BIOREACTORS AND FERMENTERS MARKET: OVERVIEW
As per Roots Analysis, the global bioreactors and fermenters market is estimated to grow from USD 23.2 billion in the current year to USD 73.9 billion by 2035, at a CAGR of 11.1% during the forecast period, till 2035.
The market sizing and opportunity analysis has been segmented across the following parameters:
Type of Product
Fabrication Material
- Glass
- Stainless Steel
- Single Use
Type of Bioprocess
- Batch and Fed-batch
- Continuous
Type of Biologic
- Antibodies
- Vaccines
- Cell Therapies
- Other Biologics
Key Geographical Regions
- North America
- Europe
- Asia-Pacific
- Middle East and North Africa
- Latin America
BIOREACTORS AND FERMENTERS MARKET: GROWTH AND TRENDS
Bioreactors and fermenters play an indispensable role in upstream biomanufacturing by providing the requisite conditions for producing high-value products, including recombinant proteins, tissue- engineered constructs and in vitro cell-based models. The technique of culturing cells via bioreactors was developed in the early twentieth century. The usage and scalability of such instruments evolved with the ever-increasing demand for novel biological products. In fact, biopharma companies, CMOs, and non-industry players have significantly invested in bioreactors to meet the rising demand for various therapies, including vaccines, fusion proteins, antibodies, hormones, interleukins, interferons, enzymes, and advanced therapeutic medicinal products (ATMPs).

In contrast to bioreactors, fermenters are used for the anaerobic cultivation of microbial (fungal or bacterial) cell populations to produce biologics that do not require significant post-translational modifications. The overall growth of the biopharmaceutical market, specifically post the COVID-19 pandemic, has led to a rise in demand for advanced upstream bioprocessing technologies, including bioreactors, offering lucrative opportunities to equipment manufacturers.
BIOREACTORS AND FERMENTERS MARKET: KEY INSIGHTS
The report delves into the current state of the bioreactors and fermenters market and identifies potential growth opportunities within the industry. Some key findings from the report include:
- Presently, over 255 companies have the required expertise to manufacture various types of bioreactors and fermenters across the globe.
- The current market landscape features the presence of both established and emerging players engaged in the manufacturing of bioreactors and fermenters of variable capacity ranges and modes of operation.
- Close to 80% of firms manufacture bioreactors and fermenters for batch processes; of these, 55% of the manufacturers have the capability to scale up their equipment from lab to commercial scale.

- The bioreactors and fermenters market landscape is fragmented; most of the well-established players are located in developed regions, while majority of small players are located in the Asia-Pacific region.
- Owing to the rise in demand for complex biologics, the requirement of novel bioreactors and fermenters is increasing, which has prompted the bioreactor and fermenter manufacturers to upgrade their capabilities.
- The global installed bioreactors and fermenters capacity is distributed across various geographies; over 60% of this capacity is installed in the in-house facilities of biologics manufacturers.
- Stainless steel bioreactors hold a prominent share of the current installed biomanufacturing capacity; the majority of this share is dedicated to the manufacturing of mammalian and microbial-based therapeutics.
- The global bioreactors and fermenters market is likely to grow at a CAGR of 11.1%, till 2035; the projected opportunity is likely to be driven by continuous manufacturing bioprocesses.
- In the long term, the disposable / single-use systems used for the manufacturing of antibodies and other novel biologics will likely emerge as the key growth drivers of the overall market.

BIOREACTORS AND FERMENTERS MARKET: KEY SEGMENTS
Bioreactors Segment Occupy the Largest Share of the Bioreactors and Fermenters Market
Based on the type of product, the market is segmented into bioreactors and fermenters. At present, the bioreactors segment holds the maximum share of the global bioreactors and fermenters market. Additionally, the fermenters segment is likely to grow at a faster pace during the forecasted period.
By Fabrication Material, Single Use Bioreactors is the Fastest Growing Segment of the Global Bioreactors and Fermenters Market
Based on the fabrication material, the market is segmented into glass, stainless steel and single use bioreactors. Currently, the stainless-steel bioreactors segment captures the highest proportion of the global bioreactors and fermenters market. Further, the bioreactors and fermenters market for single use bioreactors is likely to grow at a relatively higher CAGR owing to its several benefits, such as ~50% reduction in total energy and water consumption and ~40% cost saving by elimination of cleaning and sterilization processes after every batch production.
Batch and Fed-Batch Segment Occupy the Largest Share of the Bioreactors and Fermenters Market by Type of Bioprocess
Based on the type of bioprocess, the market is segmented into batch and fed batch, and continuous. At present, bioreactors used in batch and fed-batch mode hold the maximum share of the bioreactors and fermenters market. Further, it is worth highlighting that the bioreactors and fermenters market for the continuous type of bioprocess segment is likely to grow at a relatively higher CAGR.
Currently, the Antibodies Segment Holds the Largest Share of the Bioreactors and Fermenters Market
Based on the type of biologic, the global market is segmented into antibodies, vaccines, cell therapies and other biologics. Currently, the antibodies segment holds the largest market share. However, the bioreactors and fermenters market for vaccines segment is expected to witness substantial growth in the coming years.
Europe Accounts for the Largest Share of the Market
Based on key geographical regions, the market is segmented into North America, Europe, Asia-Pacific, Middle East and North Africa, and Latin America. Currently, Europe dominates the global bioreactors and fermenters market and accounts for the largest revenue share. Further, the market in Europe is expected to grow at a higher CAGR in the coming years.
Example Players in the Bioreactors and Fermenters Market
- Applikon Biotechnology
- Bionet
- Cytiva
- Eppendorf
- Merck
- Ollital Technology
- Parr Instrument Company
- Sartorius
- Shanghai Bailun Biological Technology
- Solaris Biotech
- Solida Biotech
- Zhengzhou Laboao Instrument Equipment (LABAO)
BIOREACTORS AND FERMENTERS MARKET: RESEARCH COVERAGE
- Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the global bioreactors and fermenters market, focusing on key market segments, including [A] type of product, [B] fabrication material, [C] type of bioprocess, [D] type of biologic and [E] key geographical regions.
- Market Landscape: A comprehensive evaluation of the companies engaged in manufacturing of bioreactors and fermenters, based on several relevant parameters, such as [A] year of establishment, [B] company size, [C] region of headquarters, [D] geographical reach, [E] capacity, [F] scale of operation, [G] scalability, [H] type of bioprocess, [I] type of cell culture, [J] mode of operation and [K] type of end user.
- Company Competitiveness Analysis: A comprehensive competitive analysis of bioreactors and fermenter manufacturers, examining factors, such as [A] manufacturer strength and [B] portfolio strength.
- Company Profiles: In-depth profiles of key manufacturers engaged in the bioreactors and fermenter market, focusing on [A] overview of the company, [B] financial information (if available), [C] product portfolio, and [D] recent developments and [E] an informed future outlook.
- Capacity Analysis: An insightful analysis of the global installed bioreactors and fermenters capacity of biologics, based on several relevant parameters, such as [A] fabrication material, [B] target disease indication, [C] source of cell culture, [D] reactor volume, [E] type of manufacturer and [F] key geographical regions.
- Case Study: A detailed discussion on the market landscape of bioprocess controllers and automation systems, based on several parameters, such as [A] scale of operation, [B] key features, [C] compatibility with bioreactor system, [D] type of bioprocess and [E] type of process controlled. Additionally, a comprehensive evaluation of companies involved in the development of bioprocess control software, and upstream and downstream controllers, based on several relevant parameters, such as [A] year of establishment, [B] company size, and [C] location of headquarters.
KEY QUESTIONS ANSWERED IN THIS REPORT
- How many companies are currently engaged in this market?
- Which are the leading companies in this market?
- What factors are likely to influence the evolution of this market?
- What is the current and future market size?
- What is the CAGR of this market?
- How is the current and future market opportunity likely to be distributed across key market segments?
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