PUBLISHER: The Business Research Company | PRODUCT CODE: 1827018
PUBLISHER: The Business Research Company | PRODUCT CODE: 1827018
Hand foot syndrome, also known as palmar-plantar erythrodysesthesia, is a condition triggered by chemotherapy or certain medications. It leads to redness, swelling, pain, and peeling on the palms of the hands and the soles of the feet. In more severe cases, blisters and ulcerations may develop, impacting daily activities.
The primary treatments for hand foot syndrome include both systemic and topical options. Systemic treatments involve medications that work throughout the body to relieve symptoms and prevent complications. These treatments are utilized in various fields such as oncology, dermatology, and others, and are typically administered in hospitals, clinics, and homecare settings.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.
The hand foot syndrome market research report is one of a series of new reports from The Business Research Company that provides hand foot syndrome market statistics, including the hand foot syndrome industry's global market size, regional shares, competitors with a hand foot syndrome market share, detailed hand foot syndrome market segments, market trends and opportunities, and any further data you may need to thrive in the hand foot syndrome industry. This hand foot syndrome market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The hand foot syndrome market size has grown strongly in recent years. It will grow from $0.48 billion in 2024 to $0.52 billion in 2025 at a compound annual growth rate (CAGR) of 7.3%. The growth in the historic period can be attributed to increasing prevalence of chronic diseases, growth in global cancer diagnoses, rising focus on patient-centered cancer care, increase in government initiatives and healthcare funding, and growing pharmaceutical focus on rare and orphan diseases.
The hand foot syndrome market size is expected to see strong growth in the next few years. It will grow to $0.66 billion in 2029 at a compound annual growth rate (CAGR) of 6.3%. The growth in the forecast period can be attributed to increasing focus on palliative and symptom management care, growth of the oncology biopharmaceuticals, increase in clinical trials for HFS treatments, rising demand for oral and at-home treatments, global rise in health insurance coverage. Major trends in the forecast period include integration of virtual reality (VR) for symptom management, advancements in wearable health devices, CRISPR technology for gene editing and personalized treatments, development of AI-powered predictive tools, and use of 3d imaging for better understanding of skin conditions.
The forecast of 6.3% growth over the next five years reflects a modest reduction of 0.6% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may pose a significant challenge for the U.S. by restricting access to specialized topical emollients and cooling gloves imported from France and Sweden, potentially worsening chemotherapy-induced skin toxicity and increasing oncology support costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.
The rising incidence of cancer is expected to drive the growth of the hand-foot syndrome market. Cancer is a condition characterized by uncontrolled cell growth that spreads to other parts of the body. The increasing number of cancer cases is influenced by factors such as aging populations, lifestyle changes, environmental exposures, and advancements in detection methods. As cancer cases rise, chemotherapy usage also increases, leading to a higher prevalence of hand-foot syndrome, which is a common side effect of chemotherapy treatments. For example, in August 2024, Macmillan Cancer Support, a UK-based charity, reported that over 3 million people in the UK were living with cancer. This figure is projected to rise to 3.5 million by 2025, 4 million by 2030, and 5.3 million by 2040. As a result, the growing number of cancer cases will contribute to the expansion of the hand-foot syndrome market.
Companies operating in the hand-foot syndrome market are focusing on technological innovations such as image-guided radiotherapy (IGRT) to improve the precision and effectiveness of treatments, enhance patient outcomes, and minimize damage to healthy tissues. IGRT uses advanced imaging techniques to ensure accurate tumor targeting during radiation therapy, allowing real-time tracking and adjustment of the tumor's position. For instance, in May 2022, Elekta AB, a Sweden-based medical technology company, introduced the Elekta Esprit, a next-generation radiosurgery system that improves the capabilities of stereotactic radiosurgery. The Elekta Esprit integrates various innovations into a single platform, offering superior visualization and remote accessibility for treatment teams. It also supports flexible workflows, accommodating single-session, fractionated, adaptive, or staged protocols, all designed to improve efficiency and ease of use in clinical environments.
In June 2024, AstraZeneca Plc, a UK-based pharmaceutical company, acquired Fusion Pharmaceuticals Inc. for $2.5 billion. This acquisition aims to strengthen AstraZeneca's oncology portfolio with advanced radiopharmaceuticals, such as FPI-2265, enhance its research and development and manufacturing capabilities, and accelerate the transition to targeted cancer therapies while expanding its presence in Canada. Fusion Pharmaceuticals Inc. is a biotechnology company based in Canada that specializes in developing next-generation radiopharmaceuticals as precision medicines for cancer treatment.
Major players in the hand foot syndrome market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd., Merck & Co. Inc., AbbVie Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis International AG, Fresenius Kabi AG, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Regeneron Pharmaceuticals Inc., Astellas Pharma Inc., UCB Pharma SA, and Eisai Co. Ltd.
Asia-Pacific was the largest region in the hand food syndrome market in 2024. The regions covered in hand foot syndrome report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the hand foot syndrome market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The hand foot syndrome market consists of revenues earned by entities providing services such as treatments, therapies, and supportive care services for managing symptoms and complications of the condition. The market value includes the value of related goods sold by the service provider or included within the service offering. The hand foot syndrome market also includes sales of pharmaceutical drugs, topical treatments, and medical devices used to alleviate symptoms and manage the condition. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Hand Foot Syndrome Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on hand foot syndrome market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for hand foot syndrome ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The hand foot syndrome market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.