PUBLISHER: The Business Research Company | PRODUCT CODE: 1826931
PUBLISHER: The Business Research Company | PRODUCT CODE: 1826931
Granulomatosis with Polyangiitis (GPA) treatment includes medications aimed at controlling inflammation, suppressing the immune system, and preventing organ damage. GPA is a rare autoimmune disease that causes inflammation in small to medium-sized blood vessels, leading to restricted blood flow and tissue damage, particularly affecting the respiratory tract and kidneys. The primary treatment approach involves immunosuppressive therapies, including corticosteroids and biologics, to reduce inflammation and protect organ function.
The key drug categories for treating granulomatosis with polyangiitis include steroids, immunosuppressants, and others. Steroids are anti-inflammatory medications that help decrease swelling and suppress immune activity. In GPA management, they are commonly used alongside other drugs to control symptoms. The treatment approaches involve immunosuppressants and corticosteroids, administered through various routes such as oral and intravenous. These medications are distributed through hospital pharmacies, retail pharmacies, and online pharmacies and are utilized by different end users, including hospitals, home care, specialty clinics, and others.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The granulomatosis with polyangiitis treatment market research report is one of a series of new reports from The Business Research Company that provides granulomatosis with polyangiitis treatment market statistics, including the granulomatosis with polyangiitis treatment industry global market size, regional shares, competitors with the granulomatosis with polyangiitis treatment market share, detailed granulomatosis with polyangiitis treatment market segments, market trends, and opportunities, and any further data you may need to thrive in the granulomatosis with polyangiitis treatment industry. This granulomatosis with polyangiitis treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The granulomatosis with polyangiitis treatment market size has grown strongly in recent years. It will grow from $2.36 billion in 2024 to $2.55 billion in 2025 at a compound annual growth rate (CAGR) of 7.9%. The growth in the historic period can be attributed to the growing need for the drugs, the growing number of clinical trials, the rising demand for effective treatment, the growing emphasis on personalized medicine, and increasing diagnosis rates of the disorder.
The granulomatosis with polyangiitis treatment market size is expected to see strong growth in the next few years. It will grow to $3.44 billion in 2029 at a compound annual growth rate (CAGR) of 7.8%. The growth in the forecast period can be attributed to the increasing prevalence of autoimmune diseases, rising prevalence of granulomatosis, increase in the incidences of polyangiitis, and rise in the prevalence of immunological disorders. Major trends in the forecast period include advancements in drug development, developments in healthcare, advancements in diagnostic techniques, advancements in treatment options, and the development of biologics and biosimilars.
The forecast of 7.8% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. market by increasing the cost of rituximab biosimilars and Antineutrophil Cytoplasmic Antibodies test kits(ANCA) test kits sourced from India and Sweden, thereby delaying diagnosis of this rare vasculitis by 3 weeks and elevating rheumatology treatment costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The growing prevalence of autoimmune diseases is expected to drive the expansion of the granulomatosis with polyangiitis treatment market. Autoimmune diseases arise when the body's immune system mistakenly targets healthy cells and tissues, causing inflammation and damage across various organs. This increasing prevalence is linked to environmental triggers such as infections, chemicals, pollutants, and lifestyle changes. Granulomatosis with polyangiitis treatment plays a crucial role in managing autoimmune diseases by using immunosuppressive therapies such as corticosteroids and cyclophosphamide, which help control inflammation and prevent organ damage. Early intervention and personalized treatment are essential for managing other autoimmune conditions with similar mechanisms. For example, according to a report published in June 2023 by the Office for National Statistics, a UK-based government department, the global population affected by multiple sclerosis (MS), an autoimmune disease, increased from 2.8 million in 2022 to 2.9 million in 2023. As a result, the rising prevalence of autoimmune diseases is fueling the growth of the granulomatosis with polyangiitis treatment market.
Leading companies in the granulomatosis with polyangiitis treatment market are emphasizing the development of innovative products, such as oral corticosteroids, to provide more effective treatment options that improve disease management while reducing the long-term side effects of steroid use. Oral corticosteroids help alleviate inflammation and suppress the immune system and are widely used for allergies, autoimmune diseases, and inflammatory disorders. For instance, in October 2024, AstraZeneca plc, a UK-based pharmaceutical company, announced the approval of Fasenra (bevacizumab) in the European Union as an add-on treatment for adult patients with relapsing or refractory eosinophilic granulomatosis with polyangiitis (EGPA). This approval followed positive findings from the MANDARA Phase III trial, which demonstrated Fasenra's effectiveness in achieving remission and decreasing dependency on oral corticosteroids in EGPA patients.
In October 2022, Amgen Inc., a US-based biotechnology company, acquired ChemoCentryx Inc. for $3.7 billion. This acquisition aims to bolster Amgen's inflammation and nephrology portfolio by broadening the market reach of Tavneos (avacopan) and enhancing its presence in autoimmune and rare disease treatments. ChemoCentryx Inc. is a US-based company specializing in treatments for granulomatosis with polyangiitis and other inflammatory diseases.
Major players in the granulomatosis with polyangiitis treatment market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Merck & Co. Inc., Sanofi S.A., AstraZeneca plc, GlaxoSmithKline plc, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Teva Pharmaceutical Industries Ltd., Otsuka Pharmaceutical Co. Ltd., Regeneron Pharmaceuticals Inc., Astellas Pharma Inc., Vertex Pharmaceuticals Incorporated, Genentech Inc., Incyte Corporation, Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., ChemoCentryx Inc., Medac Pharma Inc., InflaRx GmbH.
North America was the largest region in the granulomatosis with polyangiitis treatment market in 2024. The regions covered in granulomatosis with polyangiitis treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the granulomatosis with polyangiitis treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The granulomatosis with polyangiitis treatment market includes sales of symptomatic treatment, monoclonal antibodies, and plasmapheresis. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Granulomatosis With Polyangiitis Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on granulomatosis with polyangiitis treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for granulomatosis with polyangiitis treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The granulomatosis with polyangiitis treatment market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.