PUBLISHER: Grand View Research | PRODUCT CODE: 1908648
PUBLISHER: Grand View Research | PRODUCT CODE: 1908648
The global gRNA market size was estimated at USD 579.5 million in 2024 and is projected to reach USD 2.66 billion by 2033, growing at a CAGR of 18.64% from 2025 to 2033. gRNA is in high demand because it is essential for CRISPR-based genetic editing.
Its ability to accurately guide the CRISPR system to specific DNA sequences enables precise gene modifications, driving breakthroughs in medicine, agriculture, and biotechnology.
Expansion of CRISPR Gene Editing Applications
The global demand for gRNA is rising sharply due to the rapid expansion of CRISPR applications across research and industry. As the critical element that directs CRISPR to specific DNA or RNA targets, every CRISPR workflow depends on precise and reliable gRNA. Increasing use of CRISPR in functional genomics, knockout/knock-in studies, engineered cell models, and high-throughput screening has driven strong growth in customized gRNA consumption. With CRISPR advancing from research to clinical and therapeutic applications, especially in gene therapy and precision medicine, more biopharma and academic labs are adopting the technology, further escalating the need for specialized gRNA. For instance, in October 2021, in Germany, Merck licensed its patented CRISPR-Cas9 technology to Cellecta, enabling advanced knock-in applications.
The growing diversification of CRISPR systems is further boosting demand for tailored gRNA products. As gene-editing advances from traditional Cas9 to next-generation tools like Cas12 and Cas13 for RNA targeting, for compact delivery, and platforms such as base and prime editing, researchers require highly optimized gRNAs with greater efficiency and minimal off-target effects.
Global gRNA Market Report Segmentation
This report forecasts revenue growth and provides an analysis of the latest trends in each of the sub-segments from 2021 to 2033. For this report, Grand View Research has segmented the global gRNA market report based on product & services, gRNA type, application, end-use, and region: