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PUBLISHER: QYResearch | PRODUCT CODE: 1872194

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PUBLISHER: QYResearch | PRODUCT CODE: 1872194

Plasminogen - Global Market Share and Ranking, Overall Sales and Demand Forecast 2025-2031

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The global market for Plasminogen was estimated to be worth US$ 11.8 million in 2024 and is forecast to a readjusted size of US$ 118 million by 2031 with a CAGR of 39.5% during the forecast period 2025-2031.

Plasminogen, the proenzyme of the fibrinolytically active enzyme plasmin, is a single chain glycoprotein with a molecular weight of about 90,000-94,000 Da (2). Various isoelectric forms exist and can be separated by means of isoelectric focusing (IEF). The complete amino acid sequence contains 790 amino acids. Native plasminogen (glu-plasminogen) has a N-terminal glutamic acid group. Partial plasma proteolysis gives rise to a molecule with N-terminal lysine (lysplasminogen). Currently, the product has obtained the designation of orphan drug by the US Food and Drug Administration (FDA) and by the European Medicines Agency (EMA). In 2021, U.S. Food and Drug Administration approved Ryplazim (plasminogen, human-tvmh) for the treatment of patients with plasminogen deficiency type 1, also referred to as hypoplasminogenemia, a disorder that can impair normal tissue and organ function and may lead to blindness. The report mainly targeting the research status, predicted competitive landscape, market potential and future trends of plasminogen market.

The plasminogen market is primarily driven by its critical role in fibrinolysis and thrombolytic therapy, where it is used to dissolve blood clots and treat related conditions such as deep vein thrombosis, pulmonary embolism, and myocardial infarction. As the prevalence of cardiovascular diseases and clotting disorders continues to rise globally, demand for plasminogen-based therapies is growing steadily. Additionally, the use of plasminogen in rare diseases such as plasminogen deficiency, which can cause severe tissue damage and vision loss, further strengthens the market's importance in specialized treatment areas.

Beyond therapeutic applications, the plasminogen market is also supported by research activities focused on wound healing, tissue repair, and ocular health. Biopharmaceutical advancements and innovative drug delivery systems are expanding the scope of plasminogen-based products. However, the market faces challenges such as the high cost of therapies, limited availability of plasma-derived products, and stringent regulatory approval processes. Despite these hurdles, ongoing clinical trials and growing awareness of fibrinolytic agents are expected to create new opportunities for expansion in the coming years.

This report aims to provide a comprehensive presentation of the global market for Plasminogen, focusing on the total sales revenue, key companies market share and ranking, together with an analysis of Plasminogen by region & country, by Type, and by Application.

The Plasminogen market size, estimations, and forecasts are provided in terms of sales revenue ($ millions), considering 2024 as the base year, with history and forecast data for the period from 2020 to 2031. With both quantitative and qualitative analysis, to help readers develop business/growth strategies, assess the market competitive situation, analyze their position in the current marketplace, and make informed business decisions regarding Plasminogen.

Market Segmentation

By Company

  • Kedrion(Prometic)

Segment by Type

  • Intravenous Injection
  • Eye Drops

Segment by Application

  • Ligneous Conjunctivitis
  • Diabetic Foot
  • Wound Healing
  • Others

By Region

  • North America
    • United States
    • Canada
  • Asia-Pacific
    • China
    • Japan
    • South Korea
    • Southeast Asia
    • India
    • Australia
    • Rest of Asia-Pacific
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Netherlands
    • Nordic Countries
    • Rest of Europe
  • Latin America
    • Mexico
    • Brazil
    • Rest of Latin America
  • Middle East & Africa
    • Turkey
    • Saudi Arabia
    • UAE
    • Rest of MEA

Chapter Outline

Chapter 1: Introduces the report scope of the report, global total market size. This chapter also provides the market dynamics, latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 2: Detailed analysis of Plasminogen company competitive landscape, revenue market share, latest development plan, merger, and acquisition information, etc.

Chapter 3: Provides the analysis of various market segments by Type, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 4: Provides the analysis of various market segments by Application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 5: Revenue of Plasminogen in regional level. It provides a quantitative analysis of the market size and development potential of each region and introduces the market development, future development prospects, market space, and market size of each country in the world.

Chapter 6: Revenue of Plasminogen in country level. It provides sigmate data by Type, and by Application for each country/region.

Chapter 7: Provides profiles of key players, introducing the basic situation of the main companies in the market in detail, including product revenue, gross margin, product introduction, recent development, etc.

Chapter 8: Analysis of industrial chain, including the upstream and downstream of the industry.

Chapter 9: Conclusion.

Table of Contents

1 Market Overview

  • 1.1 Plasminogen Product Introduction
  • 1.2 Global Plasminogen Market Size Forecast (2020-2031)
  • 1.3 Plasminogen Market Trends & Drivers
    • 1.3.1 Plasminogen Industry Trends
    • 1.3.2 Plasminogen Market Drivers & Opportunity
    • 1.3.3 Plasminogen Market Challenges
    • 1.3.4 Plasminogen Market Restraints
  • 1.4 Assumptions and Limitations
  • 1.5 Study Objectives
  • 1.6 Years Considered

2 Competitive Analysis by Company

  • 2.1 Global Plasminogen Players Revenue Ranking (2024)
  • 2.2 Global Plasminogen Revenue by Company (2020-2025)
  • 2.3 Key Companies Plasminogen Manufacturing Base Distribution and Headquarters
  • 2.4 Key Companies Plasminogen Product Offered
  • 2.5 Key Companies Time to Begin Mass Production of Plasminogen
  • 2.6 Plasminogen Market Competitive Analysis
    • 2.6.1 Plasminogen Market Concentration Rate (2020-2025)
    • 2.6.2 Global 5 and 10 Largest Companies by Plasminogen Revenue in 2024
    • 2.6.3 Global Top Companies by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Plasminogen as of 2024)
  • 2.7 Mergers & Acquisitions, Expansion

3 Segmentation by Type

  • 3.1 Introduction by Type
    • 3.1.1 Intravenous Injection
    • 3.1.2 Eye Drops
  • 3.2 Global Plasminogen Sales Value by Type
    • 3.2.1 Global Plasminogen Sales Value by Type (2020 VS 2024 VS 2031)
    • 3.2.2 Global Plasminogen Sales Value, by Type (2020-2031)
    • 3.2.3 Global Plasminogen Sales Value, by Type (%) (2020-2031)

4 Segmentation by Application

  • 4.1 Introduction by Application
    • 4.1.1 Ligneous Conjunctivitis
    • 4.1.2 Diabetic Foot
    • 4.1.3 Wound Healing
    • 4.1.4 Others
  • 4.2 Global Plasminogen Sales Value by Application
    • 4.2.1 Global Plasminogen Sales Value by Application (2020 VS 2024 VS 2031)
    • 4.2.2 Global Plasminogen Sales Value, by Application (2020-2031)
    • 4.2.3 Global Plasminogen Sales Value, by Application (%) (2020-2031)

5 Segmentation by Region

  • 5.1 Global Plasminogen Sales Value by Region
    • 5.1.1 Global Plasminogen Sales Value by Region: 2020 VS 2024 VS 2031
    • 5.1.2 Global Plasminogen Sales Value by Region (2020-2025)
    • 5.1.3 Global Plasminogen Sales Value by Region (2026-2031)
    • 5.1.4 Global Plasminogen Sales Value by Region (%), (2020-2031)
  • 5.2 North America
    • 5.2.1 North America Plasminogen Sales Value, 2020-2031
    • 5.2.2 North America Plasminogen Sales Value by Country (%), 2024 VS 2031
  • 5.3 Europe
    • 5.3.1 Europe Plasminogen Sales Value, 2020-2031
    • 5.3.2 Europe Plasminogen Sales Value by Country (%), 2024 VS 2031
  • 5.4 Asia Pacific
    • 5.4.1 Asia Pacific Plasminogen Sales Value, 2020-2031
    • 5.4.2 Asia Pacific Plasminogen Sales Value by Region (%), 2024 VS 2031
  • 5.5 South America
    • 5.5.1 South America Plasminogen Sales Value, 2020-2031
    • 5.5.2 South America Plasminogen Sales Value by Country (%), 2024 VS 2031
  • 5.6 Middle East & Africa
    • 5.6.1 Middle East & Africa Plasminogen Sales Value, 2020-2031
    • 5.6.2 Middle East & Africa Plasminogen Sales Value by Country (%), 2024 VS 2031

6 Segmentation by Key Countries/Regions

  • 6.1 Key Countries/Regions Plasminogen Sales Value Growth Trends, 2020 VS 2024 VS 2031
  • 6.2 Key Countries/Regions Plasminogen Sales Value, 2020-2031
  • 6.3 United States
    • 6.3.1 United States Plasminogen Sales Value, 2020-2031
    • 6.3.2 United States Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.3.3 United States Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.4 Europe
    • 6.4.1 Europe Plasminogen Sales Value, 2020-2031
    • 6.4.2 Europe Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.4.3 Europe Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.5 China
    • 6.5.1 China Plasminogen Sales Value, 2020-2031
    • 6.5.2 China Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.5.3 China Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.6 Japan
    • 6.6.1 Japan Plasminogen Sales Value, 2020-2031
    • 6.6.2 Japan Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.6.3 Japan Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.7 South Korea
    • 6.7.1 South Korea Plasminogen Sales Value, 2020-2031
    • 6.7.2 South Korea Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.7.3 South Korea Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.8 Southeast Asia
    • 6.8.1 Southeast Asia Plasminogen Sales Value, 2020-2031
    • 6.8.2 Southeast Asia Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.8.3 Southeast Asia Plasminogen Sales Value by Application, 2024 VS 2031
  • 6.9 India
    • 6.9.1 India Plasminogen Sales Value, 2020-2031
    • 6.9.2 India Plasminogen Sales Value by Type (%), 2024 VS 2031
    • 6.9.3 India Plasminogen Sales Value by Application, 2024 VS 2031

7 Company Profiles

  • 7.1 Kedrion(Prometic)
    • 7.1.1 Kedrion(Prometic) Profile
    • 7.1.2 Kedrion(Prometic) Main Business
    • 7.1.3 Kedrion(Prometic) Plasminogen Products, Services and Solutions
    • 7.1.4 Kedrion(Prometic) Plasminogen Revenue (US$ Million) & (2020-2025)
    • 7.1.5 Kedrion(Prometic) Recent Developments

8 Industry Chain Analysis

  • 8.1 Plasminogen Industrial Chain
  • 8.2 Plasminogen Upstream Analysis
    • 8.2.1 Key Raw Materials
    • 8.2.2 Raw Materials Key Suppliers
    • 8.2.3 Manufacturing Cost Structure
  • 8.3 Midstream Analysis
  • 8.4 Downstream Analysis (Customers Analysis)
  • 8.5 Sales Model and Sales Channels
    • 8.5.1 Plasminogen Sales Model
    • 8.5.2 Sales Channel
    • 8.5.3 Plasminogen Distributors

9 Research Findings and Conclusion

10 Appendix

  • 10.1 Research Methodology
    • 10.1.1 Methodology/Research Approach
      • 10.1.1.1 Research Programs/Design
      • 10.1.1.2 Market Size Estimation
      • 10.1.1.3 Market Breakdown and Data Triangulation
    • 10.1.2 Data Source
      • 10.1.2.1 Secondary Sources
      • 10.1.2.2 Primary Sources
  • 10.2 Author Details
  • 10.3 Disclaimer

List of Tables

  • Table 1. Plasminogen Market Trends
  • Table 2. Plasminogen Market Drivers & Opportunity
  • Table 3. Plasminogen Market Challenges
  • Table 4. Plasminogen Market Restraints
  • Table 5. Global Plasminogen Revenue by Company (2020-2025) & (US$ Million)
  • Table 6. Global Plasminogen Revenue Market Share by Company (2020-2025)
  • Table 7. Key Companies Plasminogen Manufacturing Base Distribution and Headquarters
  • Table 8. Key Companies Plasminogen Product Type
  • Table 9. Key Companies Time to Begin Mass Production of Plasminogen
  • Table 10. Global Plasminogen Companies Market Concentration Ratio (CR5 and HHI)
  • Table 11. Global Top Companies by Company Type (Tier 1, Tier 2, and Tier 3) & (based on the Revenue in Plasminogen as of 2024)
  • Table 12. Mergers & Acquisitions, Expansion Plans
  • Table 13. Global Plasminogen Sales Value by Type: 2020 VS 2024 VS 2031 (US$ Million)
  • Table 14. Global Plasminogen Sales Value by Type (2020-2025) & (US$ Million)
  • Table 15. Global Plasminogen Sales Value by Type (2026-2031) & (US$ Million)
  • Table 16. Global Plasminogen Sales Market Share in Value by Type (2020-2025)
  • Table 17. Global Plasminogen Sales Market Share in Value by Type (2026-2031)
  • Table 18. Global Plasminogen Sales Value by Application: 2020 VS 2024 VS 2031 (US$ Million)
  • Table 19. Global Plasminogen Sales Value by Application (2020-2025) & (US$ Million)
  • Table 20. Global Plasminogen Sales Value by Application (2026-2031) & (US$ Million)
  • Table 21. Global Plasminogen Sales Market Share in Value by Application (2020-2025)
  • Table 22. Global Plasminogen Sales Market Share in Value by Application (2026-2031)
  • Table 23. Global Plasminogen Sales Value by Region, (2020 VS 2024 VS 2031) & (US$ Million)
  • Table 24. Global Plasminogen Sales Value by Region (2020-2025) & (US$ Million)
  • Table 25. Global Plasminogen Sales Value by Region (2026-2031) & (US$ Million)
  • Table 26. Global Plasminogen Sales Value by Region (2020-2025) & (%)
  • Table 27. Global Plasminogen Sales Value by Region (2026-2031) & (%)
  • Table 28. Key Countries/Regions Plasminogen Sales Value Growth Trends, (US$ Million): 2020 VS 2024 VS 2031
  • Table 29. Key Countries/Regions Plasminogen Sales Value, (2020-2025) & (US$ Million)
  • Table 30. Key Countries/Regions Plasminogen Sales Value, (2026-2031) & (US$ Million)
  • Table 31. Kedrion(Prometic) Basic Information List
  • Table 32. Kedrion(Prometic) Description and Business Overview
  • Table 33. Kedrion(Prometic) Plasminogen Products, Services and Solutions
  • Table 34. Revenue (US$ Million) in Plasminogen Business of Kedrion(Prometic) (2020-2025)
  • Table 35. Kedrion(Prometic) Recent Developments
  • Table 36. Key Raw Materials Lists
  • Table 37. Raw Materials Key Suppliers Lists
  • Table 38. Plasminogen Downstream Customers
  • Table 39. Plasminogen Distributors List
  • Table 40. Research Programs/Design for This Report
  • Table 41. Key Data Information from Secondary Sources
  • Table 42. Key Data Information from Primary Sources

List of Figures

  • Figure 1. Plasminogen Product Picture
  • Figure 2. Global Plasminogen Sales Value, 2020 VS 2024 VS 2031 (US$ Million)
  • Figure 3. Global Plasminogen Sales Value (2020-2031) & (US$ Million)
  • Figure 4. Plasminogen Report Years Considered
  • Figure 5. Global Plasminogen Players Revenue Ranking (2024) & (US$ Million)
  • Figure 6. The 5 and 10 Largest Companies in the World: Market Share by Plasminogen Revenue in 2024
  • Figure 7. Plasminogen Market Share by Company Type (Tier 1, Tier 2, and Tier 3): 2020 VS 2024
  • Figure 8. Intravenous Injection Picture
  • Figure 9. Eye Drops Picture
  • Figure 10. Global Plasminogen Sales Value by Type (2020 VS 2024 VS 2031) & (US$ Million)
  • Figure 11. Global Plasminogen Sales Value Market Share by Type, 2024 & 2031
  • Figure 12. Product Picture of Ligneous Conjunctivitis
  • Figure 13. Product Picture of Diabetic Foot
  • Figure 14. Product Picture of Wound Healing
  • Figure 15. Product Picture of Others
  • Figure 16. Global Plasminogen Sales Value by Application (2020 VS 2024 VS 2031) & (US$ Million)
  • Figure 17. Global Plasminogen Sales Value Market Share by Application, 2024 & 2031
  • Figure 18. North America Plasminogen Sales Value (2020-2031) & (US$ Million)
  • Figure 19. North America Plasminogen Sales Value by Country (%), 2024 VS 2031
  • Figure 20. Europe Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 21. Europe Plasminogen Sales Value by Country (%), 2024 VS 2031
  • Figure 22. Asia Pacific Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 23. Asia Pacific Plasminogen Sales Value by Region (%), 2024 VS 2031
  • Figure 24. South America Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 25. South America Plasminogen Sales Value by Country (%), 2024 VS 2031
  • Figure 26. Middle East & Africa Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 27. Middle East & Africa Plasminogen Sales Value by Country (%), 2024 VS 2031
  • Figure 28. Key Countries/Regions Plasminogen Sales Value (%), (2020-2031)
  • Figure 29. United States Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 30. United States Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 31. United States Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 32. Europe Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 33. Europe Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 34. Europe Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 35. China Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 36. China Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 37. China Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 38. Japan Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 39. Japan Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 40. Japan Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 41. South Korea Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 42. South Korea Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 43. South Korea Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 44. Southeast Asia Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 45. Southeast Asia Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 46. Southeast Asia Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 47. India Plasminogen Sales Value, (2020-2031) & (US$ Million)
  • Figure 48. India Plasminogen Sales Value by Type (%), 2024 VS 2031
  • Figure 49. India Plasminogen Sales Value by Application (%), 2024 VS 2031
  • Figure 50. Plasminogen Industrial Chain
  • Figure 51. Plasminogen Manufacturing Cost Structure
  • Figure 52. Channels of Distribution (Direct Sales, and Distribution)
  • Figure 53. Bottom-up and Top-down Approaches for This Report
  • Figure 54. Data Triangulation
  • Figure 55. Key Executives Interviewed
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