PUBLISHER: Knowledge Sourcing Intelligence | PRODUCT CODE: 1410090
PUBLISHER: Knowledge Sourcing Intelligence | PRODUCT CODE: 1410090
The global scaffold technology market is estimated to grow at a CAGR of 13.57% during the forecast period.
Scaffold technology is used especially in tissue engineering, regenerative medicine, and drug discovery. Scaffolds are three-dimensional constructs that give mechanical support and a favourable environment for cell development in the field of tissue engineering. They present potential solutions for tissue regeneration and repair. Made of a variety of materials, these scaffolds imitate the extracellular matrix found in nature, providing a surface on which cells may cling and multiply. Scaffold technology is used in drug development to generate molecular frameworks that may be altered to produce a variety of compounds for testing, which expedites the process of finding new drugs.
Major growth drivers for the scaffold technology market are the increased need for 3D cellular models for use in biological research and translational studies. The scaffold technology market is expanding as the 3D cell culture is rising due to difficulties in the drug development process. The study of virology and epidemiology, the creation of in vitro model systems, and the search for effective anti-infective therapies all make substantial use of tissue engineering which fuels the scaffold technology market growth.
For 3D cell culture, scaffolds are significantly used. Scaffolds enable the movement of oxygen, nutrients, and waste because of their porosity. Cells can therefore multiply and move around the scaffold web before adhering to it. The maturing cells interact with one another as they grow and eventually transform into structures that are connected to the tissues from which they originally came. This growing application of scaffolding in 3D cell culture is expected to fuel the scaffold technology market growth.
Technological breakthroughs in scaffolding have influenced revolutionary advances in regenerative medicine and tissue engineering. The creation of scaffolds has been transformed by the combination of 3D printing with bioprinting, which allows for exact control over the arrangement of cells and structure. These advancements are major growth drivers for the scaffold technology market. Solvent casting, solution blow spinning, particle leaching, self-assembly, gas foaming, fiber mesh, and lithography are some of the processes included in scaffold technology.
Several biocompatible polymers that have received FDA approval have been established to create a variety of 3D scaffolds to treat cancer recurrence, which is a major driver for the scaffold technology market growth. For choosing a polymer, the type of tumour microenvironment, metastasis, chemo medicines, and immunotherapeutics are analyzed for various qualities such as high surface volume, high porosity, and tuneable mechanical properties. Moreover, 3D scaffolds are of interest for cancer immunotherapy and are further upsurging the scaffold technology market growth.
The use of nano-fiber scaffolds is expanding due to their growing use in tissue engineering and regeneration applications. For instance, scientists around the globe are focusing on research related to nanofiber scaffold usage in the creation of nerve tissue. Nano-sized structures that can serve as an extracellular matrix for cellular transformation are made using techniques like electrospinning. Electrospinning provides several benefits such as simplicity of use, affordability, and high flexibility, which can accelerate the scaffold technology market growth.
The scaffold technology market is anticipated to grow due to various government initiatives. For instance, in June 2023, the Indian Drugs Controller gave their permission to the first locally created tissue engineering scaffold made from mammalian organs, a Class D biomedical device that may quickly and affordably treat skin lesions with little scarring. The Department of Science and Technology (DST) and Sree Chira Triunal Institute for Medical Sciences and Technology, collaborated to meet all the legal requirements to form the Central Drugs Standard Control Organization.
The scaffold technology market is predicted to grow at a steady pace in North America. This can be attributed to a rise in research on stem cells and regenerative medicine, increased funding for expanding the applications of these technologies, and a well-established healthcare system. Furthermore, researchers have also improved 3D micro scaffold technology, which helps reprogrammed neural stem cells and supports connections between neurons. Instead of injecting individual cells, these networks exhibited greater brain survival in mice. Additionally, stem cell biologists and biomaterial specialists collaborated in their recent work supported by the National Institute of Biomedical Imaging and Bioengineering.
For tissue regeneration, many businesses are creating novel 3D bio-printed customized scaffolds. For instance, 3D Systems and United Therapeutics Corporation collaborated to create cutting-edge 3D-printed organ technology in June 2022. Moreover, nanofiber scaffolds are gaining popularity because of their high surface area-to-volume ratio and capacity to replicate the fibrous structure of the extracellular matrix in nature. Additionally, in November 2022, Gelomics and Rousselot announced a cobranding partnership that used Gelomics' LunaGel 3D Tissue Culture System and Rousselot Biomedical's X-Pure GelMA (gelatin methacryloyl) extracellular matrix.