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PUBLISHER: Grand View Research | PRODUCT CODE: 1790481

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PUBLISHER: Grand View Research | PRODUCT CODE: 1790481

U.S. Antibiotic Resistance Market Size, Share, & Trends Analysis Report By Disease (cUTI, CDI), By Pathogen, By Drug Class, By Mechanism of Action, By Distribution Channel, And Segment Forecasts, 2025 - 2030

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U.S. Antibiotic Resistance Market Summary

The U.S. antibiotic esistance market size was estimated at USD 3.09 billion in 2024 and is projected to reach USD 3.99 billion by 2030, growing at a CAGR of 4.4% from 2025 to 2030. The market is expected to grow, driven by the rising misuse and overuse of antibiotics.

According to the CDC, more than 2.8 million antimicrobial-resistant infections are reported every year in the U.S., leading to 35,000 deaths. Moreover, the rise of public health concerns and the need for new antibiotic therapies are expected to drive market growth. According to the WHO, the overuse and misuse of antibiotics in animals, humans, and plants are the main reasons for the development of drug-resistant pathogens. Antibiotic resistance makes infections hard to treat and makes medical treatments, including cancer chemotherapy and surgeries such as cesarean sections and hip replacements, riskier. The market for antibiotic therapies is witnessing strong growth, driven by the urgent demand for treatments that can counteract rising resistance to existing drugs.

When a person contracts an infection caused by antibiotic-resistant bacteria, managing the illness becomes more challenging because fewer antibiotics can effectively treat the infection. In addition, these resistant bacteria can be transmitted to others, increasing the risk of wider spread. There are some rare instances where very few treatment options may be available.

U.S. Antibiotic Resistance Market Report Segmentation

This report forecasts revenue at the country level and analyzes the latest industry trends in each sub-segment from 2018 to 2030. For this study, Grand View Research has segmented the U.S. Antibiotic Resistance Market report based on disease, pathogen, drug class, mechanism of action, and distribution channel:

  • Disease Outlook (Revenue in USD Million, 2018 - 2030)
  • cUTI
  • CDI
  • ABSSSI
  • HABP
  • CABP
  • cIAI
  • BSI
  • Pathogen Outlook (Revenue in USD Million, 2018 - 2030)
  • E. coli
  • klebsiella pneumoniae
  • P. aeruginosa
  • S. aureus
  • baumannii
  • Strep. Pneumoniae
  • H. influenzae
  • CDI
  • Enterococcus fecium
  • Drug Class Outlook (Revenue in USD Million; 2018 - 2030)
  • Oxazolidinones
  • Lipoglycopeptides
  • Tetracyclines
  • Combination therapies
  • Cephalosporins
  • Others
  • Mechanism of Action Outlook (Revenue in USD Million; 2018 - 2030)
  • Protein Synthesis Inhibitors
  • Cell Wall Synthesis Inhibitors
  • RNA Synthesis Inhibitors
  • DNA Synthesis Inhibitors
  • Others
  • Distribution Channel Outlook (Revenue in USD Million; 2018 - 2030)
  • Retail Pharmacies
  • Hospital Pharmacies
  • Online Pharmacies
Product Code: GVR-4-68040-664-4

Table of Contents

Chapter 1. Methodology and Scope

  • 1.1. Market Segmentation & Scope
  • 1.2. Segment Definitions
    • 1.2.1. Disease
    • 1.2.2. Pathogen
    • 1.2.3. Drug Class
    • 1.2.4. Mechanism of Action
    • 1.2.5. Distribution Channel
    • 1.2.6. Estimates and forecasts timeline
  • 1.3. Research Methodology
  • 1.4. Information Procurement
    • 1.4.1. Purchased database
    • 1.4.2. GVR's internal database
    • 1.4.3. Secondary sources
    • 1.4.4. Primary research
    • 1.4.5. Details of primary research
  • 1.5. Information or Data Analysis
    • 1.5.1. Data analysis models
  • 1.6. Market Formulation & Validation
  • 1.7. Model Details
  • 1.8. List of Secondary Sources
  • 1.9. List of Primary Sources
  • 1.10. Objectives

Chapter 2. Executive Summary

  • 2.1. Market Outlook
  • 2.2. Segment Outlook
    • 2.2.1. Disease outlook
    • 2.2.2. Pathogen outlook
    • 2.2.3. Drug Class outlook
    • 2.2.4. Mechanism of Action
    • 2.2.5. Distribution Channel
  • 2.3. Competitive Insights

Chapter 3. U.S. Antibiotic Resistance Market Variables, Trends & Scope

  • 3.1. Market Lineage Outlook
    • 3.1.1. Parent market outlook
    • 3.1.2. Related/ancillary market outlook
  • 3.2. Market Dynamics
    • 3.2.1. Market driver analysis
    • 3.2.2. Market restraint analysis

Chapter 4. U.S. Antibiotic Resistance Market Analysis Tools

  • 4.1. Industry Analysis - Porter's
    • 4.1.1. Supplier power
    • 4.1.2. Buyer power
    • 4.1.3. Substitution threat
    • 4.1.4. Threat of new entrant
    • 4.1.5. Competitive rivalry
  • 4.2. PESTEL Analysis
    • 4.2.1. Political landscape
    • 4.2.2. Technological landscape
    • 4.2.3. Economic landscape
  • 4.3. U.S. Antibiotic Resistance Market: Pipeline Analysis

Chapter 5. U.S. Antibiotic Resistance Market: Disease Estimates & Trend Analysis

  • 5.1. Disease Segment Dashboard
  • 5.2. U.S. Antibiotic Resistance Market: Disease Movement Analysis
  • 5.3. U.S. Antibiotic Resistance Market Size & Trend Analysis, by Disease, 2018 to 2030 (USD Million)
  • 5.4. cUTI
    • 5.4.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.5. CDI
    • 5.5.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.6. ABSSSI
    • 5.6.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.7. HABP
    • 5.7.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.8. CABP
    • 5.8.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.9. cIAI
    • 5.9.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 5.10. BSI
    • 5.10.1. Market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 6. U.S. Antibiotic Resistance Market: Pathogen Estimates & Trend Analysis

  • 6.1. Pathogen Segment Dashboard
  • 6.2. U.S. Antibiotic Resistance Market: Pathogen Movement Analysis
  • 6.3. U.S. Antibiotic Resistance Market Size & Trend Analysis, by Pathogen, 2018 to 2030 (USD Million)
  • 6.4. E. coli
    • 6.4.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5. klebsiella pneumoniae
    • 6.5.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.6. P. aeruginosa
    • 6.6.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.7. S. aureus
    • 6.7.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.8. A. baumannii
    • 6.8.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.9. Strep. Pneumoniae
    • 6.9.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.10. H. influenzae
    • 6.10.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.11. CDI
    • 6.11.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.12. Enterococcus fecium
    • 6.12.1. Market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 7. U.S. Antibiotic Resistance Market: Drug Class Estimates & Trend Analysis

  • 7.1. Drug Class Segment Dashboard
  • 7.2. U.S. Antibiotic Resistance Market: Drug Class Movement Analysis
  • 7.3. U.S. Antibiotic Resistance Market Size & Trend Analysis, by Drug Class, 2018 to 2030 (USD Million)
  • 7.4. Oxazolidinones
    • 7.4.1. Market estimates and forecasts 2018 to 2030 (USD million)
  • 7.5. Lipoglycopeptides
    • 7.5.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 7.6. Tetracyclines
    • 7.6.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 7.7. Combination therapies
    • 7.7.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 7.8. Cephalosporins
    • 7.8.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 7.9. Others
    • 7.9.1. Market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 8. U.S. Antibiotic Resistance Market: Mechanism of Action Estimates & Trend Analysis

  • 8.1. Mechanism of Action Segment Dashboard
  • 8.2. U.S. Antibiotic Resistance Market: Mechanism of Action Movement Analysis
  • 8.3. U.S. Antibiotic Resistance Market Size & Trend Analysis, by Mechanism of Action, 2018 to 2030 (USD Million)
  • 8.4. Protein Synthesis Inhibitors
    • 8.4.1. Market estimates and forecasts 2018 to 2030 (USD million)
  • 8.5. Cell Wall Synthesis Inhibitors
    • 8.5.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 8.6. RNA Synthesis Inhibitors
    • 8.6.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 8.7. DNA Synthesis Inhibitors
    • 8.7.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 8.8. Others
    • 8.8.1. Market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 9. U.S. Antibiotic Resistance Market: Distribution Channel Estimates & Trend Analysis

  • 9.1. Distribution Channel Segment Dashboard
  • 9.2. U.S. Antibiotic Resistance Market: Distribution Movement Analysis
  • 9.3. U.S. Antibiotic Resistance Market Size & Trend Analysis, by Distribution Channel, 2018 to 2030 (USD Million)
  • 9.4. Retail Pharmacies
    • 9.4.1. Market estimates and forecasts 2018 to 2030 (USD million)
  • 9.5. Hospital Pharmacies
    • 9.5.1. Market estimates and forecasts 2018 to 2030 (USD Million)
  • 9.6. Online Pharmacies
    • 9.6.1. Market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 10. Competitive Landscape

  • 10.1. Recent Developments & Impact Analysis, By Key Market Participants
  • 10.2. Company/Competition Categorization
  • 10.3. Vendor Landscape
    • 10.3.1. Key company heat map analysis, 2024
  • 10.4. Company Profiles
    • 10.4.1. Melinta Therapeutics
      • 10.4.1.1. Company overview
      • 10.4.1.2. Financial performance
      • 10.4.1.3. Product benchmarking
      • 10.4.1.4. Strategic initiatives
    • 10.4.2. Merck & Co., Inc.
      • 10.4.2.1. Company overview
      • 10.4.2.2. Financial performance
      • 10.4.2.3. Product benchmarking
      • 10.4.2.4. Strategic initiatives
    • 10.4.3. Melinta Therapeutics LLC
      • 10.4.3.1. Company overview
      • 10.4.3.2. Financial performance
      • 10.4.3.3. Product benchmarking
      • 10.4.3.4. Strategic initiatives
    • 10.4.4. Theravance Biopharma.
      • 10.4.4.1. Company overview
      • 10.4.4.2. Financial performance
      • 10.4.4.3. Product benchmarking
      • 10.4.4.4. Strategic initiatives
    • 10.4.5. Paratek Pharmaceuticals, Inc.
      • 10.4.5.1. Company overview
      • 10.4.5.2. Financial performance
      • 10.4.5.3. Product benchmarking
      • 10.4.5.4. Strategic initiatives
    • 10.4.6. Seres Therapeutics
      • 10.4.6.1. Company overview
      • 10.4.6.2. Financial performance
      • 10.4.6.3. Product benchmarking
      • 10.4.6.4. Strategic initiatives
    • 10.4.7. AbbVie Inc.
      • 10.4.7.1. Company overview
      • 10.4.7.2. Financial performance
      • 10.4.7.3. Product benchmarking
      • 10.4.7.4. Strategic initiatives
Product Code: GVR-4-68040-664-4

List of Tables

  • Table 1 List of Abbreviations
  • Table 2 U.S. Antibiotic Resistance market, by Disease, 2018 - 2030 (USD Million)
  • Table 3 U.S. Antibiotic Resistance market, by Pathogen, 2018 - 2030 (USD Million)
  • Table 4 U.S. Antibiotic Resistance market, by Drug Class, 2018 - 2030 (USD Million)
  • Table 5 U.S. Antibiotic Resistance market, by Mechanism of Action, 2018 - 2030 (USD Million)
  • Table 6 U.S. Antibiotic Resistance market, by Distribution Channel, 2018 - 2030 (USD Million)

List of Figures

  • Fig. 1 Market research process
  • Fig. 2 Data triangulation techniques
  • Fig. 3 Primary research pattern
  • Fig. 4 Primary interviews
  • Fig. 5 Market research approaches
  • Fig. 6 Value-chain-based sizing & forecasting
  • Fig. 7 QFD modeling for market share assessment
  • Fig. 8 Market formulation & validation
  • Fig. 9 U.S. antibiotic resistance market: market outlook
  • Fig. 10 U.S. antibiotic resistance competitive insights
  • Fig. 11 Parent market outlook
  • Fig. 12 Related/ancillary market outlook
  • Fig. 13 Penetration and growth prospect mapping
  • Fig. 14 Industry value chain analysis
  • Fig. 15 U.S. antibiotic resistance market driver impact
  • Fig. 16 U.S. antibiotic resistance market restraint impact
  • Fig. 17 U.S. antibiotic resistance market strategic initiatives analysis
  • Fig. 18 U.S. antibiotic resistance market: Disease movement analysis
  • Fig. 19 U.S. antibiotic resistance market: Disease outlook and key takeaways
  • Fig. 20 cUTI market estimates and forecast, 2018 - 2030
  • Fig. 21 CDI estimates and forecast, 2018 - 2030
  • Fig. 22 ABSSSI market estimates and forecast, 2018 - 2030
  • Fig. 23 HABP market estimates and forecast, 2018 - 2030
  • Fig. 24 CABP market estimates and forecast, 2018 - 2030
  • Fig. 25 cIAI estimates and forecast, 2018 - 2030
  • Fig. 26 BSI estimates and forecast, 2018 - 2030
  • Fig. 27 U.S. antibiotic resistance market: Pathogen movement analysis
  • Fig. 28 U.S. antibiotic resistance market: Pathogen outlook and key takeaways
  • Fig. 29 E. coli market estimates and forecasts, 2018 - 2030
  • Fig. 30 klebsiella pneumoniae market estimates and forecasts, 2018 - 2030
  • Fig. 31 P. aeruginosa market estimates and forecasts, 2018 - 2030
  • Fig. 32 S. aureus market estimates and forecasts, 2018 - 2030
  • Fig. 33 A. baumannii market estimates and forecasts, 2018 - 2030
  • Fig. 34 Strep. Pneumoniae market estimates and forecasts, 2018 - 2030
  • Fig. 35 H. influenzae market estimates and forecasts, 2018 - 2030
  • Fig. 36 CDI market estimates and forecasts, 2018 - 2030
  • Fig. 37 Enterococcus fecium market estimates and forecasts, 2018 - 2030
  • Fig. 38 U.S. antibiotic resistance market: Drug class movement analysis
  • Fig. 39 U.S. antibiotic resistance market: Drug class outlook and key takeaways
  • Fig. 40 Oxazolidinones market estimates and forecasts, 2018 - 2030
  • Fig. 41 Lipoglycopeptides market estimates and forecasts, 2018 - 2030
  • Fig. 42 Tetracyclines market estimates and forecasts, 2018 - 2030
  • Fig. 43 Combination therapies market estimates and forecasts, 2018 - 2030
  • Fig. 44 Cephalosporins market estimates and forecasts, 2018 - 2030
  • Fig. 45 Others market estimates and forecasts, 2018 - 2030
  • Fig. 46 U.S. antibiotic resistance market: Mechanism of action movement analysis
  • Fig. 47 U.S. antibiotic resistance market: Mechanism of action outlook and key takeaways
  • Fig. 48 Protein synthesis inhibitors market estimates and forecasts, 2018 - 2030
  • Fig. 49 Cell wall synthesis inhibitors market estimates and forecasts, 2018 - 2030
  • Fig. 50 RNA synthesis inhibitors market estimates and forecasts, 2018 - 2030
  • Fig. 51 DNA synthesis inhibitors market estimates and forecasts, 2018 - 2030
  • Fig. 52 Others market estimates and forecasts, 2018 - 2030
  • Fig. 53 U.S. antibiotic resistance market: Distribution channel movement analysis
  • Fig. 54 U.S. antibiotic resistance market: Distribution channel outlook and key takeaways
  • Fig. 55 Retail pharmacies market estimates and forecasts, 2018 - 2030
  • Fig. 56 Hospital pharmacies market estimates and forecasts, 2018 - 2030
  • Fig. 57 Online pharmacies market estimates and forecasts, 2018 - 2030
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