PUBLISHER: The Business Research Company | PRODUCT CODE: 1760470
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760470
Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening condition marked by abnormal blood clotting, which leads to damage in small blood vessels and results in hemolytic anemia, low platelet count, and kidney injury. It is often caused by genetic mutations or dysregulation in the complement system, leading to uncontrolled inflammation and vascular damage.
The main treatment options for atypical hemolytic uremic syndrome include complement inhibitors, plasma exchange therapy, supportive care, and antibiotics. Complement inhibitors are therapeutic agents that block or modulate the activation of the complement system, a critical component of the immune system involved in inflammation, immune response, and cell lysis. These inhibitors are administered through various routes, such as intravenous, subcutaneous, and oral. Technologies involved in the treatment include genetic testing and diagnostic tools, real-time monitoring and complement activation technologies, treatment delivery systems, and digital health solutions. These are used in various healthcare settings, including specialty clinics, home care environments, and ambulatory care centers.
The atypical hemolytic uremic syndrome treatment market research report is one of a series of new reports from The Business Research Company that provides atypical hemolytic uremic syndrome treatment market statistics, including atypical hemolytic uremic syndrome treatment industry global market size, regional shares, competitors with atypical hemolytic uremic syndrome treatment market share, detailed atypical hemolytic uremic syndrome treatment market segments, market trends and opportunities, and any further data you may need to thrive in the atypical hemolytic uremic syndrome treatment industry. This atypical hemolytic uremic syndrome treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The atypical hemolytic uremic syndrome treatment market size has grown strongly in recent years. It will grow from $1.63 billion in 2024 to $1.75 billion in 2025 at a compound annual growth rate (CAGR) of 7.7%. The growth during the historic period can be attributed to several factors, including an increase in clinical trials, growing awareness of the disease, government support for research, enhanced diagnostic capabilities, and a rising incidence of the disease.
The atypical hemolytic uremic syndrome treatment market size is expected to see strong growth in the next few years. It will grow to $2.34 billion in 2029 at a compound annual growth rate (CAGR) of 7.5%. The growth during the forecast period can be attributed to factors such as government support initiatives, a focus on complement dysregulation, growing patient awareness, increased availability of treatments, and improved diagnostic techniques. Key trends in the forecast period include next-generation complement inhibitors, digital health monitoring and AI tools, AI-driven drug discovery, personalized medicine, and genotyping and biomarker-based diagnostics.
The increasing demand for targeted therapies is expected to drive the growth of the atypical hemolytic uremic syndrome (aHUS) treatment market. Targeted therapies are medical treatments that specifically focus on and disrupt the molecular pathways involved in disease progression. The growing demand for these therapies stems from their ability to deliver more precise treatments with fewer side effects, leading to improved patient outcomes and offering alternatives to traditional, broader treatments. In the case of atypical hemolytic uremic syndrome, targeted therapies work by blocking the overactivation of the complement system, which is the primary cause of the disease. This allows for precise interventions that reduce damage to blood vessels and kidneys. For example, in October 2023, NHS England reported that 11 million hormone replacement therapy (HRT) items were prescribed in England, a 47% increase from 2021-22, with approximately 2.3 million patients receiving prescriptions, marking a 29% year-on-year rise. Consequently, the increasing demand for targeted therapies is fueling the growth of the atypical hemolytic uremic syndrome treatment market.
Key players in the atypical hemolytic uremic syndrome treatment market are focusing on developing cutting-edge therapies, such as monoclonal antibody drugs, to enhance targeted complement inhibition and improve patient outcomes. Monoclonal antibodies are laboratory-engineered proteins that mimic the immune system's ability to combat harmful pathogens by specifically targeting and binding to certain proteins involved in disease mechanisms. For example, in January 2025, AstraZeneca Pharma India Limited, a biopharmaceutical company based in India, received approval from the Central Drugs Standard Control Organization (CDSCO) to import, sell, and distribute eculizumab (marketed as Soliris) in India. These monoclonal antibodies specifically bind to the complement protein C5, preventing its cleavage and thereby blocking the formation of the terminal complement complex responsible for immune-mediated cell damage. Eculizumab is used to treat rare and severe conditions such as paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), generalized myasthenia gravis, and neuromyelitis optica spectrum disorder by preventing complement-mediated damage.
In October 2022, Amgen Inc., a US-based biotechnology company, acquired ChemoCentryx Inc. for approximately $3.7 billion. This acquisition is part of Amgen's strategy to expand its portfolio in the field of autoimmune and rare diseases by incorporating ChemoCentryx's innovative therapies and expertise in complement-based treatments. ChemoCentryx Inc., a US-based biopharmaceutical company, specializes in developing treatments for rare conditions, including atypical hemolytic uremic syndrome (aHUS).
Major players in the atypical hemolytic uremic syndrome treatment market are F. Hoffmann-La Roche Ltd., Bristol-Myers Squibb Company, AstraZeneca plc, Novartis AG, Amgen Inc., Teva Pharmaceutical Industries Ltd., Chugai Pharmaceutical Co. Ltd., Alnylam Pharmaceuticals Inc., Vifor Pharma Ltd., Samsung Bioepis Co. Ltd., Fuji Pharma Co. Ltd., Aevitas Therapeutics Inc., Pharmasyntez JSC, Omeros Corporation, ChemoCentryx Inc., ISU Abxis Co. Ltd., Greenovation Biotech GmbH, Akari Therapeutics plc, NovelMed Therapeutics Inc., Eleva GmbH.
North America was the largest region in the atypical hemolytic uremic syndrome treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in atypical hemolytic uremic syndrome report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the atypical hemolytic uremic syndrome market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The atypical hemolytic uremic syndrome (aHUS) market consists of revenues earned by entities by providing services such as renal support and dialysis, genetic testing and counseling, long-term monitoring and follow-up. The market value includes the value of related goods sold by the service provider or included within the service offering. The atypical hemolytic uremic syndrome (aHUS) market also includes sales of immunosuppressive therapies, plasma exchange equipment, dialysis machines, and supportive care medications. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Atypical Hemolytic Uremic Syndrome Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on atypical hemolytic uremic syndrome treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for atypical hemolytic uremic syndrome treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The atypical hemolytic uremic syndrome treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.