PUBLISHER: The Business Research Company | PRODUCT CODE: 1998101
PUBLISHER: The Business Research Company | PRODUCT CODE: 1998101
Protein engineering is a process wherein researchers modify protein sequences by substituting, inserting, or deleting nucleotides within the encoding gene. The objective is to obtain modified proteins better suited for specific applications or purposes compared to unmodified proteins.
The primary products and services in protein engineering encompass instruments, reagents, services, and software. Instruments are tools or devices used for scientific tasks related to protein engineering, leading to alterations in the protein backbone. The proteins involved in this process include insulin, monoclonal antibodies, coagulation factors, vaccines, growth factors, and others. The technologies utilized include irrational protein design and rational protein design. Protein engineering finds applications in pharmaceutical and biotechnology companies, academic research institutes, and contract research organizations.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
Tariffs are impacting the protein engineering market by increasing costs of imported laboratory instruments, reagents, analytical equipment, and software tools used in protein design and modification. Research-intensive regions in North America and Europe are most affected due to reliance on global suppliers, while Asia-Pacific faces cost pressures in exporting engineered proteins. These tariffs are raising research expenditures and project timelines. However, they are also encouraging domestic manufacturing of research tools, regional software development, and localized service capabilities.
The protein engineering market research report is one of a series of new reports from The Business Research Company that provides protein engineering market statistics, including protein engineering industry global market size, regional shares, competitors with a protein engineering market share, detailed protein engineering market segments, market trends and opportunities, and any further data you may need to thrive in the protein engineering industry. This protein engineering market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The protein engineering market size has grown rapidly in recent years. It will grow from $4.62 billion in 2025 to $5.31 billion in 2026 at a compound annual growth rate (CAGR) of 14.8%. The growth in the historic period can be attributed to expansion of biopharmaceutical research activities, increasing availability of advanced laboratory instruments, growth in academic protein research, rising investments in biotechnology, improvements in protein characterization methods.
The protein engineering market size is expected to see rapid growth in the next few years. It will grow to $9.3 billion in 2030 at a compound annual growth rate (CAGR) of 15.1%. The growth in the forecast period can be attributed to increasing demand for next-generation biologics, expansion of personalized medicine, growing use of engineered proteins in vaccines, rising adoption of computational biology, increasing collaboration between industry and academia. Major trends in the forecast period include increasing adoption of rational protein design techniques, rising use of ai in protein modeling, growing demand for engineered therapeutic proteins, expansion of custom protein engineering services, enhanced integration of bioinformatics tools.
The escalating demand for protein-based drugs is a key driver fueling the growth of the protein engineering market. These drugs, derived from proteins and utilized for therapeutic purposes, are genetically engineered versions of naturally occurring human proteins. Protein engineering techniques involve modifying protein sequences by altering nucleotides within their encoding genes. This alteration aims to tailor protein-based drugs to specific applications, optimizing their effectiveness. For instance, a study published in the Lancet Diabetes and Endocrinology journal forecasts a 20% increase, reaching nearly 80 million individuals requiring insulin for type-2 diabetes by 2030. This burgeoning demand underscores the impetus driving the protein engineering market.
Key players in the protein engineering market are creating innovative products using advanced technologies, such as the SUREtechnology platform, to improve the stability, efficacy, and manufacturability of therapeutic proteins. The SUREtechnology platform allows for precise modifications, facilitating the production of next-generation biologics with enhanced therapeutic properties, minimized side effects, and increased production efficiency. For example, in September 2023, KBI Biopharma, a US-based biotechnology company, introduced SUREmAb, an innovative solution developed on its SUREtechnology platform. This product focuses on the optimized, safe, and cost-effective development and manufacturing of monoclonal antibodies (mAb), addressing the growing demand for biopharmaceuticals. SUREmAb enables rapid progress from transfection to Research Cell Bank (RCB) in as little as nine weeks and allows for drug substance release within 11 months.
In July 2024, Fortifi, a US-based food processing company, acquired Les Innovations Mecaniques Alimentaires for an undisclosed amount. By incorporating LIMA into its operations, Fortifi aims to reinforce its leadership position in the food processing equipment market, boosting its competitiveness and market share. Les Innovations Mecaniques Alimentaires is a France-based manufacturer of protein processing equipment.
Major companies operating in the protein engineering market are Codexis Inc., GenScript Biotech Corporation, Abzena plc, Aragen Bioscience Inc., Enantis s.r.o., Creative BioMart, Twist Bioscience Corporation, Ginkgo Bioworks Inc., Amyris Inc., Absci Corporation, Generate Biomedicines Inc., ProteinQure Inc., Zymeworks Inc., Adimab LLC, Ichnos Sciences SA, Synthego Corporation, Evotec SE, Pieris Pharmaceuticals Inc., MacroGenics Inc., Adagene Inc.
North America was the largest region in the protein engineering market share in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the protein engineering market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the protein engineering market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Italy, Spain, Canada
The protein engineering market consists of revenues earned by entities by providing protein engineering services through use of enzymes, interleukins, and thrombolytics. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Protein Engineering Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses protein engineering market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for protein engineering ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The protein engineering market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
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