Liquid Chromatography Instruments Global Market Report 2026

Liquid chromatography instruments are mechanical devices employed to conduct liquid chromatography, a technique focused on separating a sample into its constituent parts based on interactions with the mobile and stationary phases.

The primary types of liquid chromatography instruments include high-performance liquid chromatography (HPLC), ultra-high pressure liquid chromatography (UHPLC), low-pressure liquid chromatography (LPLC), and fast protein liquid chromatography (FPLC). HPLC, for instance, involves pumping a sample mixture or analyte in a solvent (the mobile phase) at high pressure through a column with the stationary phase. These instruments find application in various fields, including clinical diagnostics, environmental testing, food and beverage analysis, forensic testing, and life sciences. End-users of liquid chromatography instruments span academics and research institutes, pharmaceutical companies, hospitals, the agriculture industry, and other sectors.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

Tariffs have affected the liquid chromatography instruments market by increasing the cost of imported detectors, pumps, columns, electronic components, and precision hardware used in LC system assembly. Pharmaceutical, environmental testing, and food analysis laboratories in North America and Europe face higher procurement costs due to reliance on globally sourced parts. However, tariffs are also prompting regional production of analytical components, fostering localized manufacturing, and stimulating innovation in cost-efficient chromatography technologies to improve long-term supply chain resilience.

The liquid chromatography instruments market research report is one of a series of new reports from The Business Research Company that provides liquid chromatography instruments market statistics, including liquid chromatography instruments industry global market size, regional shares, competitors with a liquid chromatography instruments market share, detailed liquid chromatography instruments market segments, market trends and opportunities, and any further data you may need to thrive in the liquid chromatography instruments industry. This liquid chromatography instruments market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The liquid chromatography instruments market size has grown strongly in recent years. It will grow from $5.71 billion in 2025 to $6.07 billion in 2026 at a compound annual growth rate (CAGR) of 6.3%. The growth in the historic period can be attributed to growth in pharmaceutical and biotech r&d, early use in environmental testing, expansion of clinical diagnostic tools, adoption in food quality analysis, reliance on traditional hplc systems.

The liquid chromatography instruments market size is expected to see strong growth in the next few years. It will grow to $7.69 billion in 2030 at a compound annual growth rate (CAGR) of 6.1%. The growth in the forecast period can be attributed to increasing adoption of advanced uhplc systems, expansion of life sciences research programs, rising demand for precision analytical instruments, development of high-throughput chromatography technologies, increasing use of lc systems in forensic and agricultural testing. Major trends in the forecast period include adoption of automated chromatography workflows, advancement of AI-enabled analytical platforms, integration of digitally connected lc instruments, expansion of intelligent laboratory management systems, development of smart data-driven chromatography solutions.

Rising cases of chronic diseases are expected to drive the growth of the liquid chromatography instruments market going forward. A chronic disease is a long-term health condition that persists for an extended period, typically a year or more, and often requires continuous medical management and care. Liquid chromatography instruments are used in diagnosing chronic diseases by separating and analyzing biological samples to detect specific biomarkers and compounds. For example, according to the American Cancer Society, a US-based health organization, the projected number of new cancer cases in the United States increased from approximately 1,918,030 in 2022 to 1,958,310 in 2023 (a growth of ~2.1%). The estimated number of cancer deaths rose slightly from about 609,360 in 2022 to 609,820 in 2023 (an increase of ~0.07%). Therefore, rising cases of chronic diseases are driving the liquid chromatography instruments market.

Major companies operating in the liquid chromatography instruments market are developing innovative products, such as intelligent high-performance liquid chromatography (HPLC) systems, to expand their customer base, increase sales, and boost revenue. An intelligent high-performance liquid chromatography (HPLC) system refers to an advanced chromatographic setup equipped with smart technologies and features that improve automation, precision, and efficiency in the analytical process. For instance, in March 2023, Waters Corporation, a US-based analytical laboratory instrument manufacturer, launched Alliance iS. Designed with advanced functionalities, the Alliance iS High-Performance Liquid Chromatography (HPLC) System minimizes compliance risks through proactive error detection, troubleshooting tools, and an intuitive user interface. When used with Waters' compliance-ready Empower Chromatography Software and eConnect HPLC Columns, the system transforms the process of achieving precise and accurate measurements by identifying and correcting common errors, leading to up to a 40% reduction in errors. The distinctive capabilities of the Alliance iS HPLC System help Quality Control (QC) laboratories consistently meet objectives related to quality, safety, compliance, and timely product delivery.

In February 2023, Waters Corporation, a US-based provider of analytical instruments and software-including chromatography and mass spectrometry systems-acquired Wyatt Technology for $1.36 billion. Through this acquisition, Waters aimed to strengthen its bioanalytical characterization capabilities and expand its portfolio into high-growth areas such as cell and gene therapies, thereby enhancing its competitive position within the chromatography instruments ecosystem. Wyatt Technology is a US-based provider of light-scattering and field-flow fractionation instruments, software, accessories, and services that complement liquid chromatography systems by offering advanced tools for molecular and nanoparticle analysis.

Major companies operating in the liquid chromatography instruments market are PerkinElmer Inc., Hitachi High-Tech Corporation, Waters Corporation, Bio-Rad Laboratories Inc., Agilent Technologies, Shimadzu Corporation, AB SCIEX, Bruker Corporation, Thermo Fisher Scientific Inc., Phenomenex Inc., GE HealthCare Technologies Inc., Merck KGaA, Hamilton Company, Gilson Incorporated, Trajan Scientific and Medical Pty Ltd., Restek Corporation, Showa Denko K.K., SIELC Technologies Inc., Orochem Technologies Inc., Tosoh Corporation, GL Sciences Inc., KNAUER Wissenschaftliche Gerate GmbH, Sepax Technologies Inc., Daicel Corporation, Mitsubishi Chemical Corporation, Agela Technologies Inc., Advanced Materials Technology Inc., Chrom Tech Inc., EMD Millipore Corporation, Hichrom Limited, Imtakt Corporation, Kinesis Ltd., MAC-MOD Analytical Inc., Regis Technologies Inc., VWR International LLC, W.R. Grace & Co.

North America was the largest region in the liquid chromatography instruments market in 2025. Asia-Pacific is expected to be the fastest-growing region in the liquid chromatography instruments market report during the forecast period. The regions covered in the liquid chromatography instruments market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the liquid chromatography instruments market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The liquid chromatography instruments market consists of sales of solvent inlet filters, pumps, inline solvent filters, injection valves, pre-column filters, columns, detectors, recorders, backpressure regulators, and waste reservoirs. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Liquid Chromatography Instruments Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses liquid chromatography instruments market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

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Where is the largest and fastest growing market for liquid chromatography instruments ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The liquid chromatography instruments market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

• The market characteristics section of the report defines and explains the market. This section also examines key products and services offered in the market, evaluates brand-level differentiation, compares product features, and highlights major innovation and product development trends.
• The supply chain analysis section provides an overview of the entire value chain, including key raw materials, resources, and supplier analysis. It also provides a list competitor at each level of the supply chain.
• The updated trends and strategies section analyses the shape of the market as it evolves and highlights emerging technology trends such as digital transformation, automation, sustainability initiatives, and AI-driven innovation. It suggests how companies can leverage these advancements to strengthen their market position and achieve competitive differentiation.
• The regulatory and investment landscape section provides an overview of the key regulatory frameworks, regularity bodies, associations, and government policies influencing the market. It also examines major investment flows, incentives, and funding trends shaping industry growth and innovation.
• The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
• The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
• The total addressable market (TAM) analysis section defines and estimates the market potential compares it with the current market size, and provides strategic insights and growth opportunities based on this evaluation.
• The market attractiveness scoring section evaluates the market based on a quantitative scoring framework that considers growth potential, competitive dynamics, strategic fit, and risk profile. It also provides interpretive insights and strategic implications for decision-makers.
• Market segmentations break down the market into sub markets.
• The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
• Expanded geographical coverage includes Taiwan and Southeast Asia, reflecting recent supply chain realignments and manufacturing shifts in the region. This section analyzes how these markets are becoming increasingly important hubs in the global value chain.
• The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
• The company scoring matrix section evaluates and ranks leading companies based on a multi-parameter framework that includes market share or revenues, product innovation, and brand recognition.

Scope

• Markets Covered:1) By Type: High Performance Liquid Chromatography (HPLC); Ultra High Pressure Liquid Chromatography (UHPLC); Low Pressure Liquid Chromatography (LPLC); Fast Protein Liquid Chromatography (FPLC)
• 2) By Application: Clinical Diagnostics; Environmental Testing; Food And Beverage Analysis; Forensic Tests; Life Sciences
• 3) By End-User: Academics And Research Institutes; Pharmaceutical Companies; Hospitals; Agriculture Industry; Other End-User
• Subsegments:
• 1) By High Performance Liquid Chromatography (HPLC): Reverse Phase HPLC; Normal Phase HPLC; Ion-Exchange HPLC; Size Exclusion HPLC
• 2) By Ultra High Pressure Liquid Chromatography (UHPLC): Ultra-Fast LC; Core-Shell Particle LC; Sub-2 Micron Particle LC
• 3) By Low Pressure Liquid Chromatography (LPLC): Gel Filtration Chromatography; Ion-Exchange Chromatography; Affinity Chromatography
• 4) By Fast Protein Liquid Chromatography (FPLC): Ion-Exchange FPLC; Affinity FPLC; Size Exclusion FPLC
• Companies Mentioned: PerkinElmer Inc.; Hitachi High-Tech Corporation; Waters Corporation; Bio-Rad Laboratories Inc.; Agilent Technologies; Shimadzu Corporation; AB SCIEX; Bruker Corporation; Thermo Fisher Scientific Inc.; Phenomenex Inc.; GE HealthCare Technologies Inc.; Merck KGaA; Hamilton Company; Gilson Incorporated; Trajan Scientific and Medical Pty Ltd.; Restek Corporation; Showa Denko K.K.; SIELC Technologies Inc.; Orochem Technologies Inc.; Tosoh Corporation; GL Sciences Inc.; KNAUER Wissenschaftliche Gerate GmbH; Sepax Technologies Inc.; Daicel Corporation; Mitsubishi Chemical Corporation; Agela Technologies Inc.; Advanced Materials Technology Inc.; Chrom Tech Inc.; EMD Millipore Corporation; Hichrom Limited; Imtakt Corporation; Kinesis Ltd.; MAC-MOD Analytical Inc.; Regis Technologies Inc.; VWR International LLC; W.R. Grace & Co.
• Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Taiwan; Russia; South Korea; UK; USA; Canada; Italy; Spain.
• Regions: Asia-Pacific; South East Asia; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
• Time Series: Five years historic and ten years forecast.
• Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
• Data Segmentations: country and regional historic and forecast data, market share of competitors, market segments.
• Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
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