencing by synthesis segment holds the major share"

Based on technology, the market is fragmented into sequencing by synthesis, ion semiconductor sequencing, nanopore sequencing, and other technologies. In 2020, the sequencing by synthesis (SBS) technology segment grabbed a considerable market share, and it is expected to grow at a significant CAGR during the forecast. This segment is expected to grow as Illumina sequencing technology, sequencing by synthesis (SBS) is widely adopted NGS technology across the world and responsible for generating more than 90% of the world's sequencing data. Further, the increase in the availability of NGS platforms based on SBS is driving the growth of the segment.

"Amongst Application, disease diagnostics segment holds the major share"

Based on application, the NGS sample preparation market is divided into disease diagnostics, drug discovery, and agriculture and animal research. The disease diagnostics segment occupied the major share of the NGS sample preparation market in 2020 and it is expected to grow with substantial CAGR in the upcoming years. The growth of this segment is attributed to the growing prevalence of various diseases such as cancer, infectious, and other rare diseases. For instance, according to the World Health Organization, more than 13 million people die from infectious diseases each year. Further, in some developing countries, it leads to 1 in 2 deaths annually.

"Amongst End-Users, academic institutes and research centers segment holds the major share"

Based on end-users, the market is fragmented into academic institutes and research centers, hospitals & clinics, pharmaceutical & biotechnology companies, and other end-users. In 2020, the academic institutes & research centers segment grabbed a considerable market share, and it is expected to grow at a significant CAGR during the forecast. This is because of the increasing adoption of NGS in cancer research for identifying new cancer-related genes and to study modifications that may contribute to tumorigenesis. In addition, Promulgating strategic alliances between NGS market players and academic & research centers and the availability of funds for genomics R&D across the globe are also some of the major factors contributing to the growth of this segment.

"North America represents one of the largest markets of NGS sample preparation market"

For a better understanding of the market dynamics of the NGS sample preparation market, a detailed analysis was conducted for different regions across the globe including North America (U.S, Canada, and Rest of North America), Europe (Germany, France, Spain, United Kingdom, Italy, and Rest of Europe), Asia-Pacific (China, India, Australia, Japan, and Rest of APAC), Rest of World has been conducted. North America constitutes a major market for the NGS sample preparation market industry and generated revenue of USD XX Million in 2020 owing to strong healthcare infrastructure and growing adoption of advanced technological solutions in the healthcare industry in the region.

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