U.S. Plasmid Purification Market Size, Share, Trends, Industry Analysis Report By Product & Service (Products, Services), By Grade, By Application, By End Use

Description

List of Tables

The U.S. plasmid purification market size is expected to reach USD 2,033.44 Million by 2034, according to a new study by Polaris Market Research. The report "U.S. Plasmid Purification Market Size, Share, Trends, Industry Analysis Report By Product & Service (Products, Services), By Grade, By Application, By End Use - Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.

Plasmid purification is a core process in molecular biology, focusing on the isolation and purification of plasmid DNA from bacterial cells. This essential procedure removes unwanted cellular components such as proteins, RNA, and genomic DNA to produce a highly pure and concentrated sample of plasmid DNA. The quality and purity of this DNA are critical for a wide range of downstream applications, including genetic engineering, cloning, and the production of therapeutic proteins. Efficient purification methods are key to ensuring the success and reliability of these processes in both research and commercial settings.

The U.S. plasmid purification market is experiencing steady growth driven by several factors such as the country's strong biotech and pharmaceutical industries and significant funding for biomedical research. A key trend is the increasing demand for high-purity, transfection-grade plasmids required for advanced therapies like gene therapy and DNA vaccines. This demand is leading to a shift towards more automated and scalable purification methods. The market also sees a strong presence from both product providers, who offer kits and instruments, and service providers, who handle large-scale manufacturing and purification. As the focus on personalized medicine and genetic research continues to grow, the need for reliable plasmid purification solutions will remain a central theme in the market's future.

U.S. Plasmid Purification Market Report Highlights:

By product & service, the products segment held the largest share in 2024, driven by the widespread and constant need for purification kits, reagents, and instruments in research and development activities across the U.S.

Based on grade, the molecular grade segment held the largest share in 2024. This is because molecular grade plasmids are the preferred choice for a vast number of foundational research applications, such as basic cloning and gene expression studies, in academic and early-stage biotech labs throughout the country.

In terms of application, the cloning and protein expression segment held the largest share in 2024. This is due to its fundamental role in a broad spectrum of research and industrial activities, including the development of new diagnostic tools and the production of therapeutic proteins, which are a cornerstone of modern biotechnology in the U.S.

By end use, the academic and research institutes segment held the largest share in 2024. These institutions, including university labs and government research centers, are the primary drivers of foundational research in molecular biology and genetic engineering, creating a consistently high demand for plasmid purification products and services.

A few key players in the market include Thermo Fisher Scientific, QIAGEN, Promega Corporation, Merck KGaA, Zymo Research, New England Biolabs, Takara Bio Inc., Agilent Technologies Inc., GenScript, Aldevron (Danaher), and Bio-Rad Laboratories, Inc.

Polaris Market Research has segmented the U.S. plasmid purification market report based on product & service, grade, application, and end use:

By Product & Service Outlook (Revenue - USD Million, 2020-2034)

Products

Instruments

Kits & Reagents

Services

By Grade Outlook (Revenue - USD Million, 2020-2034)

Molecular Grade

Transfection Grade

By Application Outlook (Revenue - USD Million, 2020-2034)

Cloning & Protein Expression

Transfection & Gene Editing

Others

By End-use Outlook (Revenue - USD Million, 2020-2034)

Pharmaceutical & Biotechnology Companies

Academic & Research Institutes

Contract Research Organizations

Product Code: PM6250

1. Introduction

1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
1.2. Stakeholders

2. Executive Summary

2.1. Market Highlights

3. Research Methodology

3.1. Overview
- 3.1.1. Data Mining
3.2. Data Sources
- 3.2.1. Primary Sources
- 3.2.2. Secondary Sources

4. U.S. Plasmid Purification Market Insights

4.1. U.S. Plasmid Purification Market - Market Snapshot
4.2. U.S. Plasmid Purification Market Dynamics
- 4.2.1. Drivers and Opportunities
  - 4.2.1.1. Growing Demand for Gene Therapy and DNA Vaccines
  - 4.2.1.2. Rising Funding for Biomedical Research
- 4.2.2. Restraints and Challenges
  - 4.2.2.1. Cost and regulatory burdens even domestically
4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. U.S. Plasmid Purification Market Trends
4.6. Value Chain Analysis
4.7. COVID-19 Impact Analysis

5. U.S. Plasmid Purification Market, by Product & Service

5.1. Key Findings
5.2. Introduction
- 5.2.1. U.S. Plasmid Purification Market, by Product & Service, 2020-2034 (USD Million)
5.3. Products
- 5.3.1. U.S. Plasmid Purification Market, by Products, by Region, 2020-2034 (USD Million)
- 5.3.2. Instruments
- 5.3.3. Kits & Reagents
5.4. Services
- 5.4.1. U.S. Plasmid Purification Market, by Services, by Region, 2020-2034 (USD Million)

6. U.S. Plasmid Purification Market, by Grade

6.1. Key Findings
6.2. Introduction
- 6.2.1. U.S. Plasmid Purification Market, by Grade, 2020-2034 (USD Million)
6.3. Molecular Grade
- 6.3.1. U.S. Plasmid Purification Market, by Molecular Grade, by Region, 2020-2034 (USD Million)
6.4. Transfection Grade
- 6.4.1. U.S. Plasmid Purification Market, by Transfection Grade, by Region, 2020-2034 (USD Million)

7. U.S. Plasmid Purification Market, by Application

7.1. Key Findings
7.2. Introduction
- 7.2.1. U.S. Plasmid Purification Market, by Application, 2020-2034 (USD Million)
7.3. Cloning & Protein Expression
- 7.3.1. U.S. Plasmid Purification Market, by Cloning & Protein Expression, by Region, 2020-2034 (USD Million)
7.4. Transfection & Gene Editing
- 7.4.1. U.S. Plasmid Purification Market, by Transfection & Gene Editing, by Region, 2020-2034 (USD Million)
7.5. Others
- 7.5.1. U.S. Plasmid Purification Market, by Others, by Region, 2020-2034 (USD Million)

8. U.S. Plasmid Purification Market, by End-use

8.1. Key Findings
8.2. Introduction
- 8.2.1. U.S. Plasmid Purification Market, by End-use, 2020-2034 (USD Million)
8.3. Pharmaceutical & Biotechnology Companies
- 8.3.1. U.S. Plasmid Purification Market, by Pharmaceutical & Biotechnology Companies, by Region, 2020-2034 (USD Million)
8.4. Academic & Research Institutes
- 8.4.1. U.S. Plasmid Purification Market, by Academic & Research Institutes, by Region, 2020-2034 (USD Million)
8.5. Contract Research Organizations
- 8.5.1. U.S. Plasmid Purification Market, by Contract Research Organizations, by Region, 2020-2034 (USD Million)

9. Competitive Landscape

9.1. Expansion and Acquisition Analysis
- 9.1.1. Expansion
- 9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions

10. Company Profiles

10.1. Agilent Technologies, Inc.
- 10.1.1. Company Overview
- 10.1.2. Financial Performance
- 10.1.3. Product Benchmarking
- 10.1.4. Recent Development
10.2. Aldevron (Danaher Corporation)
- 10.2.1. Company Overview
- 10.2.2. Financial Performance
- 10.2.3. Product Benchmarking
- 10.2.4. Recent Development
10.3. GenScript
- 10.3.1. Company Overview
- 10.3.2. Financial Performance
- 10.3.3. Product Benchmarking
- 10.3.4. Recent Development
10.4. Merck KGaA
- 10.4.1. Company Overview
- 10.4.2. Financial Performance
- 10.4.3. Product Benchmarking
- 10.4.4. Recent Development
10.5. New England Biolabs, Inc.
- 10.5.1. Company Overview
- 10.5.2. Financial Performance
- 10.5.3. Product Benchmarking
- 10.5.4. Recent Development
10.6. Promega Corporation
- 10.6.1. Company Overview
- 10.6.2. Financial Performance
- 10.6.3. Product Benchmarking
- 10.6.4. Recent Development
10.7. QIAGEN
- 10.7.1. Company Overview
- 10.7.2. Financial Performance
- 10.7.3. Product Benchmarking
- 10.7.4. Recent Development
10.8. Takara Bio Inc.
- 10.8.1. Company Overview
- 10.8.2. Financial Performance
- 10.8.3. Product Benchmarking
- 10.8.4. Recent Development
10.9. Thermo Fisher Scientific, Inc.
- 10.9.1. Company Overview
- 10.9.2. Financial Performance
- 10.9.3. Product Benchmarking
- 10.9.4. Recent Development
10.10. Zymo Research
- 10.10.1. Company Overview
- 10.10.2. Financial Performance
- 10.10.3. Product Benchmarking
- 10.10.4. Recent Development