PUBLISHER: Allied Market Research | PRODUCT CODE: 1344325
PUBLISHER: Allied Market Research | PRODUCT CODE: 1344325
The viral vector production market is likely to experience a significant growth rate of 18.8% from 2023-2032 owing to increasing market demand from diagnostic and biotech sector - Allied Market Research
Viral vectors are tools used in gene therapy and vaccine development to deliver genetic material into target cells. They are derived from naturally occurring viruses that have been modified to remove their disease-causing ability while retaining their ability to efficiently enter cells and deliver the desired genetic material. Viral vectors are designed to carry and introduce therapeutic genes, such as missing or mutated genes, into the cells of patients.
They act as delivery vehicles, transporting the genetic material to the target cells where it may be expressed and produce the desired therapeutic effect. Several types of viruses are commonly used as viral vectors, including adenoviruses, adeno-associated viruses (AAV), lentiviruses, retroviruses, and others. Each type of viral vector has unique characteristics and is selected on the basis of factors such as the target cell type, the desired duration of gene expression and others.
The viral vector production process involves modifying the viral genome to remove disease-causing elements and inserting the therapeutic gene of interest. The modified viral vector is then produced in enormous quantities through cell culture or other manufacturing methods. Quality control measures are implemented to ensure the safety, potency, and purity of the viral vector product.
The increase in prevalence of genetic disorders worldwide is a significant driving force behind the growth of the viral vector production market. Genetic conditions such as muscular dystrophy, cystic fibrosis, and hemophilia impact a large number of individuals globally. For instance, National Hemophilia Foundation (2023) there are between 30,000 to 33,000 people who live with hemophilia in the U.S. Gene therapy offers promising potential for treatment of these disorders, providing the possibility of a cure or long-term treatment options.
Moreover, viral vectors play a crucial role in gene therapy as they act as carriers, delivering therapeutic genes into the targeted cells to correct the underlying genetic defects. The growth in awareness and knowledge about gene therapy among healthcare professionals and patients has contributed to the rise in demand for viral vector production.
In addition, the global incidence of cancer has been on the rise, with a substantial number of new cases being diagnosed annually. This alarming trend has spurred significant interest in innovative treatment modalities, and viral vectors have emerged as pivotal components in gene therapy strategies for combating cancer. These specialized vectors have the ability to transport therapeutic genes or induce modifications in target cells, thereby amplifying immune responses against cancerous cells.
In addition, viral vector platforms play a critical role in the advancement of oncolytic viral therapies, which utilize viruses to directly target and eradicate cancer cells. The increase in demand for effective cancer treatments serves as a driving force behind the growth in need for viral vectors and their production. Furthermore, the COVID-19 pandemic has led to a significant rise in viral vector production for vaccine development.
Viral vectors, such as adenoviruses, have been utilized as a platform for the development of COVID-19 vaccines. These vectors are engineered to carry the genetic material of the SARS-CoV-2 spike protein, stimulating an immune response in vaccinated individuals. The urgent need for effective vaccines to combat the global health crisis has accelerated the production of viral vectors and thus contributed significantly to the growth of the market.
However, the viral vector production market faces certain restraints that may impede its growth and development. One significant restraint is the excessive cost associated with viral vector production. The manufacturing process requires substantial upfront capital investment, specialized infrastructure, and skilled personnel. In addition, the use of expensive raw materials and quality control measures further escalates production costs. These high costs may limit accessibility and affordability of gene therapies and viral vector-based vaccines, hindering the wider adoption and market growth.
On the contrary, the viral vector production market presents significant opportunities for growth and innovation. The increase in adoption of gene therapies and viral vector-based vaccines, coupled with the expanding pipeline of promising candidates, fuels the demand for viral vectors. Advancements in vector engineering, manufacturing technologies, and process optimization create opportunities for more efficient and cost-effective production.
Furthermore, developing regions present significant opportunities for growth in the viral vector production market. Rise in healthcare expenditures, developing healthcare infrastructure, government initiatives and support for treatment of complex diseases is further anticipated to boost the demand for viral vector production in this region.
The global viral vector production market is segmented based on viral vector type, indication, application, end user, and region. On the basis of viral vector type, the market is categorized into adenoviral vectors, adeno-associated viral vectors, lentiviral vectors, retroviral, and other viral vectors. On the basis of indication, it is segregated into cancer, genetic disorders, infectious diseases, and other diseases. On the basis of application, it is bifurcated into gene therapy, and vaccinology.
On the basis of region, the market is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and Rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and Rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and Rest of LAMEA). Major players that operate in the market include Andelyn Biosciences, Charles River Laboratories, Danaher Corporation., FinVector Oy, Lonza, Novartis AG, Oxford Biomedica plc, Takara Holdings Inc., Thermo Fisher Scientific Inc. and Avid Bioservices, Inc.