Global Pharmaceutical Gelatin Market Size By Type, By Application, By Source, By End-User, By Geographic Scope And Forecast

Pharmaceutical Gelatin Market Size And Forecast

Pharmaceutical Gelatin Market size was valued at USD 1.24 Billion in 2024 and is projected to reach USD 1.79 Billion by 2031, growing at a CAGR of 5.20% from 2024 to 2031.

Pharmaceutical gelatin, derived fr.om the partial hydrolysis of collagen obtained from animal skin, white connective tissues, and bones, is characterized by its high molecular weight, thermo-reversibility, biocompatibility, and water solubility. These properties make it a crucial excipient in the pharmaceutical industry.

Gelatin is predominantly used in the manufacture of hard capsules and soft gels, serving as a protective barrier that shields sensitive ingredients, such as fish oil, from oxygen, light, contamination, and microbiological growth.

Its applications extend to binding agents in tablet formulations, stabilizers in vaccines, and other vital uses in pharmaceutical products.

Approximately 90% of gelatin produced for pharmaceutical purposes is utilized in creating commonly prescribed dose forms, including softgels, hard capsules, and tablets.

The pharmaceutical industry relies heavily on gelatin due to its ability to enhance drug stability, effectiveness, and bioavailability. Pharmaceutical gelatin helps encapsulate and protect active pharmaceutical ingredients and plays a critical role in developing film-coated and effervescent tablets.

The production of gelatin involves the hydrolysis of collagen, which is carefully controlled to ensure the final product meets stringent pharma-medical grade standards.

Global Pharmaceutical Gelatin Market Dynamics

The key market dynamics that are shaping the global pharmaceutical gelatin market include:

Key Market Drivers

Biomedical and Cosmetic: The growing use of gelatin in biomedical and cosmetic applications, including wound healing, wound dressing, tissue engineering, gene therapy, bone substitutes, and implants. Gelatin's versatile properties make it a valuable component in these areas, providing essential functions such as tissue regeneration and drug delivery.

Increasing Demand for Pharmaceutical Grade: The rising demand for pharmaceutical-grade gelatin is also a significant market driver. This increase is attributed to the escalating prevalence of chronic diseases such as diabetes, cancer, and cardiovascular conditions, which require ongoing medication and sophisticated drug formulations. Pharmaceutical gelatin is crucial in these formulations, particularly in sustained-release and soft gel capsules, which offer better bioavailability and are easier to swallow compared to traditional tablets. The shift towards soft gel capsules, driven by their consumer-friendly characteristics, is further fueling the demand for pharmaceutical gelatin.

Regenerative Medicine: The advancements in gelatin manufacturing technologies are enhancing the efficiency and cost-effectiveness of production processes, thereby supporting market growth. The increasing application of gelatin in regenerative medicine and tissue engineering is another growth catalyst, as these fields expand and demand more advanced materials for therapeutic applications. Gelatin's role as a key component in these areas highlights its importance in the pharmaceutical industry.

Fish Gelatin in Immunological: The use of fish-derived gelatin is also gaining traction, offering several advantages over traditional sources. Fish gelatin is immunologically safe, reduces the risk of transmitting diseases such as bovine spongiform encephalopathy and foot-and-mouth disease, and provides environmental and economic benefits. These factors contribute to the growing preference for fish gelatin, driving its market share within the pharmaceutical sector.

Popularity for Fortified Gummies: The surge in demand for fortified gummies, which serve as alternative delivery systems for vitamins and minerals, is also contributing to the growth of the pharmaceutical gelatin market. Gelatin's properties, such as its natural origin, biocompatibility, thermo-reversibility, and clean label-friendly characteristics, make it an ideal choice for these applications.

Key Challenges:

Presence of Substitute Components: The rising demand for plant-based alternatives, such as hydroxypropyl methylcellulose (HPMC) and modified starch, is influencing the pharmaceutical industry. These substitutes are increasingly used to produce vegetarian and vegan capsule shells. As the trend toward veganism and plant-based products grows, it poses a challenge to the market for animal-derived gelatin, potentially reducing its demand.

Concerns Regarding Animal-Derived Gelatin: Pharmaceutical gelatin is primarily sourced from animal by-products, such as bovine or porcine skin and bones. Cultural, religious, and ethical concerns surrounding the use of animal-derived ingredients are leading to increased scrutiny from consumers and regulatory bodies. These concerns are driving the search for alternative sources and substitutes for gelatin, which could limit market growth.

Availability of Alternatives: The availability of alternative excipients and formulation ingredients, including plant-based or synthetic polymers, presents a challenge to the pharmaceutical gelatin market. Manufacturers may opt for these alternatives to meet consumer preferences for vegetarian or vegan products or to address concerns related to animal-derived ingredients. This shift could impact the demand for traditional pharmaceutical gelatin.

Price Volatility of Raw Materials: The cost of raw materials used in gelatin production, such as animal hides, bones, and skins, can be volatile. Fluctuations in these prices, driven by supply and demand dynamics, environmental factors affecting livestock, and geopolitical issues, can affect production costs and profit margins. This price instability may pose a challenge to the pharmaceutical gelatin market.

Allergen Concerns: Although rare, gelatin allergies can occur in sensitive individuals, leading to adverse reactions from gelatin-containing pharmaceutical products. These allergen concerns can influence consumer choices, particularly among those with known allergies or those seeking alternative dosage forms. Such concerns could limit the adoption of pharmaceutical gelatin in certain patient populations.

Key Trends

Expansion in Emerging Markets: Emerging regions such as Asia-Pacific, the Middle East, Latin America, and Africa present substantial opportunities for the pharmaceutical gelatin market. Companies are increasingly focusing on these areas to tap into the growing demand for pharmaceutical-grade gelatin. For instance, major manufacturers are expanding their presence and production capabilities in countries like India and China. This trend is driven by the rising demand for gelatin in these economies, the availability of raw materials, and lower labor costs, which collectively provide significant growth prospects for the market.

Innovative Applications and Technologies: The pharmaceutical industry is witnessing a surge in innovative applications of gelatin, driven by advancements in technology. A notable example is etectRx, Inc.'s development of the ID-Cap System. This system integrates a hard gelatin capsule with an embedded ingestible wireless sensor and a wearable reader to monitor drug adherence. Such innovations are expanding the use of gelatin in advanced applications, such as smart capsules, and are likely to drive market growth by enhancing the functionality and appeal of gelatin-based products.

Focus on Gelatin Characterization: Advances in analytical techniques are improving the characterization of gelatin, leading to enhanced product quality and consistency. These advancements enable more precise control over gelatin's physical and chemical properties, ensuring that it meets the stringent requirements of pharmaceutical applications. Improved characterization supports the development of high-quality gelatin products that are critical for effective drug delivery and formulation.

Development of Modified Gelatins: Researchers are actively developing modified gelatins with specific properties tailored for targeted drug delivery and other specialized pharmaceutical applications. These modified gelatins are designed to meet specific performance criteria, such as controlled release or enhanced stability, which can significantly improve the efficacy of drug formulations and expand the range of applications for gelatin in the pharmaceutical industry.

Exploration of Plant-Based Alternatives: Although animal-derived gelatin remains dominant in the market, there is growing interest in plant-based alternatives. These alternatives are being developed to cater to dietary preferences and religious restrictions that preclude the use of animal-based products. The exploration of plant-based gelatin substitutes is driven by increasing consumer demand for vegan and vegetarian products and aims to provide solutions that align with ethical and cultural considerations.

Global Pharmaceutical Gelatin Market Regional Analysis

Here is a more detailed regional analysis of the global pharmaceutical gelatin market:

North America

North America substantially dominates the global pharmaceutical gelatin market and is expected to maintain its dominance throughout the forecast period driven by a combination of well-established pharmaceutical industries, robust research and development (R&D) activities, and a growing demand for pharmaceutical products.

As the largest market for pharmaceutical gelatin in North America, the United States benefits from a mature pharmaceutical industry and significant investments in R&D. The country's market growth is supported by the presence of leading gelatin manufacturers, increasing demand for nutraceuticals, and substantial funding for innovation in drug delivery systems.

The U.S. pharmaceutical sector's advanced infrastructure and high standards for product quality further drive the demand for pharmaceutical-grade gelatin, contributing to its dominance in the market.

Canada also holds a significant share of the North American pharmaceutical gelatin market. The growth in Canada is driven by an aging population, a rising prevalence of chronic diseases, and a growing need for advanced drug delivery solutions.

North America's stringent regulatory framework and high-quality standards have created a strong demand for pharmaceutical gelatin products. The region's focus on maintaining rigorous quality control and ensuring compliance with health regulations enhances the credibility and safety of pharmaceutical products.

The North American region's commitment to improving healthcare infrastructure and investing in pharmaceutical research supports the expansion of the pharmaceutical gelatin market.

Asia Pacific

The Asia-Pacific region is poised fastest growth in the global pharmaceutical gelatin market, driven by a convergence of factors that are creating a favorable environment for expansion.

The region's burgeoning pharmaceutical industry is a key driver, with both domestic and multinational companies making significant investments in research and development, manufacturing, and distribution. This growth is complemented by the easy availability of gelatin sources, which supports the increasing demand for this critical excipient.

The region's rising population and increasing life expectancy. The growing and aging demographic is leading to a higher demand for healthcare services and medications, which in turn fuels the need for pharmaceutical gelatin.

The region's robust pharmaceutical sector is fostering a dynamic market environment, where the demand for high-quality gelatin is rising in tandem with the industry's expansion.

Additionally, the increasing prevalence of chronic diseases such as diabetes, cardiovascular conditions, and cancer is contributing to the growing need for pharmaceutical products. Gelatin plays a crucial role in the formulation of various medications and supplements that address these chronic health issues.

As more individuals move into higher income brackets, there is a corresponding rise in healthcare expenditure, including spending on advanced pharmaceutical products that often incorporate gelatin.

Furthermore, favorable government initiatives are playing a significant role in supporting the pharmaceutical industry across the region. Many countries are implementing policies designed to boost the pharmaceutical sector, creating an advantageous environment for gelatin manufacturers.

Global Pharmaceutical Gelatin Market: Segmentation Analysis

The Global Pharmaceutical Gelatin Market is segmented based on Type, Application, Source, End-Use, And Geography.

Pharmaceutical Gelatin Market, By Type

Type A Gelatin

Type B Gelatin

Based on Type, the Global Pharmaceutical Gelatin Market is bifurcated into Type A Gelatin and Type B Gelatin. The Type B Gelatin segment dominates the global pharmaceutical gelatin market owing to the cost-effective production associated with the availability of raw materials, which helps to keep manufacturing costs down. Type B gelatin, in particular, offers increased gel storage stability compared to low-bloom gelatin, making it a preferred choice among industry players. This enhanced stability ensures that the soft gels maintain their quality and effectiveness over time, further bolstering the segment's growth and prominence in the market.

Pharmaceutical Gelatin Market, By Application

Hard Capsules

Softgel Capsules

Coatings

Parenteral Formulations

Based on Application, the Global Pharmaceutical Gelatin Market is bifurcated into Hard Capsules, and Softgel Capsules. The Soft Gel Capsules segment leads the Global Pharmaceutical Gelatin Market. Soft gel capsules are ideal for low-dose, lipid-soluble medications, offering uniform content distribution that enhances effectiveness and reliability. Their superior bioavailability improves the absorption of active ingredients, making them a preferred choice for various pharmaceutical applications.

Pharmaceutical Gelatin Market, By Source

Bovine Gelatin

Porcine Gelatin

Chicken Gelatin

Marine Gelatin

Based on the Source, the Global Pharmaceutical Gelatin Market is bifurcated into Bovine Gelatin, Porcine Gelatin, Chicken Gelatin, and Marine Gelatin. Porcine gelatin dominates the global pharmaceutical gelatin market. Its quick manufacturing cycle and cost-effective production processes contribute to its widespread use in the industry. Additionally, porcine-based gelatin is utilized in a variety of pharmaceutical applications, including as a stabilizer in vaccines and capsules. According to the National Health Service (NHS), porcine-derived gelatin plays a crucial role in maintaining the efficacy and safety of these products, especially during and after storage. These benefits drive the strong market share of porcine-sourced gelatin, making it a preferred choice for pharmaceutical formulations.

Pharmaceutical Gelatin Market, By End-User

Protein Bars and Powder

Food & Beverage

Confectionery

Dairy Products

Based on the End-User, the Global Pharmaceutical Gelatin Market is bifurcated into Protein Bars and Powder, Food & Beverage, Confectionery, and Dairy Products. The food and beverage segment currently leads the pharmaceutical gelatin market, thanks to its extensive applications and well-established consumer base. Gelatin's versatility in various food products, including confectioneries, dairy items, and desserts, solidifies its dominant position in this sector.

Pharmaceutical Gelatin Market, By Geography

North America

Europe

Asia Pacific

Rest of the world

Based on Geography, the Global Pharmaceutical Gelatin Market is classified into North America, Europe, Asia Pacific, and the Rest of the world. North America substantially dominates the global pharmaceutical gelatin market and is expected to maintain its dominance throughout the forecast period driven by a combination of well-established pharmaceutical industries, robust research and development (R&D) activities, and a growing demand for pharmaceutical products. As the largest market for pharmaceutical gelatin in North America, the United States benefits from a mature pharmaceutical industry and significant investments in R&D.

Key Players

The "Global Pharmaceutical Gelatin Market" study report will provide valuable insight with an emphasis on the global market. The major players in the market are Nitta Gelatin, PB Leiner GmbH, Tessenderlo Group, Weishardt Holding GmbH & Co. KG, Gelita AG, LAPI Gelatine, S.p.A., NiOx Gelatin, Croda International Plc, Eastman Chemical Company, Rousselot (ADM), I gelatine SA, Gelnex Pharmaceuticals, Bio-Gelatin GmbH, Gelatin Kelco Co.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with its product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

Global Pharmaceutical Gelatin Market Key Developments

• In 2022, in response to the food industry's need to meet European Union food standards, Lonza enhanced their Capsugel contribution with a white hard gelatin capsule that is titanium dioxide-free.
• In May 2021, Darling Ingredients Inc. announced the launch of X-Pure GelDAT Gelatin Desaminotyrosine for biomedical applications under the Rousselot brand, expanding its pure pharmaceutical-grade modified gelatin portfolio.
• In July 2022, Gelita established a biotech hub to develop proteins for pharmaceutical and medical applications, cosmetics, and nutrition.
• In May 2022, Capsugel expanded its titanium dioxide-free capsule line, adding white firm gelatin capsules that are free of titanium dioxide (TiO2). The novel titanium dioxide-free capsule is based on crystalline salts and delivers similar masking and whitening properties as titanium dioxide capsules. The product provides excellent light shielding and opacity.