PUBLISHER: Grand View Research | PRODUCT CODE: 2067509
PUBLISHER: Grand View Research | PRODUCT CODE: 2067509
The global cancer biomarkers market size was valued at USD 26.92 billion in 2025 and is projected to reach USD 65.30 billion by 2033, growing at a CAGR of 11.82% from 2026 to 2033. The growth is attributed to rising cancer cases and the increasing focus on early diagnosis and personalized treatment.
Advancements in genomics, proteomics, next-generation sequencing, and molecular diagnostic technologies are accelerating innovation in the cancer biomarker testing market. Hospitals and labs are adopting biomarker-based tests to improve outcomes. Supportive government initiatives and expanding research activities further boost growth, while demand for targeted therapies continues to create new opportunities worldwide.
Cancer remains one of the leading global health challenges and a major cause of mortality in the 21st century. According to a study published in The Lancet in September 2025, findings from the Global Burden of Disease (GBD) 2023 study indicate that cancer burden was assessed across 47 cancer types in 204 countries and territories from 1990 to 2023, with projections extending to 2050. Cancer was estimated to be the second leading cause of death globally in 2023, after cardiovascular diseases, with total cancer-related deaths expected to exceed 18 million by 2050. Furthermore, estimates published by the Institute for Health Metrics and Evaluation in September 2025 indicate that there were 18.5 million new cancer cases and more than 10.4 million deaths globally, contributing to approximately 271 million disability-adjusted life years (DALYs) lost. Of these, nearly 60% of cancer cases and over 60% of cancer deaths occurred in low- and middle-income countries, highlighting significant disparities in disease burden and access to care. Lung cancer and colorectal cancer were identified as the leading and second-leading causes of cancer-related deaths in 2023, respectively. The increasing number of patients requiring ongoing care is expected to accelerate the adoption of biomarker-based technologies, thereby supporting the growth of the cancer biomarkers market.
Research plays a critical role in advancing the cancer biomarkers market by supporting the development of innovative technologies for early diagnosis, targeted therapy selection, and disease monitoring. Increasing government funding continues to accelerate oncology research and biomarker discovery initiatives. The National Cancer Institute (NCI) remains a major contributor, supporting research activities across its headquarters in Maryland, academic institutions, and global collaborations. According to data published by the NCI in July 2025, the institute's funds totaled USD 7.2 billion, with 43.3% of the obligated budget allocated to Research Project Grants. These investments are significantly advancing biomarker-based diagnostics, precision oncology, immuno-oncology, and liquid biopsy technologies, thereby supporting innovation and growth in the cancer biomarkers market.
Technological advancements are transforming the cancer biomarkers market by improving precision oncology, early detection, and personalized treatment selection. Increasing integration of biomarker-driven diagnostics with targeted therapies continues to expand clinical applications. For instance, in January 2025, Roche received FDA approval for its PATHWAY HER2 (4B5) companion diagnostic test for identifying patients with HER2-ultralow metastatic breast cancer, highlighting advancements in biomarker-based patient stratification. Continuous innovation in liquid biopsy technologies is also accelerating market growth. In June 2024, Guardant Health expanded the clinical application of its Guardant360 liquid biopsy test for comprehensive genomic profiling and real-time tumor monitoring. Furthermore, in August 2024, Illumina advanced its oncology sequencing platforms, supporting high-throughput genomic profiling and strengthening biomarker-based precision oncology applications across multiple cancer types.
Global Cancer Biomarkers Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global cancer biomarkers market report based on type, biomolecule, application, technology, and region