PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1565707
PUBLISHER: AnalystView Market Insights | PRODUCT CODE: 1565707
In-vitro Transcription Templates Market size was valued at USD 251.43 Million in 2023, expanding at a CAGR of 21.09% from 2024 to 2032.
In-vitro transcription templates are DNA sequences used to synthesize RNA in a controlled laboratory setting outside of a living organism. These templates serve as the blueprints for RNA synthesis and are essential in experiments where researchers want to produce specific RNA molecules.
In-vitro Transcription Templates Market- Market Dynamics
Growing demand from RNA-based therapeutics & vaccines and increasing research in biotech is also expected to propel market demand
The development of RNA-based therapeutics, including small interfering RNA (siRNA) and antisense oligonucleotides (ASOs), has increased demand for high-quality RNA production. mRNA vaccines, like those developed for COVID-19 disease like Pfizer-BioNTech and Moderna, have significantly boosted interest in in-vitro transcription (IVT) templates. The ability to rapidly design and produce mRNA vaccines has made in-vitro transcription crucial in pharmaceutical development. The rise of gene-editing tools like CRISPR-Cas9 uses in-vitro transcription to generate guide RNA (gRNA), which is critical for genome editing applications.
As personalized medicine evolves, the ability to produce tailor-made RNA for individualized treatments like cancer immunotherapies drives the demand for efficient IVT template technology. The need for efficient production of RNA for biosensors, bioengineering applications, and novel biological circuits continues to support the demand for transcription templates. In addition, the pharmaceutical and biotechnology industries are investing heavily in R&D, which supports the demand for transcription templates. Scientists use in-vitro transcription templates to study gene expression, protein synthesis, and cellular mechanisms.
In-vitro Transcription Templates Market- Key Insights
As per the analysis shared by our research analyst, the global market is estimated to grow annually at a CAGR of around 21.09% over the forecast period (2024-2032)
Based on Product segmentation, the DNA templates segment was predicted to show maximum market share in the year 2023, owing to their higher efficiency in driving transcription.
Based on Application segmentation, vaccines segment was the leading Application segment in 2023, due to the growing prevalence of COVID-19 and other viral infections.
Based on Disease Type segmentation, cancer segment was the leading Disease Type segment in 2023, due to prevalence of lung cancer, leukemia, breast cancer, etc.
On the basis of region, North America was the leading revenue generator in 2023, due to the government support in research & new drugs development.
The Global In-vitro Transcription Templates Market is segmented on the basis of Product, Application, Disease Type, and Region.
The market is divided into four categories based on Product: DNA templates, RNA templates, templates & transcription kits, and others. The DNA templates segment dominates the market. DNA templates offer high efficiency & are robust in sequencing & transcription process which is contributing to market growth.
The market is divided into two categories based on Application: vaccines and therapeutics. The vaccines segment dominates the market. The vaccines are mainly used in targeting viral infections and are more effective than other type boosting market growth.
The market is divided into five categories based on Disease Type: cancer, infectious diseases, genetic diseases lifestyle diseases, and others. The cancer segment dominates the market and is expected to maintain its high dominance during the forecast period. The growing prevalence of lung, breast cancer, leukemia are supplementing segment growth.
In-vitro Transcription Templates Market- Geographical Insights
Geographically, this market is widespread in the regions of North America, Latin America, Europe, Asia Pacific, and the Middle East and Africa. North America held the largest revenue share in the global market. The U.S. dominates the global market due to its well-established biotechnology and pharmaceutical sectors, particularly in the development of RNA-based therapies and vaccines. In Asia Pacific, China is rapidly emerging as a key player in the IVT template market due to its growing biotech sector, increasing investments in RNA-based therapeutics, and government support for biotechnology R&D. Increased government focus on healthcare innovation and collaborations with global pharma companies are driving the market.
The In-vitro Transcription (IVT) Templates market is significantly competitive, with several key players across the biotechnology and pharmaceutical industries focusing on innovations in RNA-based technologies. These companies are investing in developing high-quality transcription templates for RNA production, enabling advancements in areas like mRNA vaccines, RNA-based therapeutics, and gene editing. Key players are forming alliances with pharmaceutical companies to supply critical IVT components for the production of RNA-based vaccines and therapeutics. Companies like TriLink, Aldevron, and Merck are heavily investing in expanding their manufacturing capabilities, particularly for high-quality RNA production, to meet the growing demand for mRNA vaccines and RNA-based drugs.
In September 2023, Merck became the first CTDMO to offer fully integrated services for mRNA development, manufacturing, commercialization, and product testing.
In 2023, UK research councils such as the Medical Research Council (MRC) and the Biotechnology and Biological Sciences Research Council (BBSRC) allocated substantial funding for basic and applied research in RNA biology, genomics.