PUBLISHER: The Business Research Company | PRODUCT CODE: 1815524
PUBLISHER: The Business Research Company | PRODUCT CODE: 1815524
Polyclonal antibodies, stemming from multiple B-cell clones, offer a diverse range of antibody molecules, a favored choice among life science and translational medicine researchers. Their ease of handling during immunization and bleeding processes renders them highly sought after in research settings.
The primary and secondary antibodies constitute the main products derived from polyclonal antibodies. A primary antibody within this polyclonal mixture binds specifically to the target antigen, playing a pivotal role in various applications. These applications span immunohistochemistry, Western blotting, ELISA, and an array of immunological assays. The sources of polyclonal antibodies typically include rabbits, goats, sheep, and other animals, serving purposes in research, diagnostics, and therapeutic endeavors across academic institutions, research centers, pharmaceutical and biotech firms, diagnostic facilities, and hospitals.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sudden escalation of U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the pharmaceutical sector. Companies are grappling with higher costs on imported active pharmaceutical ingredients (APIs), glass vials, and laboratory equipment-many of which have limited alternative sources. Generic drug manufacturers, already operating with minimal profit margins, are particularly affected, with some scaling back production of low-margin medications. Biotech firms are also experiencing delays in clinical trials due to shortages of specialized reagents linked to tariffs. In response, the industry is shifting API production to regions like India and Europe, building up inventory reserves, and advocating for tariff exemptions on essential medicines.
The polyclonal antibodies market research report is one of a series of new reports from The Business Research Company that provides polyclonal antibodies market statistics, including polyclonal antibodies industry global market size, regional shares, competitors with a polyclonal antibodies market share, detailed polyclonal antibodies market segments, market trends, and opportunities, and any further data you may need to thrive in the polyclonal antibodies industry. This polyclonal antibodies market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The polyclonal antibodies market size has grown steadily in recent years. It will grow from $1.41 billion in 2024 to $1.48 billion in 2025 at a compound annual growth rate (CAGR) of 5.0%. The growth in the historic period can be attributed to biomedical research demand, increased diagnostic applications, an increase in chronic diseases, and a wide range of applications
The polyclonal antibodies market size is expected to see strong growth in the next few years. It will grow to $1.94 billion in 2029 at a compound annual growth rate (CAGR) of 6.9%. The growth in the forecast period can be attributed to expanding diagnostic technologies, therapeutic advancements, a rise in infectious diseases, increased research funding, collaborations and partnerships. Major trends in the forecast period include advancements in antibody engineering, a growing role in cancer immunotherapy, a rise of biosimilar polyclonal antibodies, application in neurological disorders, regulatory advances and compliance.
The forecast of 6.9% growth over the next five years reflects a modest reduction of 0.2% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper U.S. research laboratories by increasing the cost of rabbit-derived immunoglobulins and neutralizing antibody mixtures sourced from China and Denmark, thereby prolonging biomedical research timelines and elevating preclinical study costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The anticipated rise in cancer cases is poised to drive the expansion of the polyclonal antibodies market. These antibodies play a pivotal role in cancer research and treatment, aiding in biomarker detection, targeted therapy, and immunotherapy. Notably, the escalating instances of stomach cancer in Australia in 2022, projected by Cancer Australia, underscore the market's growth potential. The surge in cancer diagnoses significantly contributes to the demand for polyclonal antibodies, enhancing cancer diagnosis and treatment methodologies.
The surge in infectious disease outbreaks is anticipated to fuel the growth of the polyclonal antibodies market. These antibodies are crucial in understanding and managing infectious diseases due to their versatility and specificity. Highlighting this trend, the Centers for Disease Control and Prevention's report in March 2023 outlined an increase in tuberculosis cases in the United States. This escalation in infectious diseases emphasizes the essential role of polyclonal antibodies in combating such health crises.
Research and development emerge as a prominent trend driving the polyclonal antibodies market. Leading companies are actively engaged in R&D endeavors to enhance their efficacy and maintain market leadership. For instance, GigaGen Inc.'s July 2022 publication showcases their pioneering work on GIGA-2050, a recombinant polyclonal product targeting SARS-CoV-2. This innovative product, derived from a single master cell bank containing over 12,000 antibodies, signifies a significant leap in manufacturing recombinant polyclonal antibodies, surpassing prior industry standards.
Strategic partnerships form a cornerstone strategy for major players in the polyclonal antibodies market. Companies leverage collaborative alliances to optimize resources and capabilities for mutual benefit. An exemplar is the partnership announced in October 2022 between SAB Biotherapeutics and Emergent BioSolutions, Inc. This collaboration entails Emergent providing manufacturing services to SAB for clinical investigational medications and potential commercial manufacturing. Additionally, the agreement allows Emergent access to SAB's advanced DiversitAb technology for future product development, leveraging fully human polyclonal antibodies using transchromosomic cows.
In February 2022, Rockland Immunochemical Inc., a US-based company known for its development of antibody-based assays and research tools, completed the acquisition of Antibodies-Online GmbH. This undisclosed investment allows Rockland to integrate expertise in antibody design, development, and manufacturing. The acquisition notably capitalizes on Antibodies-Online GmbH's esteemed e-commerce brand, extensive supplier network, and proprietary antibody-online technology stack. Notably, Antibodies-Online GmbH, based in Germany, is recognized for its provision of high-quality, specifically-targeted polyclonal primary antibodies.
Major companies operating in the polyclonal antibodies market include Abcam plc, GenScript Biotech Corporation, Merck KGaA, Thermo Fisher Scientific Inc., Becton Dickinson and Company, BioLegend Inc., Bio-Rad Laboratories Inc., Cell Signaling Technology Inc., F. Hoffmann-La Roche Ltd., PerkinElmer Inc., Creative Diagnostics, Agilent Technologies, Analytik Jena GmbH, Atlas Antibodies, Danaher Corporation, DC Biosciences Ltd., Illumia Inc., ImmonoPresice Antibodies Ltd, Fujirebio, Omega BioTek Inc., Dovetail Genomics LLC, Abnova Corporation, Santa Cruz Biotechnology Inc., Enzo Life Sciences Inc., Rockland Immunochemicals Inc., IGY Life Sciences, Genway Biotech, Good Biotech, Gallus Immunotech Inc., BioGenes GmbH, Capralogics Inc., Bio X Cell
North America was the largest region in the polyclonal antibodies market in 2024. Asia-Pacific is expected to be the fastest-growing region in the global polyclonal antibodies market size forecast period. The regions covered in the polyclonal antibodies market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
The countries covered in the polyclonal antibodies market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain
The polyclonal antibodies market consists of sales of anti-cd4 polyclonal antibodies, anti-her2 polyclonal antibodies, and anti-insulin polyclonal antibodies. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Polyclonal Antibodies Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on polyclonal antibodies market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for polyclonal antibodies ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The polyclonal antibodies market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.