Oligonucleotide Synthesis Markets. Forecasts by Oligo Length, Application, and Product. With Executive and Consultant Guides. 2023 to 2027

Synthetic Oligonucleotides are poised for explosive growth as gene technology moves into mainstream healthcare, food production and, even, Data Storage! We are not kidding. The market for small snippets of DNA, called Oligonucleotides, is growing into a market for Synthetic DNA where organisms, like algae, are "custom designed" to produce food and medicine while consuming few resources. In applications like CRSPR Gene Editing and COVID-19 Synthetic Antibodies these "Oligos" are already going to work. The possibilities, and market growth are unlimited. Our analysis shows that investors do not yet understand the scope of this technology and the enormous market opportunity. Small biotechs are in a position to become huge multinationals, all based on producing DNA and its building blocks. Learn all about it and see our forecasts in this comprehensive report.

This is a complex area but this readable report will bring the entire management team up to speed, on both the technology and the opportunity. The technology is moving fast. It is coming out of the lab and onto the desktop as genetics crosses the chasm into mainstream commerce.

ABOUT THE LEAD AUTHOR:

Mr. Greg Powell, B.SC., M.B.A is the President of Howe Sound Research. He is an experienced business and clinical professional. He is co-author of the paper "The Radioimmunoassay of Angiotensinogen by Antibody Trapping." He has worked in laboratory testing and management for over 20 years. Mr. Powell's education includes:

B.Sc. (Chemistry) University of BC
M.B.A. (Finance and Policy) University of BC
Market Research Seminar - Burke Institute
Finance for Senior Executives - Harvard Business School

1 Market Guides

1.1 Situation Analysis
1.2 Guide for Executives and Marketing Staff
1.3 Guide for Investment Analysts and Management Consultants

2 Introduction and Market Definition

2.1 What is Oligonucleotide Synthesis?
- 2.1.1 The Enzyme Race
- 2.1.2 Data Storage - The Elephant in the Room
2.2 Market Definition
- 2.2.1 Market Size
- 2.2.2 Currency
- 2.2.3 Years
2.3 Methodology
- 2.3.1 Methodology
- 2.3.2 Sources
- 2.3.3 Authors
2.4 Perspective: Healthcare and the IVD Industry
- 2.4.1 Global Healthcare Spending
- 2.4.2 Spending on Diagnostics
- 2.4.3 Important Role of Insurance for Diagnostics

3 Oligonucleotide Synthesis

3.1 Synthesis Technology
3.2 Automation
3.3 Types of Oligonucleotides
3.4 PCR Primers
3.5 PCR Assays and Panels
3.6 Sequencing
3.7 DNA Microarrays
3.8 Fluorescence In Situ Hybridization (FISH)
3.9 Antisense Oligonucleotides
3.10 Other Uses of Oligonucleotides
3.11 Relationship to CRISPR and Gene Editing

4 Industry Overview

4.1 Players in a Dynamic Market
- 4.1.1 Academic Research Lab
- 4.1.2 Diagnostic Test Developer
- 4.1.3 Instrumentation Supplier
- 4.1.4 Chemical/Reagent Supplier
- 4.1.5 Pathology Supplier
- 4.1.6 Independent Clinical Laboratory
- 4.1.7 Public National/regional Laboratory
- 4.1.8 Hospital Laboratory
- 4.1.9 Physicians Office Lab (POLS)
- 4.1.10 Audit Body
- 4.1.11 Certification Body

5 Market Factors

5.1 Factors Driving Growth
- 5.1.1 The Role of Diagnostics and the Covid Effect
- 5.1.2 The RNA Based Vaccine
- 5.1.3 Genomic Blizzard
- 5.1.4 Antisense Revival
- 5.1.5 New Applications
5.2 Factors Limiting Growth
- 5.2.1 Declining Price
- 5.2.2 Technology Lag
- 5.2.3 COVID Realignment
5.3 The Next Five Years

6 Oligonucleotide Synthesis Recent Developments

6.1 Recent Developments - Importance and How to Use This Section
- 6.1.1 Importance of These Developments
- 6.1.2 How to Use This Section
6.2 Oligonucleotide Synthesis Scaled Up
6.3 Antisense Oligonucleotide Lowers Tau Tangles
6.4 Ansa Biotechnologies Synthesizes Longest Oligo at 1005 Bases
6.5 Agilent will double oligonucleotide capacity
6.6 RNA Synthesis Technology Commercialized by EnPlusOne
6.7 Quick and Automated Printing of Custom Oligos
6.8 WuXi STA Opens Large-Scale Oligo Manufacturing Facility
6.9 Secarna Pharmaceuticals' and Evotec Achieve Programme Designation
6.10 Aligos Discontinues Development of its Antisense Oligonucleotide
6.11 Seegene Obtains CE Mark for Oligo Based SARS-CoV-2 Assay
6.12 Biofidelity to Launch Mutation Detection Assay
6.13 Oligonucleotide Therapeutics Society Holds Meeting
6.14 New Oligonucleotide Synthesis Chemistry
6.15 Antisense Oligonucleotides Cross Rodents' Blood-Brain Barrier
6.16 New Rapid Multiplexed PCR Assay Uses Oligo Probes
6.17 MIT Devises Oligo 'File System' for DNA Data Storage
6.18 Nuclera Acquires E Ink Digital Microfluidics Business
6.19 Twist Bioscience Hits Milestone for DNA Data Storage
6.20 Twist Bioscience, Vivlion Partner on RNA Libraries for CRISPR
6.21 DNA Script Launching Benchtop Synthesizer for 'DNA on Demand'
6.22 RNA Disease Dx to Develop PoC Covid Test
6.23 Evonetix and Analog Devices Develop GEN3 DNA Synthesis Platform
6.24 ATDBio Receives Grant for Cancer Diagnosis Project
6.25 Twist Bioscience Announces SARS-CoV-2 Therapeutic Ab
6.26 Drugmakers boost oligo capacity amid Covid-19
6.27 Aligos Therapeutics in Study of Oligo Candidate
6.28 DNA Script Raises $89M for SYNTAX Launch
6.29 Codexis & Molecular Assemblies Partner for DNA Synthesis
6.30 NuProbe Licenses Oligo Technology from Rice
6.31 Genome editing with Cas9-oligo conjugates
6.32 OliX Pharma and AM Chemicals Partner for RNA Synthesis Support
6.33 Twist Bio To End Trade Secrets Suit
6.34 DNA Script, partners get grant for data storage
6.35 Xi's STA unit opens oligonucleotide plant

7 Profiles of Key Companies

7.1 Abbott Laboratories
7.2 Ajinomoto Bio-Pharma
7.3 Alnylam Pharmaceuticals
7.4 Amyris
7.5 Ansa BioTechnologies
7.6 ATDBio
7.7 ATG:biosynthetics
7.8 ATUM
7.9 Bayer
7.10 Beckman Coulter Diagnostics
7.11 Becton, Dickinson and Company
7.12 Biomatik
7.13 bioMérieux Diagnostics
7.14 Bioneer Corporation
7.15 Bio-Rad Laboratories, Inc.
7.16 Bio-Synthesis
7.17 Blue Heron Biotechnology (Eurofins Genomic)
7.18 Camena Bioscience
7.19 Cepheid (Danaher)
7.20 Codexis
7.21 Diasorin S.p.A.
7.22 DNA Script
7.23 Enzo Biochem
7.24 Eurofins Scientific
7.25 Eurogentec (Kaneka)
7.26 Evonetix
7.27 GE Healthcare
7.28 Genomatica
7.29 Genscript Biotech
7.30 Hologic
7.31 Integrated DNA Technologies (Danaher)
7.32 Ionis Pharmaceuticals
7.33 Janssen Diagnostics
7.34 Kern Systems
7.35 LGC Biosearch Technologies
7.36 Maravai LifeSciences Holdings
7.37 Merck & Co., Inc
7.38 Microsynth
7.39 Millipore Sigma
7.40 Molecular Assemblies
7.41 New England Biolabs, Inc.
7.42 Nitto Denko (Avecia)
7.43 Nuclera
7.44 Primerdesign (Novacyt)
7.45 Qiagen
7.46 Revvity
7.47 Roche Molecular Diagnostics
7.48 Seegene
7.49 Siemens Healthineers
7.50 Synthego
7.51 Thermo Fisher Scientific Inc.
7.52 Twist Bioscience

8 Oligonucleotide Synthesis Global Market Overview

8.1 Global Market Overview by Country
- 8.1.1 Table - Global Market by Country
- 8.1.2 Chart - Global Market by Country
8.2 Global Market Size by Length - Overview
- 8.2.1 Table - Global Market by Length
- 8.2.2 Chart - Global Market by Length - Base/Final Year Comparison
- 8.2.3 Chart - Global Market by Length - Base Year
- 8.2.4 Chart - Global Market by Length - Final Year
- 8.2.5 Chart - Global Market by Length - Share by Year
- 8.2.6 Chart - Global Market by Length - Segment Growth
8.3 Global Market Size by Application - Overview
- 8.3.1 Table - Global Market by Application
- 8.3.2 Chart - Global Market by Application - Base/Final Year Comparison
- 8.3.3 Chart - Global Market by Application - Base Year
- 8.3.4 Chart - Global Market by Application - Final Year
- 8.3.5 Chart - Global Market by Application - Share by Year
- 8.3.6 Chart - Global Market by Application - Segment Growth
8.4 Global Market Size by Product - Overview
- 8.4.1 Table - Global Market by Product
- 8.4.2 Chart - Global Market by Product - Base/Final Year Comparison
- 8.4.3 Chart - Global Market by Product - Base Year
- 8.4.4 Chart - Global Market by Product - Final Year
- 8.4.5 Chart - Global Market by Product - Share by Year
- 8.4.6 Chart - Global Market by Product - Segment Growth

9 Global Market by Length

9.1 <20 mer Market
- 9.1.1 Table - <20 mer Market by Country
- 9.1.2 Chart - <20 mer Market Segment Growth
9.2 21-50 mer Market
- 9.2.1 Table - 21-50 mer Market by Country
- 9.2.2 Chart - 21-50 mer Market Segment Growth
9.3 51-100 mer Market
- 9.3.1 Table - 51-100 mer Market by Country
- 9.3.2 Chart - 51-100 mer Market Segment Growth
9.4 >100 mer Market
- 9.4.1 Table - >100 mer Market by Country
- 9.4.2 Chart - >100 mer Market Segment Growth

10 Global Market by Application

10.1 Research Market
- 10.1.1 Table - Research Market by Country
- 10.1.2 Chart - Research Market Segment Growth
10.2 Diagnostics Market
- 10.2.1 Table - Diagnostics Market by Country
- 10.2.2 Chart - Diagnostics Market Segment Growth
10.3 Therapeutics Market
- 10.3.1 Table - Therapeutics Market by Country
- 10.3.2 Chart - Therapeutics Market Segment Growth
10.4 Data Market
- 10.4.1 Table - Data Market by Country
- 10.4.2 Chart - Data Market Segment Growth

11 Global Market by Product

11.1 Oligonucleotides Market
- 11.1.1 Table - Oligonucleotides Market by Country
- 11.1.2 Chart - Oligonucleotides Market Segment Growth
11.2 Instruments Market
- 11.2.1 Table - Instruments Market by Country
- 11.2.2 Chart - Instruments Market Segment Growth
11.3 Reagents Market
- 11.3.1 Table - Reagents Market by Country
- 11.3.2 Chart - Reagents Market Segment Growth

12 Appendices

12.1 Typical Oligo Synthesis Price Lists
12.2 Medicare Clinical Lab Fee Schedule
12.3 Share of Pharma R&D by Country

Table of Tables

Table 1 Companies Formed to Exploit Enzyme Synthesis
Table 2 Market Players by Type
Table 3 Five Factors Driving Growth
Table 4 Three Factors Limiting Growth
Table 5 Global Market by Country/Region
Table 6 Global Market by Length
Table 7 Global Market by Application
Table 8 Global Market by Product
Table 9 <20 mer Market by Country
Table 10 21-50 mer Market by Country
Table 11 51-100 mer Market by Country
Table 12 >100 mer Market by Country
Table 13 Research Market by Country
Table 14 Diagnostics Market by Country
Table 15 Therapeutics Market by Country
Table 16 Data Market by Country
Table 17 Oligonucleotides Market by Country
Table 18 Instruments Market by Country
Table 19 Reagents Market by Country
Table 20 Clinical Lab Fee Schedule

Table of Figures

Figure 1 Global Health Spending
Figure 2 The Lab Test Pie
Figure 3 Phosphoramidites Structure
Figure 4 DNA/Oligonucleotide Synthetic Cycle
Figure 5 The Road to Diagnostics
Figure 6 Growth rates of Oligionucleotide Synthesis by Application
Figure 7 Market Size by Country
Figure 8 Global Market by Length - Base vs. Final Year
Figure 9 Length Market Base Year
Figure 10 Length Market Final Year
Figure 11 Length Share by Year
Figure 12 Length Segment Growth
Figure 13 Global Market by Application - Base vs. Final Year
Figure 14 Application Market Base Year
Figure 15 Application Market Final Year
Figure 16 Application Share by Year
Figure 17 Application Segment Growth
Figure 18 Global Market by Product - Base vs. Final Year
Figure 19 Product Market Base Year
Figure 20 Product Market Final Year
Figure 21 Product Share by Year
Figure 22 Product Segment Growth
Figure 23 Chart - <20 mer Market Growth
Figure 24 Chart 21-50 mer Market Growth
Figure 25 Chart - 51-100 mer Market Growth
Figure 26 Chart - >100 mer Market Growth
Figure 27 Chart Research Market Growth
Figure 28 Chart - Diagnostics Market Growth
Figure 29 Chart - Therapeutics market Growth
Figure 30 Chart - Data Market Growth
Figure 31 Chart Oligonucleotides Market Growth
Figure 32 Chart - Instruments Market Growth
Figure 33 Chart - Reagents Market Growth
Figure 34 Eurofins Price List
Figure 35 Hokkaido System Science Co. Price List
Figure 36 Biobasic Price List
Figure 37 Share of Pharma R&D by Country