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PUBLISHER: IMARC | PRODUCT CODE: 1451604

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PUBLISHER: IMARC | PRODUCT CODE: 1451604

Cell-free Protein Expression Market Report by Product, Method, Application, End User, and Region 2024-2032

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The global cell-free protein expression market size reached US$ 265.3 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 487.7 Million by 2032, exhibiting a growth rate (CAGR) of 6.86% during 2024-2032.

Cell-free protein expression (CFPE) refers to the production of desired recombinant proteins in solution using biomolecular translation machinery extracted from cells. It can be carried out using different cell lysates, such as E. coli, rabbit reticulocytes, wheat germ, insect cells, and mammalian cell-free protein expression systems. They are widely used in enzyme engineering, protein labeling, protein purification, protein-protein interaction, and high throughput production of mutants. CFPE is also used for analyzing components needed for protein stability, degradation, and folding. As compared to cell-based protein expression, cell-free protein expression is time efficient and convenient, allows the incorporation of non-natural amino acids, and provides enhanced stability and specificity.

Cell-free Protein Expression Market Trends:

The rapid advancement in biological sciences is one of the key factors driving the market growth. Cell-free protein expression is extensively used in the expansion of genetic code, assembly of viruses, and the synthesis of recombinant proteins for various biomolecular processes. Furthermore, the increasing technique utilization in the pharmaceutical industry for developing protein-based therapeutics, such as antibodies, antimicrobials, and cytokines, for treating cancer and infectious diseases is acting as another growth-inducing factor. Additionally, the integration of machine learning (ML) algorithms to improve protein production yield by optimizing the system for efficient prototyping and high-throughput experimentation is providing an impetus to market growth. Moreover, the introduction of novel processes to produce complex prokaryotic and eukaryotic proteins using a continuous-exchange cell-free (CECF) protein synthesis system is creating a positive outlook for the market. Other factors, including the widespread adoption of cell-free methods for biomanufacturing and prototyping, extensive research and development (R&D) activities in proteomics and genomics, and the rising adoption in the healthcare industry for diagnostic applications, such as pathogen sensing, inflammatory response, and personalized medicine, are supporting drive the market growth.

Key Market Segmentation:

IMARC Group provides an analysis of the key trends in each sub-segment of the global cell-free protein expression market report, along with forecasts at the global, regional and country level from 2024-2032. Our report has categorized the market based on product, method, application and end user.

Breakup by Product:

Expression Systems

E. coli Cell-free Protein Expression System

Wheat Germ Cell-free Protein Expression System

Rabbit Reticulocytes Cell-free Protein Expression System

Insect Cells Cell-free Protein Expression System

Human Cell-free Protein Expression System

Others

Reagents

Breakup by Method:

Transcription and Translation Systems

Translation Systems

Breakup by Application:

Enzyme Engineering

High Throughput Production

Protein Labeling

Protein-Protein Interaction

Protein Purification

Breakup by End User:

Pharmaceutical and Biotechnology Companies

Academic and Research Institutes

Others

Breakup by Region:

North America

United States

Canada

Asia-Pacific

China

Japan

India

South Korea

Australia

Indonesia

Others

Europe

Germany

France

United Kingdom

Italy

Spain

Russia

Others

Latin America

Brazil

Mexico

Others

Middle East and Africa

Competitive Landscape:

The competitive landscape of the industry has also been examined along with the profiles of the key players being Bioneer Corporation, biotechrabbit GmbH, Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.), CellFree Sciences Co. Ltd., Cube Biotech GmbH, GeneCopoeia Inc., Jena Bioscience GmbH, Merck KGaA, New England Biolabs, Promega Corporation, Takara Bio Inc. and Thermo Fisher Scientific Inc.

Key Questions Answered in This Report

  • 1. What was the size of the global cell-free protein expression market in 2023?
  • 2. What is the expected growth rate of the global cell-free protein expression market during 2024-2032?
  • 3. What are the key factors driving the global cell-free protein expression market?
  • 4. What has been the impact of COVID-19 on the global cell-free protein expression market?
  • 5. What is the breakup of the global cell-free protein expression market based on the product?
  • 6. What is the breakup of the global cell-free protein expression market based on the method?
  • 7. What is the breakup of the global cell-free protein expression market based on application?
  • 8. What is the breakup of the global cell-free protein expression market based on the end user?
  • 9. What are the key regions in the global cell-free protein expression market?
  • 10. Who are the key players/companies in the global cell-free protein expression market?
Product Code: SR112024A6288

Table of Contents

1 Preface

2 Scope and Methodology

  • 2.1 Objectives of the Study
  • 2.2 Stakeholders
  • 2.3 Data Sources
    • 2.3.1 Primary Sources
    • 2.3.2 Secondary Sources
  • 2.4 Market Estimation
    • 2.4.1 Bottom-Up Approach
    • 2.4.2 Top-Down Approach
  • 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

  • 4.1 Overview
  • 4.2 Key Industry Trends

5 Global Cell-free Protein Expression Market

  • 5.1 Market Overview
  • 5.2 Market Performance
  • 5.3 Impact of COVID-19
  • 5.4 Market Forecast

6 Market Breakup by Product

  • 6.1 Expression Systems
    • 6.1.1 Market Trends
    • 6.1.2 Key Segments
      • 6.1.2.1 E. coli Cell-free Protein Expression System
      • 6.1.2.2 Wheat Germ Cell-free Protein Expression System
      • 6.1.2.3 Rabbit Reticulocytes Cell-free Protein Expression System
      • 6.1.2.4 Insect Cells Cell-free Protein Expression System
      • 6.1.2.5 Human Cell-free Protein Expression System
      • 6.1.2.6 Others
    • 6.1.3 Market Forecast
  • 6.2 Reagents
    • 6.2.1 Market Trends
    • 6.2.2 Market Forecast

7 Market Breakup by Method

  • 7.1 Transcription and Translation Systems
    • 7.1.1 Market Trends
    • 7.1.2 Market Forecast
  • 7.2 Translation Systems
    • 7.2.1 Market Trends
    • 7.2.2 Market Forecast

8 Market Breakup by Application

  • 8.1 Enzyme Engineering
    • 8.1.1 Market Trends
    • 8.1.2 Market Forecast
  • 8.2 High Throughput Production
    • 8.2.1 Market Trends
    • 8.2.2 Market Forecast
  • 8.3 Protein Labeling
    • 8.3.1 Market Trends
    • 8.3.2 Market Forecast
  • 8.4 Protein-Protein Interaction
    • 8.4.1 Market Trends
    • 8.4.2 Market Forecast
  • 8.5 Protein Purification
    • 8.5.1 Market Trends
    • 8.5.2 Market Forecast

9 Market Breakup by End User

  • 9.1 Pharmaceutical and Biotechnology Companies
    • 9.1.1 Market Trends
    • 9.1.2 Market Forecast
  • 9.2 Academic and Research Institutes
    • 9.2.1 Market Trends
    • 9.2.2 Market Forecast
  • 9.3 Others
    • 9.3.1 Market Trends
    • 9.3.2 Market Forecast

10 Market Breakup by Region

  • 10.1 North America
    • 10.1.1 United States
      • 10.1.1.1 Market Trends
      • 10.1.1.2 Market Forecast
    • 10.1.2 Canada
      • 10.1.2.1 Market Trends
      • 10.1.2.2 Market Forecast
  • 10.2 Asia-Pacific
    • 10.2.1 China
      • 10.2.1.1 Market Trends
      • 10.2.1.2 Market Forecast
    • 10.2.2 Japan
      • 10.2.2.1 Market Trends
      • 10.2.2.2 Market Forecast
    • 10.2.3 India
      • 10.2.3.1 Market Trends
      • 10.2.3.2 Market Forecast
    • 10.2.4 South Korea
      • 10.2.4.1 Market Trends
      • 10.2.4.2 Market Forecast
    • 10.2.5 Australia
      • 10.2.5.1 Market Trends
      • 10.2.5.2 Market Forecast
    • 10.2.6 Indonesia
      • 10.2.6.1 Market Trends
      • 10.2.6.2 Market Forecast
    • 10.2.7 Others
      • 10.2.7.1 Market Trends
      • 10.2.7.2 Market Forecast
  • 10.3 Europe
    • 10.3.1 Germany
      • 10.3.1.1 Market Trends
      • 10.3.1.2 Market Forecast
    • 10.3.2 France
      • 10.3.2.1 Market Trends
      • 10.3.2.2 Market Forecast
    • 10.3.3 United Kingdom
      • 10.3.3.1 Market Trends
      • 10.3.3.2 Market Forecast
    • 10.3.4 Italy
      • 10.3.4.1 Market Trends
      • 10.3.4.2 Market Forecast
    • 10.3.5 Spain
      • 10.3.5.1 Market Trends
      • 10.3.5.2 Market Forecast
    • 10.3.6 Russia
      • 10.3.6.1 Market Trends
      • 10.3.6.2 Market Forecast
    • 10.3.7 Others
      • 10.3.7.1 Market Trends
      • 10.3.7.2 Market Forecast
  • 10.4 Latin America
    • 10.4.1 Brazil
      • 10.4.1.1 Market Trends
      • 10.4.1.2 Market Forecast
    • 10.4.2 Mexico
      • 10.4.2.1 Market Trends
      • 10.4.2.2 Market Forecast
    • 10.4.3 Others
      • 10.4.3.1 Market Trends
      • 10.4.3.2 Market Forecast
  • 10.5 Middle East and Africa
    • 10.5.1 Market Trends
    • 10.5.2 Market Breakup by Country
    • 10.5.3 Market Forecast

11 SWOT Analysis

  • 11.1 Overview
  • 11.2 Strengths
  • 11.3 Weaknesses
  • 11.4 Opportunities
  • 11.5 Threats

12 Value Chain Analysis

13 Porters Five Forces Analysis

  • 13.1 Overview
  • 13.2 Bargaining Power of Buyers
  • 13.3 Bargaining Power of Suppliers
  • 13.4 Degree of Competition
  • 13.5 Threat of New Entrants
  • 13.6 Threat of Substitutes

14 Price Analysis

15 Competitive Landscape

  • 15.1 Market Structure
  • 15.2 Key Players
  • 15.3 Profiles of Key Players
    • 15.3.1 Bioneer Corporation
      • 15.3.1.1 Company Overview
      • 15.3.1.2 Product Portfolio
      • 15.3.1.3 Financials
    • 15.3.2 biotechrabbit GmbH
      • 15.3.2.1 Company Overview
      • 15.3.2.2 Product Portfolio
    • 15.3.3 Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.)
      • 15.3.3.1 Company Overview
      • 15.3.3.2 Product Portfolio
    • 15.3.4 CellFree Sciences Co. Ltd.
      • 15.3.4.1 Company Overview
      • 15.3.4.2 Product Portfolio
    • 15.3.5 Cube Biotech GmbH
      • 15.3.5.1 Company Overview
      • 15.3.5.2 Product Portfolio
    • 15.3.6 GeneCopoeia Inc.
      • 15.3.6.1 Company Overview
      • 15.3.6.2 Product Portfolio
    • 15.3.7 Jena Bioscience GmbH
      • 15.3.7.1 Company Overview
      • 15.3.7.2 Product Portfolio
    • 15.3.8 Merck KGaA
      • 15.3.8.1 Company Overview
      • 15.3.8.2 Product Portfolio
      • 15.3.8.3 Financials
      • 15.3.8.4 SWOT Analysis
    • 15.3.9 New England Biolabs
      • 15.3.9.1 Company Overview
      • 15.3.9.2 Product Portfolio
    • 15.3.10 Promega Corporation
      • 15.3.10.1 Company Overview
      • 15.3.10.2 Product Portfolio
    • 15.3.11 Takara Bio Inc.
      • 15.3.11.1 Company Overview
      • 15.3.11.2 Product Portfolio
      • 15.3.11.3 Financials
    • 15.3.12 Thermo Fisher Scientific Inc.
      • 15.3.12.1 Company Overview
      • 15.3.12.2 Product Portfolio
      • 15.3.12.3 Financials
      • 15.3.12.4 SWOT Analysis
Product Code: SR112024A6288

List of Figures

  • Figure 1: Global: Cell-free Protein Expression Market: Major Drivers and Challenges
  • Figure 2: Global: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018-2023
  • Figure 3: Global: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 4: Global: Cell-free Protein Expression Market: Breakup by Product (in %), 2023
  • Figure 5: Global: Cell-free Protein Expression Market: Breakup by Method (in %), 2023
  • Figure 6: Global: Cell-free Protein Expression Market: Breakup by Application (in %), 2023
  • Figure 7: Global: Cell-free Protein Expression Market: Breakup by End User (in %), 2023
  • Figure 8: Global: Cell-free Protein Expression Market: Breakup by Region (in %), 2023
  • Figure 9: Global: Cell-free Protein Expression (Expression Systems) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 10: Global: Cell-free Protein Expression (Expression Systems) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 11: Global: Cell-free Protein Expression (Reagents) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 12: Global: Cell-free Protein Expression (Reagents) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 13: Global: Cell-free Protein Expression (Transcription and Translation Systems) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 14: Global: Cell-free Protein Expression (Transcription and Translation Systems) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 15: Global: Cell-free Protein Expression (Translation Systems) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 16: Global: Cell-free Protein Expression (Translation Systems) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 17: Global: Cell-free Protein Expression (Enzyme Engineering) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 18: Global: Cell-free Protein Expression (Enzyme Engineering) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 19: Global: Cell-free Protein Expression (High Throughput Production) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 20: Global: Cell-free Protein Expression (High Throughput Production) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 21: Global: Cell-free Protein Expression (Protein Labeling) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 22: Global: Cell-free Protein Expression (Protein Labeling) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 23: Global: Cell-free Protein Expression (Protein-Protein Interaction) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 24: Global: Cell-free Protein Expression (Protein-Protein Interaction) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 25: Global: Cell-free Protein Expression (Protein Purification) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 26: Global: Cell-free Protein Expression (Protein Purification) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 27: Global: Cell-free Protein Expression (Pharmaceutical and Biotechnology Companies) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 28: Global: Cell-free Protein Expression (Pharmaceutical and Biotechnology Companies) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 29: Global: Cell-free Protein Expression (Academic and Research Institutes) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 30: Global: Cell-free Protein Expression (Academic and Research Institutes) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 31: Global: Cell-free Protein Expression (Other End Users) Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 32: Global: Cell-free Protein Expression (Other End Users) Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 33: North America: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 34: North America: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 35: United States: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 36: United States: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 37: Canada: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 38: Canada: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 39: Asia-Pacific: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 40: Asia-Pacific: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 41: China: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 42: China: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 43: Japan: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 44: Japan: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 45: India: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 46: India: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 47: South Korea: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 48: South Korea: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 49: Australia: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 50: Australia: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 51: Indonesia: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 52: Indonesia: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 53: Others: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 54: Others: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 55: Europe: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 56: Europe: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 57: Germany: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 58: Germany: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 59: France: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 60: France: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 61: United Kingdom: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 62: United Kingdom: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 63: Italy: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 64: Italy: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 65: Spain: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 66: Spain: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 67: Russia: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 68: Russia: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 69: Others: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 70: Others: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 71: Latin America: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 72: Latin America: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 73: Brazil: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 74: Brazil: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 75: Mexico: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 76: Mexico: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 77: Others: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 78: Others: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 79: Middle East and Africa: Cell-free Protein Expression Market: Sales Value (in Million US$), 2018 & 2023
  • Figure 80: Middle East and Africa: Cell-free Protein Expression Market: Breakup by Country (in %), 2023
  • Figure 81: Middle East and Africa: Cell-free Protein Expression Market Forecast: Sales Value (in Million US$), 2024-2032
  • Figure 82: Global: Cell-free Protein Expression Industry: SWOT Analysis
  • Figure 83: Global: Cell-free Protein Expression Industry: Value Chain Analysis
  • Figure 84: Global: Cell-free Protein Expression Industry: Porter's Five Forces Analysis

List of Tables

  • Table 1: Global: Cell-free Protein Expression Market: Key Industry Highlights, 2023 & 2032
  • Table 2: Global: Cell-free Protein Expression Market Forecast: Breakup by Product (in Million US$), 2024-2032
  • Table 3: Global: Cell-free Protein Expression Market Forecast: Breakup by Method (in Million US$), 2024-2032
  • Table 4: Global: Cell-free Protein Expression Market Forecast: Breakup by Application (in Million US$), 2024-2032
  • Table 5: Global: Cell-free Protein Expression Market Forecast: Breakup by End User (in Million US$), 2024-2032
  • Table 6: Global: Cell-free Protein Expression Market Forecast: Breakup by Region (in Million US$), 2024-2032
  • Table 7: Global: Cell-free Protein Expression Market: Competitive Structure
  • Table 8: Global: Cell-free Protein Expression Market: Key Players
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