PUBLISHER: The Business Research Company | PRODUCT CODE: 1713570
PUBLISHER: The Business Research Company | PRODUCT CODE: 1713570
Cytokine release syndrome (CRS) treatment involves medical interventions aimed at managing and alleviating the severe inflammatory response caused by cytokine release, which can occur with certain therapies such as CAR-T cell treatments. These treatments work to control symptoms, decrease inflammation, and enhance patient outcomes during intense cytokine reactions.
The primary drug types for managing cytokine release syndrome include corticosteroids, monoclonal antibodies, and other immunosuppressants. Corticosteroids are designed to reduce inflammation by mimicking hormones produced by the adrenal glands that regulate inflammation and the immune system. These drugs can be administered intravenously, subcutaneously, or orally, and are used in the treatment of oncological conditions, autoimmune disorders, and other applications. End users of these treatments include hospitals, specialty clinics, and home care settings.
The cytokine release syndrome treatment market research report is one of a series of new reports from the business research company that provides cytokine release syndrome treatment market statistics, including cytokine release syndrome treatment industry global market size, regional shares, competitors with an cytokine release syndrome treatment market share, detailed cytokine release syndrome treatment market segments, market trends and opportunities, and any further data you may need to thrive in the cytokine release syndrome treatment industry. This cytokine release syndrome treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The cytokine release syndrome treatment market size has grown rapidly in recent years. It will grow from $1.25 billion in 2024 to $1.42 billion in 2025 at a compound annual growth rate (CAGR) of 13.7%. The growth in the historic period can be attributed to increasing prevalence of cancer, rising adoption of immunotherapy, growth in biopharmaceutical investments, increasing clinical trials, growth in personalized medicine.
The cytokine release syndrome treatment market size is expected to see rapid growth in the next few years. It will grow to $2.35 billion in 2029 at a compound annual growth rate (CAGR) of 13.4%. The growth in the forecast period can be attributed to increasing prevalence of autoimmune disorders, increasing incidence of cancer therapies, increasing availability of targeted therapies, rising investment in biotechnology and life sciences, rising use of monoclonal antibodies. Major trends in the forecast period include implementation of biomarker based therapies, development of next generation IL-6 inhibitors, advancements in CAR-T cell therapy, adoption of biosimilars, advancements in monoclonal antibody therapies.
The growing incidence of cancer treatments is projected to drive the expansion of the cytokine release syndrome (CRS) treatment market. This increase in cancer treatments is fueled by the rising global cancer rates and advancements in diagnostic technologies that allow for earlier detection and a wider range of treatment options. Additionally, better survival rates and greater access to healthcare are contributing to the increased demand for these therapies. Managing CRS involves supportive care, anti-cytokine treatments, and continuous monitoring to address symptoms and reduce the inflammatory response triggered by cancer treatments. For example, the National Health Service (NHS) reported in January 2023 that over 320,000 people received cancer treatment between November 2021 and October 2022, the highest number recorded and an increase of more than 8,000 from previous figures. As a result, the rise in cancer treatments is fueling the growth of the CRS treatment market.
Leading companies in the CRS treatment market are advancing drug delivery technologies, such as intravenous infusion, to enhance treatment precision, minimize side effects, and improve patient outcomes. Intravenous infusion allows for the rapid and accurate delivery of drugs into the bloodstream, ensuring immediate therapeutic effects. For instance, in September 2023, Chugai Pharmaceutical Co. Ltd., a Japanese pharmaceutical company, received approval from Japan's Ministry of Health, Labor, and Welfare for Actemra (tocilizumab), a humanized anti-IL-6 receptor monoclonal antibody, for the treatment of CRS induced by various cancer therapies. Actemra Intravenous Infusion, available in 80 mg, 200 mg, and 400 mg doses, has been approved for treating CRS caused by cancer therapies beyond tumor-specific T-cell infusion therapy.
In March 2024, Merck & Co. Inc., a US-based pharmaceutical firm, acquired Harpoon Therapeutics for $680 million. This acquisition aims to expand Merck's cancer therapy portfolio, with a particular focus on T-cell engagers. This includes Harpoon's leading candidate, MK-6070 (formerly HPN328), which targets delta-like ligand 3 (DLL3), a protein linked to small cell lung cancer (SCLC) and neuroendocrine tumors. Harpoon Therapeutics, a US-based clinical-stage immunotherapy company, specializes in TriTAC-XR, a treatment designed for CRS.
Major companies operating in the cytokine release syndrome treatment market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche AG, Merck & Co. Inc., AbbVie Inc., Bayer AG, Sanofi S.A., Thermo Fisher Scientific Inc., Novartis AG, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Regeneron Pharmaceuticals Inc., Chugai Pharmaceutical Co. Ltd., Incyte Corporation, Swedish Orphan Biovitrum AB (publ), Bio-Techne Corporation, GenScript Biotech Corporation, Abcam plc, Applied Biological Materials Inc., Poolbeg Pharma, arigo Biolaboratories Corp., CytoAgents Inc, bluebird bio Inc.
North America was the largest region in the cytokine release syndrome treatment market in 2024. The regions covered in the cytokine release syndrome treatment market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the cytokine release syndrome treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The cytokine release syndrome treatment market consists of revenues earned by entities by providing services such as diagnostic services, clinical trials, hospital and medical services for treatment administration, and regulatory and compliance services. The market value includes the value of related goods sold by the service provider or included within the service offering. The cytokine release syndrome treatment also includes sales of supportive medications such as analgesics and antipyretics, anti-cytokine therapies, and diagnostic tools. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Cytokine Release Syndrome Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on cytokine release syndrome treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for cytokine release syndrome treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The cytokine release syndrome treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.