PUBLISHER: The Business Research Company | PRODUCT CODE: 1826806
PUBLISHER: The Business Research Company | PRODUCT CODE: 1826806
Treatment for metabolic dysfunction-associated steatohepatitis (MASH) involves both medical and lifestyle approaches that target the inflammation and liver damage caused by fat buildup in the liver, which is linked to metabolic issues such as obesity, diabetes, and insulin resistance. The goal is to improve liver function and metabolic health outcomes.
The primary treatments for MASH include medications and therapies. Drug treatments involve the use of pharmaceutical agents to reduce liver inflammation, fibrosis, and fat accumulation, aiming to enhance liver function and halt disease progression. These treatments are provided to patients through various channels, including hospital pharmacies, online pharmacies, retail pharmacies, and specialty clinics, and can be used in settings such as hospitals, homecare, and others.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The metabolic dysfunction-associated steatohepatitis (MASH) treatment market research report is one of a series of new reports from The Business Research Company that provides metabolic dysfunction-associated steatohepatitis (MASH) treatment market statistics, including metabolic dysfunction-associated steatohepatitis (MASH) treatment industry global market size, regional shares, competitors with metabolic dysfunction-associated steatohepatitis (MASH) treatment market share, detailed metabolic dysfunction-associated steatohepatitis (MASH) treatment market segments, market trends and opportunities, and any further data you may need to thrive in the metabolic dysfunction-associated steatohepatitis (MASH) treatment industry. This metabolic dysfunction-associated steatohepatitis (MASH) treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The metabolic dysfunction-associated steatohepatitis (mash) treatment market size has grown exponentially in recent years. It will grow from $2 billion in 2024 to $2.59 billion in 2025 at a compound annual growth rate (CAGR) of 29.7%. The growth in the historic period can be attributed to the rising incidence of non-alcoholic steatohepatitis, modern dietary habits, eating high in processed foods, sedentary lifestyles, and increasing prevalence of metabolic.
The metabolic dysfunction-associated steatohepatitis (mash) treatment market size is expected to see exponential growth in the next few years. It will grow to $7.29 billion in 2029 at a compound annual growth rate (CAGR) of 29.5%. The growth in the forecast period can be attributed to the increasing prevalence of obesity and obesity-related diseases, early intervention, reimbursement mechanisms, insurance coverage, and growing awareness of liver diseases. Major trends in the forecast period include an increase in technological advancements, pipeline development, strategic collaborations and partnerships, personalized medicine and precision therapeutics, and investment in clinical trials and research.
The forecast of 29.5% growth over the next five years reflects a modest reduction of 0.3% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. by increasing the cost of fibroblast growth factor analogs and non-invasive liver diagnostic tools sourced from Switzerland and Japan, thereby delaying early intervention and elevating hepatology department expenditures. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The growing prevalence of obesity is expected to drive the expansion of the metabolic dysfunction-associated steatohepatitis (MASH) treatment market in the future. Obesity is a condition marked by excessive body fat accumulation, which can harm overall health and is usually defined by a body mass index (BMI) of 30 or higher. The global rise in obesity is primarily attributed to factors such as sedentary lifestyles, poor dietary habits, and metabolic risks. MASH treatment in obesity aims to combat insulin resistance, reduce liver fat, and enhance metabolic health through both lifestyle modifications and targeted treatments. For example, a report from the World Heart Foundation, a Switzerland-based global cardiovascular organization, published in March 2023, highlighted that around 2.3 billion adults and children worldwide are obese or overweight, and this figure is expected to increase to 2.7 billion by 2025, reflecting the ongoing obesity trend. Consequently, the rise in obesity rates is propelling the growth of the MASH treatment market.
Major companies in the metabolic dysfunction-associated steatohepatitis (MASH) treatment market are focusing on the development of innovative products, including solutions for liver fibrosis. These treatments aim to address the root causes of liver damage, with a focus on lifestyle changes, antiviral medications, and emerging antifibrotic therapies. The goal is to prevent the progression of fibrosis, potentially reversing it, and enhancing liver function. For example, in March 2024, Madrigal Pharmaceuticals, a US-based biopharmaceutical company, received FDA approval for Rezdiffra (resmetirom). This is the first-ever treatment for MASH with moderate to severe liver fibrosis. Rezdiffra, a daily oral tablet, showed effectiveness in resolving MASH without worsening fibrosis and improving liver fibrosis in phase 3 clinical trials. This breakthrough provides a non-invasive alternative to liver biopsies, significantly improving patient access and outcomes in managing fatty liver disease.
In January 2024, Suzhou Ribo Life Science Co., Ltd., a clinical-stage company based in China, and Ribocure Pharmaceuticals AB (Ribo), a clinical-stage biotechnology company from Sweden, announced a $2 billion collaboration with Boehringer Ingelheim. This partnership aims to develop innovative treatments for nonalcoholic steatohepatitis (NASH) and metabolic dysfunction-associated steatohepatitis (MASH). The collaboration will combine Ribo's RNAi therapeutic platform with Boehringer Ingelheim's expertise in cardiovascular, renal, and metabolic diseases. The goal is to address the critical need for effective therapies that can halt the progression of NASH and restore liver function. Boehringer Ingelheim, a pharmaceutical company based in Germany, is actively working on treatments for MASH.
Major players in the metabolic dysfunction-associated steatohepatitis (mash) treatment market are Pfizer Inc., Johnson & Johnson, Merck & Co. Inc., Sanofi SA, AstraZeneca PLC, Novartis AG, Eli Lily and Company, Gilead Sciences Inc., Boehringer Ingelheim International GmbH, Novo Nordisk A/S, Apollo Health and Lifestyle Limited, Jenny Craig, Celerion, Nutrisystem, Madrigal Pharmaceuticals, Anoos Clinic, 89 Bio, Biosynth, DiogenX, Galectin Therapeutics Inc., Galmed Pharmaceuticals, and Hepion Pharmaceuticals.
North America was the largest region in the metabolic dysfunction-associated steatohepatitis (MASH) treatment market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in metabolic dysfunction-associated steatohepatitis (MASH) treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the metabolic dysfunction-associated steatohepatitis (MASH) treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The metabolic dysfunction-associated steatohepatitis (MASH) treatment market consists of revenues earned by entities by providing services such as clinical care services, nutritional counseling, pharmacotherapy management, patient education, and support programs. The market value includes the value of related goods sold by the service provider or included within the service offering. The metabolic dysfunction-associated steatohepatitis (MASH) treatment market also includes sales of antioxidants, antidiabetic drugs, and liver protective supplements. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Metabolic Dysfunction-Associated Steatohepatitis (MASH) Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on metabolic dysfunction-associated steatohepatitis (mash) treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for metabolic dysfunction-associated steatohepatitis (mash) treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The metabolic dysfunction-associated steatohepatitis (mash) treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.