PUBLISHER: Grand View Research | PRODUCT CODE: 1842260
PUBLISHER: Grand View Research | PRODUCT CODE: 1842260
The global foot and ankle orthobiologics market size was estimated at USD 746.44 million in 2024 and is projected to reach USD 1.47 billion by 2033, growing at a CAGR of 7.87% from 2025 to 2033. The growing burden of osteoporosis and degenerative disorders is one of the key factors driving the growth of the market.
According to the Oxford University Press article published in June 2025, from around 256 million people in 1990 to over 600 million in 2021 had osteoarthritis, with projections nearing 765 million by 2060 has created significant pressure on healthcare systems to deliver more effective musculoskeletal treatments. As foot and ankle joints are often among the first to experience degenerative changes, the demand for biologic interventions such as demineralized bone matrix, allografts, bone morphogenetic proteins, and stem cell therapies is rising, as these options support joint preservation and bone healing.
Moreover, as per the Elsevier B.V. article published in September 2024, ankle osteoarthritis, though less common than knee or hip disease, affects nearly 1% of adults worldwide and represents about 3% of all osteoarthritis cases, with an incidence of roughly 30 per 100,000 people. Its impact on mobility and quality of life is substantial, often leading to pain, stiffness, and functional decline that require medical intervention. For many of these patients, biologic options such as demineralized bone matrix, allografts, bone morphogenetic proteins, and stem cell therapies are being utilized to promote bone healing and joint preservation. At the same time, wedges including viscosupplementation and synthetic bone substitutes are increasingly applied to reduce joint stress and delay more invasive procedures. Hospitals typically manage advanced cases through reconstructive surgeries, while outpatient clinics are adopting injectable and minimally invasive biologic therapies for earlier stages. This rising clinical burden of ankle osteoarthritis is therefore directly fueling the adoption of both biologic and wedge-based orthobiologic solutions across care settings.
Global Foot And Ankle Orthobiologics Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and analyzes industry trends in each sub-segments from 2021 to 2033. For this study, Grand View Research, Inc. has segmented the global foot and ankle orthobiologics market report based on product, end use, and region: