Pertussis - Epidemiology Forecast - 2036

Pertussis Insights and Trends

• Pertussis, literally meaning "a violent cough," and also known as whooping cough, is an acute respiratory infection caused by Bordetella pertussis. There are three different stages of pertussis: catarrhal, paroxysmal and convalescent.
• Pertussis (whooping cough) is common in the United States, with increases in the number of cases usually occurring every few years.
• Pertussis can cause serious illness in babies, children, teens, and adults. Symptoms of pertussis usually develop within 5-10 days after exposure. Sometimes pertussis symptoms do not develop for as long as 3 weeks. The severity of the symptoms depends on several factors, including the patient's age, the strength of the immune response, and the extent of systemic bacterial dissemination.
• The rising incidence of pertussis, due to inadequate immunization and waning immunity among vaccinated groups, is driving market demand for vaccines and treatments. This resurgence highlights the need for enhanced vaccination programs to curb transmission rates. Increased awareness and healthcare investments are further accelerating this demand.
• Country-specific Vaccination Coverage of Pertussis was ~34 million in the leading markets (the United States, the EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan) in 2025.

Pertussis Epidemiology Forecast in the United States

• Country-specific Vaccination Coverage of Pertussis:Approximately~34 million
• Pertussis Growth Rate (2026-2036): 0.5% CAGR

DelveInsight's 'Pertussis- Epidemiology Forecast - 2036' report delivers an in-depth understanding of the Pertussis, historical and forecasted epidemiology in the United States, EU4 (Germany, Spain, Italy, and France) and the United Kingdom, and Japan.

Pertussis Understanding and Diagnosis Algorithm

Pertussis Overview

Pertussis, also known as whooping cough or the "cough of 100 days," is a highly contagious respiratory infection caused by Bordetella pertussis. It is characterized by a prolonged paroxysmal cough with a distinctive "whoop," vomiting, and possible syncope, and spreads through respiratory droplets. Although traditionally a childhood disease, over half of cases now occur in adolescents and adults due to waning immunity. The disease progresses through catarrhal, paroxysmal, and convalescent stages, and despite vaccination, it remains a public health concern. Diagnosis is based on clinical features and confirmed by PCR, culture, or serology, with early detection critical to control transmission and initiate treatment.

Pertussis Diagnosis

Diagnosis of pertussis is based on a combination of clinical presentation and laboratory confirmation, with suspicion arising in patients presenting with persistent and paroxysmal cough, particularly in high-risk groups such as infants. Confirmation is primarily achieved through PCR in the early stages, while culture and serology are used depending on disease progression. The infection spreads via aerosols and affects the ciliated epithelium of the respiratory tract, where bacterial toxins contribute to disease manifestations. Despite advances in understanding, gaps remain in disease pathogenesis, especially in severe infant cases, and ongoing research aims to support the development of improved vaccines and treatment strategies.

Pertussis Epidemiology

Key Findings from Pertussis Epidemiological Analysis and Forecast

• In 2025, the US accounted for the highest cases of pertussis i.e., 60% of the total cases in the 7MM.
• Among the 7MM, vaccination coverage for children is reported to be high; in comparison, booster vaccination compliance among adults is reported to be low owing to the fact. With the increasing awareness, the updation of immunization recommendations and the entry of emerging vaccines are expected to increase the vaccination coverage rate.
• As per DelveInsight's estimate, the total Pertussis vaccinated population in the US was approximately 20 million in 2025 and is projected to increase during the forecast period (2026-2036).
• Pertussis infection can lead to complications, particularly pneumonia (lung infection) in infants and older adults. In severe cases, infants may show signs such as poor feeding, irritability and unusual tiredness, while breathing difficulties can progress to respiratory distress.
• During periods of increased Whooping Cough transmission, health departments lead response efforts, with active screening in community settings aimed at reducing exposure, enabling timely diagnosis and treatment, and promoting appropriate use of preventive antibiotics.

Scope of the Report:

The report covers a segment of an executive summary, a descriptive overview of Pertussis, explaining its causes, signs and symptoms, and pathogenesis.

• Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of the diagnosis rate, and disease progression.

Report Insights

Pertussis Patient Population Forecast

Report Key Strengths

• Epidemiology-based (epi-based) Bottom-up Forecasting
• 11-year Forecast
• Patient Burden Trends (by geography)

FAQs:

• What are the disease risks, burdens, and unmet needs of Pertussis? What will be the growth opportunities across the 7MM concerning the patient population with Pertussis?
• What is the historical and forecasted Pertussis patient pool in the US, EU4 (Germany, France, Italy, and Spain), the UK, and Japan?

Reasons to Buy:

• Insights on patient burden/disease prevalence, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
• To understand key opinion leaders' perspectives around the diagnostic challenges to overcome barriers in the future.
• Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.