PUBLISHER: Grand View Research | PRODUCT CODE: 2040701
PUBLISHER: Grand View Research | PRODUCT CODE: 2040701
The global osteoarthritis injectable market size was valued at USD 8.18 billion in 2025 and is projected to reach USD 14.16 billion by 2033, growing at a CAGR of 7.17% from 2026 to 2033. This growth is primarily driven by the increasing prevalence of osteoarthritis (OA), particularly among the aging population, as well as rising awareness of minimally invasive treatment options.
Additionally, advancements in biologic therapies and next-generation injectable, along with supportive reimbursement policies in key regions, are expected to further propel market expansion over the forecast period. R&D activities in injectable osteoarthritis therapies are accelerating due to challenges in delivering drugs into dense joint tissues. Companies are focusing on intra-articular biologics and disease-modifying agents. Candidates like lorecivivint from Biosplice Therapeutics and TPX-100 from OrthoTrophix highlight ongoing innovation. For instance, in January 2026, Biosplice Therapeutics submitted a New Drug Application (NDA) to the U.S. FDA for lorecivivint, an intra-articular injection for knee osteoarthritis, which showed promising Phase III results for pain reduction and functional improvement.
Similarly, in March 2026, OrthoTrophix advanced its Phase 2b clinical trial of TPX-100 by completing patient enrollment, reinforcing its position in developing disease-modifying intra-articular therapies targeting cartilage regeneration in osteoarthritis. The growing emphasis on personalized medicine is reshaping the OA injectable market, with a greater focus on patient-specific biologics and regenerative therapies. Research from Columbia University on cartilage-regenerating stem cells highlights the potential for precision-based injectable treatments targeting early-stage disease progression.
Global Osteoarthritis Injectable Market Repoprt Segmentation
This report forecasts revenue growth at, regional & country levels and provides an analysis on the industry trends in each of the sub-segments from 2021 to 2033. For the purpose of this study, Grand View Research has segmented the global osteoarthritis injectable market report on the basis of injection type, anatomy, end use, and region: