NORTH AMERICA GLUCAGON-LIKE PEPTIDE-1 (GLP-1) AGONISTS MARKET - GROWTH, TRENDS, COVID-19 IMPACT, AND FORECASTS (2022 - 2027)

Key Highlights

• GLP-1 drugs are also known as "Incretin mimetics," a hormone that stimulates insulin secretion in response to meals.
• The GLP-1s are considered an adjunct to diet and exercise, to improve glycemic control in adults with type-2 diabetes mellitus.
• Patients with type-2 diabetes have diminished insulin release in response to meals and it is speculated that they may have defects in the release or action of their incretin hormones.
• Increasing diabetes prevalence in established and emerging countries is expected to drive the market. The increase in the diabetic population over the years is due to the overall effect of individual-level factors, like increasing median age and health factors, including increasing obesity and inactivity levels among people.

Key Market Trends

Growing Type-2 Diabetes Population in North America

• It is estimated that within the region, the age-adjusted prevalence of diabetes for the United States is around 9.2%, and is around 7.9% for Canada and 12.6% for Mexico.
• The economic impact is also significant. Healthcare spending due to diabetes was estimated to be USD 426.8 million in 2017, the highest of all IDF regions.
• The North American region suffers from a high burden of diabetes, and its subsequent adverse health and economic consequences. The disease should be viewed as a serious threat, not just from a public health perspective, but also from a development perspective.
• With risk factors, such as obesity increasing, and progressively aging populations, the diabetes epidemic is growing, especially in low- and middle-income countries of the region. It is one of the most common chronic diseases in Canada.

The US to Dominate the Market during the Forecast Period

• Among the countries in North America, the United States dominates the market, owing to the high prevalence of diabetes and obesity in the region, because of a sedentary lifestyle.
• The cost factor is the primary concern in the United States, where almost 50% of the market share for manufacturers is from the United States itself. Victoza has the highest market share in the country

Competitive Landscape

• The North America GLP-1 market is consolidated, with four major manufacturers holding a presence in the North American region.
• Currently, no generic versions of the GLP-1s are available in the market, since the drugs are patent protected. However, Teva confirmed generic Victoza and announced that it had filed an abbreviated new drug application (ANDA) with the US Food and Drug Administration (FDA), seeking approval to market the generic version of Novo Nordisk's Victoza® (liraglutide) injection, in the United States.

Additional Benefits:

• The market estimate (ME) sheet in Excel format
• 3 months of analyst support