Percutaneous Nephrolithotomy Global Market Report 2025

Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure used to remove kidney stones (renal calculi) from the urinary tract. This procedure involves making a small incision in the skin and creating a direct channel to the kidney through which instruments are inserted to break up and extract the stones. PCNL is employed when other less invasive methods, such as shock wave lithotripsy or ureteroscopy, are ineffective or unsuitable.

The main types of kidney stones treated by percutaneous nephrolithotomy include magnesium ammonium phosphate stones, calcareous stones, and uric acid calculi. Magnesium ammonium phosphate (MAP) stones are composed of magnesium, ammonium, and phosphate ions. The components involved in PCNL include accessories, devices, and services, which are utilized by end users such as ambulatory surgical centers, clinics, and hospitals.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The percutaneous nephrolithotomy market research report is one of a series of new reports from The Business Research Company that provides percutaneous nephrolithotomy market statistics, including the percutaneous nephrolithotomy industry global market size, regional shares, competitors with percutaneous nephrolithotomy market share, detailed percutaneous nephrolithotomy market segments, market trends, and opportunities, and any further data you may need to thrive in the percutaneous nephrolithotomy industry. These percutaneous nephrolithotomy market research reports deliver a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The percutaneous nephrolithotomy market size has grown strongly in recent years. It will grow from $17.9 billion in 2024 to $19.39 billion in 2025 at a compound annual growth rate (CAGR) of 8.3%. The growth in the historic period can be attributed to increasing prevalence of kidney stones, rising demand for effective and efficient treatment options for kidney stones, expansion of healthcare infrastructure in emerging economies, aging population leading to a higher incidence of kidney stones, surge in research and development activities, increasing healthcare expenditure, growing emphasis on patient-centric healthcare.

The percutaneous nephrolithotomy market size is expected to see strong growth in the next few years. It will grow to $26.6 billion in 2029 at a compound annual growth rate (CAGR) of 8.2%. The growth in the forecast period can be attributed to growing adoption of minimally invasive surgical procedures, rising demand for effective stone removal techniques, increasing awareness about the benefits of percutaneous nephrolithotomy, growing geriatric population prone to kidney stone formation, growing availability of advanced medical technologies for stone removal, increasing focus on patient-centric care, increasing preference for outpatient procedures. Major trends in the forecast period include adoption of miniaturized instruments, advancement in imaging technologies, implementation of robotics, adoption of disposable devices, advancement in stone retrieval devices, advancement in anesthesia techniques, implementation of enhanced infection control measures, implementation of multimodal pain management, development of training programs.

The forecast of 8.2% growth over the next five years reflects a modest reduction of 0.6% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may pose challenges for U.S. urology centers by increasing costs for nephroscopes and lithotripsy devices imported from Japan and Germany, potentially delaying kidney stone removal procedures and raising surgical department costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing prevalence of renal diseases is set to drive the growth of the percutaneous nephrolithotomy market in the coming years. Renal diseases encompass a variety of conditions affecting the kidneys and hindering their proper functioning. Factors contributing to the prevalence of renal diseases include rising rates of diabetes and hypertension, an aging population, lifestyle choices, genetic factors, chronic conditions, and improved awareness and diagnosis. Percutaneous nephrolithotomy plays a crucial role in managing renal diseases by offering a minimally invasive surgical procedure to remove large or complex kidney stones, alleviate pain, prevent urinary tract infections, and enhance kidney function. For example, a UK-based Kidney Research Commission reported in June 2023 that kidney disease affected 7.19 million people in the UK in 2023 and is projected to increase to 7.61 million by 2033. Hence, the increasing prevalence of renal diseases is fueling growth in the percutaneous nephrolithotomy market.

Leading companies in the percutaneous nephrolithotomy market are concentrating on implementing innovative solutions, such as robot-assisted surgical platforms, to improve surgical precision and patient outcomes. A robot-assisted surgical platform is an advanced medical system utilizing robotic technology to aid surgeons in performing complex procedures with enhanced precision, control, and flexibility. For instance, Ethicon Inc., a US-based Johnson & Johnson MedTech company, announced in February 2023 the successful robotic-assisted removal of kidney stones in the first patient using the MONARCH Platform for urology. This platform enables urologists to navigate the kidney with robotic assistance, facilitating access, clearance, and control via a handheld controller. It offers a unified platform supporting ureteroscopic and percutaneous nephrolithotomy (PCNL) procedures, delivering enhanced navigation, access, clearance, and control compared to traditional methods.

The growing adoption of minimally invasive surgeries (MIS) is expected to drive the expansion of the percutaneous nephrolithotomy (PCNL) market. Invasive surgeries involve making incisions to enter the body for the treatment or diagnosis of medical conditions. The increasing preference for MIS is attributed to key benefits such as shorter recovery times, reduced hospital stays, lower risk of complications, less pain and scarring, and greater precision due to advanced technologies. These advantages make MIS particularly beneficial for percutaneous nephrolithotomy (PCNL), as it offers a less invasive method for treating kidney stones. For example, in January 2023, reports from Intuitive Surgical Inc., a US-based manufacturer of robotic products, revealed that in 2022, approximately 1,875,000 surgical procedures were performed using Vinci Surgical Systems. This represented an 18% increase compared to the 1,594,000 procedures conducted in 2021. As a result, the rising adoption of minimally invasive surgeries is fueling the growth of the percutaneous nephrolithotomy market.

Major companies operating in the percutaneous nephrolithotomy market are Boston Scientific Corporation, Zimmer Biomet Holdings Inc., Olympus Corporation, Terumo Corporation, Coloplast Corporation, B. Braun, Cook Medical, Teleflex Incorporated, Karl Storz Se And Co. KG, Merit Medical Systems, Richard Wolf GmbH, AngioDynamics, Argon Medical Devices, Dornier MedTech, EDAP TMS, Allengers Medical Systems Limited, DirexGroup, Envaste Limited, ELMED Lithotripsy Systems, PolyDiagnost, Attikouris Enterprises Ltd., Advin Urology, Avenda Health, Guangzhou Potent Optotronic Technology Co. Ltd., Surgimedik

North America was the largest region in the percutaneous nephrolithotomy market in 2024. The regions covered in the percutaneous nephrolithotomy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the percutaneous nephrolithotomy market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The percutaneous nephrolithotomy market consists of revenues earned by entities by providing services such as preoperative consultation and assessment, imaging services, anesthesia services, and postoperative care. The market value includes the value of related goods sold by the service provider or included within the service offering. The percutaneous nephrolithotomy market also includes sales of nephroscopes, lithotripters, and guidewires. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Percutaneous Nephrolithotomy Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on percutaneous nephrolithotomy market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

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Where is the largest and fastest growing market for percutaneous nephrolithotomy ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The percutaneous nephrolithotomy market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

• The market characteristics section of the report defines and explains the market.
• The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
• The forecasts are made after considering the major factors currently impacting the market. These include:

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

• Market segmentations break down the market into sub markets.
• The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
• The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
• The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.

Scope

• Markets Covered:1) By Type: Magnesium Ammonium Phosphate Stone Type; Calcareous Type; Uric Acid Calculi Type
• 2) By Component: Accessories; Devices; Services
• 3) By End-User: Ambulatory Surgical Centers; Clinics; Hospitals
• Subsegments:
• 1) By Magnesium Ammonium Phosphate Stone Type: Struvite Stones; Triple Phosphate Stones
• 2) By Calcareous Type: Calcium Oxalate Stones; Calcium Phosphate Stones
• 3) By Uric Acid Calculi Type: Primary Uric Acid Stones; Secondary Uric Acid Stones
• Companies Mentioned: Boston Scientific Corporation; Zimmer Biomet Holdings Inc.; Olympus Corporation; Terumo Corporation; Coloplast Corporation; B. Braun; Cook Medical; Teleflex Incorporated; Karl Storz Se And Co. KG; Merit Medical Systems; Richard Wolf GmbH; AngioDynamics; Argon Medical Devices; Dornier MedTech; EDAP TMS; Allengers Medical Systems Limited; DirexGroup; Envaste Limited; ELMED Lithotripsy Systems; PolyDiagnost; Attikouris Enterprises Ltd.; Advin Urology; Avenda Health; Guangzhou Potent Optotronic Technology Co. Ltd.; Surgimedik
• Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain.
• Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
• Time Series: Five years historic and ten years forecast.
• Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
• Data Segmentations: country and regional historic and forecast data, market share of competitors, market segments.
• Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
• Delivery Format: PDF, Word and Excel Data Dashboard.