Oligonucleotide Synthesis Market,By Equipment and Services, By Technology, By Nucleic Acid, By Application, By End User, By Geography

Description

Oligonucleotide Synthesis Market is estimated to be valued at USD 4.69 Bn in 2025 and is expected to reach USD 9.68 Bn by 2032, growing at a compound annual growth rate (CAGR) of 10.9% from 2025 to 2032.

Report Coverage		Report Details
Base Year:	2024	Market Size in 2025:	USD 4.69 Bn
Historical Data for:	2020 To 2024	Forecast Period:	2025 To 2032
Forecast Period 2025 to 2032 CAGR:	10.90%	2032 Value Projection:	USD 9.68 Bn

Oligonucleotides are commonly used as primers for polymerase chain reaction (PCR), PCR assays, and panels for biologically related genes. Antisense oligonucleotides are used to reduce levels of protein synthesis by inhibiting mRNA processing or translation. Other uses of oligonucleotides include DNA sequencing, DNA microarrays, fluorescence in situ hybridization (FISH), and nucleic acid aptamers. Moreover, many pharmaceutical companies are focusing on developing nucleic acid-based therapeutics due to which the demand of oligonucleotide is increasing. Hence, market players are focusing on expanding their manufacturing facilities, which is expected to boost the market growth over the forecast period. For instance, in August 2020, Agilent Technologies Inc., announced the expansion of its state-of-the-art production facility in Frederick, Colorado, which develops manufactures oligos that hold potential to be used as treatments for diseases such as COVID-19, cardiovascular disease, cancer, rare and infectious diseases, and other conditions.

Market Dynamics:

Key players are focusing on various inorganic growth strategies such as collaborations, partnerships and agreements, which is expected to propel the growth of the global oligonucleotide synthesis market during the forecast period. For instance, on August 05, 2020, Evotec SE, a drug discovery and development company entered into a strategic partnership with Secarna Pharmaceuticals GmbH & Co. KG, a drug discovery company, for the development of antisense oligonucleotide therapies.

Moreover, in November 2019, CSBio, a peptide and instrumentation manufacturing company entered into a collaboration with Sunresin, a supplier of ion exchange resin and absorption & separation resin for the development of an optimized polystyrene resin for commercial scale oligonucleotide synthesis.

Key features of the study:

This report provides in-depth analysis of the global oligonucleotide synthesis market, and provides market size (US$ Bn) and compound annual growth rate (CAGR%) for the forecast period 2025-2032, considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global oligonucleotide synthesis market based on the following parameters - company overview, financial performance, product portfolio, market presence, distribution strategies, key developments, strategies, and future plans.
Key companies covered as a part of this study include Thermo Fisher Scientific, Sigma-Aldrich Corporation, GE Healthcare, Integrated DNA Technologies, Inc., TriLink BioTechnologies, Inc, BioAutomation Corporation, Twist Bioscience, Shanghai SynTheAll Pharmaceutical Co., CUSABIO Technology LLC, Synbio Technologies, GENEWIZ, Eurofins Scientific, Agilent Technologies, Kaneka Eurogentec S.A., and LGC, Biosearch Technologies
Insights from this report would allow marketers and management authorities of companies to make informed decisions regarding future product launches, market expansion, and marketing tactics
The global oligonucleotide synthesis market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global oligonucleotide synthesis market.

Detailed Segmentation:

Global Oligonucleotide Synthesis Market, By Equipment & Services:
- Equipment/Synthesizer
- Reagents
- Services
- Oligo Synthesis
- Modification
- Purification
Global Oligonucleotide Synthesis Market, By Technology:
- Column-based
- Microarray-based
Global Oligonucleotide Synthesis Market, By Nucleic Acid Type:
- DNA
- RNA
Global Oligonucleotide Synthesis Market, By Application:
- Drug Discovery
- Therapeutics
Global Oligonucleotide Synthesis Market, By End User:
- Academic Research Institutes
- Diagnostic Laboratories
- Pharmaceutical-Biotechnology Companies
Global Oligonucleotide Synthesis Market, By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
Company Profiles
- Thermo Fisher Scientific
- Sigma-Aldrich Corporation
- GE Healthcare
- Integrated DNA Technologies, Inc.
- TriLink BioTechnologies, Inc
- BioAutomation Corporation
- Twist Bioscience
- Shanghai SynTheAll Pharmaceutical Co.
- CUSABIO Technology LLC
- Synbio Technologies
- GENEWIZ
- Eurofins Scientific
- Agilent Technologies
- Kaneka Eurogentec S.A.
- LGC, Biosearch Technologies

Product Code: CMI4257

1. Research Objective and Assumption

Research Objectives
Assumptions
Abbreviations

2. Market Purview

Report Description
- Market Definition and Scope
Executive Summary
- Market Snippet, By Equipment and Services
- Market Snippet, By Technology
- Market Snippet, By Nucleic Acid
- Market Snippet, By Application
- Market Snippet, By End User
- Market Snippet, By Region
- Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

Market Dynamics
- Drivers
- Restraints
- Market Opportunities
Impact Analysis
Recent Test Launches
Epidemiology
Merger, Acquisition, and Collaborations
Regulatory Scenario
Key Developments
PEST Analysis

4. Global Oligonucleotide Synthesis Market - COVID-19 Impact Analysis

Economic Impact
COVID-19 Epidemiology
Impact on Supply and Demand

5. Global Oligonucleotide Synthesis Market, By Equipment and Services, 2020- 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
Equipment and Services
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Nucleic Acid Synthesizer
Peptide Synthesizer
Reagents
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Services
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Oligo Synthesis
Modification
Purification

6. Global Oligonucleotide Synthesis Market, By Technology, 2020 - 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
ColuBn-based
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Microarray-based
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends

7. Global Oligonucleotide Synthesis Market, By Nucleic Acid, 2020 - 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
DNA
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
RNA
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends

8. Global Oligonucleotide Synthesis Market, By Application, 2020 - 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
Drug Discovery
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Therapeutics
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends

9. Global Oligonucleotide Synthesis Market, By End User, 2020 - 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
Academic Research Institutes
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Diagnostic Laboratories
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends
Pharmaceutical-biotechnology Companies
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
- Segment Trends

10. Global Oligonucleotide Synthesis Market, By Region, 2020 - 2032, (US$ Bn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021-2032
- Segment Trends
North America
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 -2032, (US$ Bn)
  - U.S.
  - Canada
Europe
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 -2032, (US$ Bn)
  - U.K.
  - Germany
  - Italy
  - France
  - Spain
  - Russia
  - Rest of Europe
Asia Pacific
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 -2032, (US$ Bn)
  - China
  - India
  - Japan
  - ASEAN
  - Australia
  - South Korea
  - Rest of Asia Pacific
Latin America
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 -2032, (US$ Bn)
  - Brazil
  - Mexico
  - Argentina
  - Rest of Latin America
Middle East
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 -2032, (US$ Bn)
  - GCC
  - Israel
  - Rest of Middle East
Africa
- Introduction
- Market Size and Forecast, Y-o-Y Growth and By Equipment and Services, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Technology, 2020 -2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Nucleic Acid, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By Application, 2020-2032, (US$ Bn)
- Market Size and Forecast, Y-o-Y Growth and By End User, 2020-2032, (US$ Bn)
- Market Size and Forecast, By Country, Y-o-Y Growth and By Country/Region, 2020 -2032, (US$ Bn)
  - North Africa
  - Central Africa
  - South Africa

11. Competitive Landscape

Company Profiles
- Thermo Fisher Scientific Inc.*
  - Company Overview
  - Product Portfolio
  - Key Highlights
  - Financial Overview
  - Strategies
- Merck KGaA
- Danaher Corporation
- Twist Bioscience
- STA Pharmaceutical Co. Ltd.
- KINOVATE LIFE SCIENCES
- CUSABIO TECHNOLOGY LLC
- Synbio Technologies
- GENEWIZ
- Agilent Technologies, Inc.
- Maravai LifeSciences Holdings, Inc.
- Biogen
- Eurofins Scientific
- Sarepta Therapeutics, Inc.
- LGC Limited
- Kaneka Corporation
- Biotage
- Nitto Denko Corporation

12. Section

References
Research Methodology
About us and Sales Contact