gRNA Market- Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Type, By Product & Services (Product, Custom gRNA Synthesis Services), By Application, By End-Use, By Region and Competition, 2020-2030F

Description

The Global gRNA Market, valued at USD 559.00 Million in 2024, is projected to experience a CAGR of 19.20% to reach USD 1603.52 Million by 2030. Guide RNA (gRNA) is a synthetic RNA molecule serving as a pivotal component within the CRISPR-Cas9 genome editing system, precisely directing the Cas9 nuclease to target specific DNA sequences for modification. The global gRNA market's growth is primarily driven by significant advancements in gene editing technologies, the increasing global prevalence of genetic disorders leading to higher demand for novel gene therapies, and expanding applications across biomedical research and agriculture. Substantial investment in biotechnology research and development further propels market expansion.

Market Overview
Forecast Period	2026-2030
Market Size 2024	USD 559.00 Million
Market Size 2030	USD 1603.52 Million
CAGR 2025-2030	19.20%
Fastest Growing Segment	Pharmaceutical & Biotechnology Companies
Largest Market	North America

Key Market Drivers

The global gRNA market's expansion is significantly propelled by the widespread adoption of CRISPR-Cas systems for gene editing, a foundational technology that gRNA molecules directly enable. The increasing clinical validation and commercialization of CRISPR-based therapies exemplify this adoption. For instance, according to Vertex's Q3 2024 financial report, 40 individuals have entered the treatment process for Casgevy, the first approved CRISPR-based medicine, demonstrating tangible progress in patient access and therapeutic application.

Key Market Challenges

The complex and heterogeneous global regulatory landscape represents a significant impediment to the growth of the Global gRNA Market. Diverse national and regional regulations necessitate extensive and often duplicative processes for product approval, directly escalating development costs and extending timelines for commercialization. This regulatory fragmentation consumes substantial financial and human resources, which could otherwise be directed towards scientific innovation and market penetration. The inherent uncertainty and varying requirements across jurisdictions also deter investment, particularly from smaller entities, thereby limiting the pipeline of novel gRNA-based applications.

Key Market Trends

The emergence of GMP-grade gRNA for clinical applications represents a pivotal shift as gene editing technologies transition from research to therapeutic products, necessitating stringent Good Manufacturing Practice standards for gRNA molecules. This ensures the safety, purity, and efficacy of gene therapies entering trials and the market. The escalating pipeline of gene therapy candidates directly fuels demand for high-quality gRNA manufacturing solutions.

Key Market Players

Thermo Fisher Scientific Inc.
Agilent Technologies, Inc.
System Biosciences, LLC
Jena Bioscience GmbH
Merck KGaA
Azenta US, Inc.
Takara Bio, Inc.
Synbio Technologies
Revvity, Inc.
Synthego Corporation

Report Scope:

In this report, the Global gRNA Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

gRNA Market, By Type:

Research-Use
GMP-grade

gRNA Market, By Product & Services:

Product
Custom gRNA Synthesis Services

gRNA Market, By Application:

Genome Engineering
Disease Model Studies
Functional Genomics
Epigenetics
Others

gRNA Market, By End Use:

Pharmaceutical & Biotechnology Companies
Academic Research Institutes
CMOs & CROs

gRNA Market, By Region:

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global gRNA Market.

Available Customizations:

Global gRNA Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global gRNA Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Type (Research-Use, GMP-grade)
- 5.2.2. By Product & Services (Product, Custom gRNA Synthesis Services)
- 5.2.3. By Application (Genome Engineering, Disease Model Studies, Functional Genomics, Epigenetics, Others)
- 5.2.4. By End Use (Pharmaceutical & Biotechnology Companies, Academic Research Institutes, CMOs & CROs)
- 5.2.5. By Region
- 5.2.6. By Company (2024)
5.3. Market Map

6. North America gRNA Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Type
- 6.2.2. By Product & Services
- 6.2.3. By Application
- 6.2.4. By End Use
- 6.2.5. By Country
6.3. North America: Country Analysis
- 6.3.1. United States gRNA Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Type
    - 6.3.1.2.2. By Product & Services
    - 6.3.1.2.3. By Application
    - 6.3.1.2.4. By End Use
- 6.3.2. Canada gRNA Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Type
    - 6.3.2.2.2. By Product & Services
    - 6.3.2.2.3. By Application
    - 6.3.2.2.4. By End Use
- 6.3.3. Mexico gRNA Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Type
    - 6.3.3.2.2. By Product & Services
    - 6.3.3.2.3. By Application
    - 6.3.3.2.4. By End Use

7. Europe gRNA Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Type
- 7.2.2. By Product & Services
- 7.2.3. By Application
- 7.2.4. By End Use
- 7.2.5. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany gRNA Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Type
    - 7.3.1.2.2. By Product & Services
    - 7.3.1.2.3. By Application
    - 7.3.1.2.4. By End Use
- 7.3.2. France gRNA Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Type
    - 7.3.2.2.2. By Product & Services
    - 7.3.2.2.3. By Application
    - 7.3.2.2.4. By End Use
- 7.3.3. United Kingdom gRNA Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Type
    - 7.3.3.2.2. By Product & Services
    - 7.3.3.2.3. By Application
    - 7.3.3.2.4. By End Use
- 7.3.4. Italy gRNA Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Type
    - 7.3.4.2.2. By Product & Services
    - 7.3.4.2.3. By Application
    - 7.3.4.2.4. By End Use
- 7.3.5. Spain gRNA Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Type
    - 7.3.5.2.2. By Product & Services
    - 7.3.5.2.3. By Application
    - 7.3.5.2.4. By End Use

8. Asia Pacific gRNA Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Type
- 8.2.2. By Product & Services
- 8.2.3. By Application
- 8.2.4. By End Use
- 8.2.5. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China gRNA Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Type
    - 8.3.1.2.2. By Product & Services
    - 8.3.1.2.3. By Application
    - 8.3.1.2.4. By End Use
- 8.3.2. India gRNA Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Type
    - 8.3.2.2.2. By Product & Services
    - 8.3.2.2.3. By Application
    - 8.3.2.2.4. By End Use
- 8.3.3. Japan gRNA Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Type
    - 8.3.3.2.2. By Product & Services
    - 8.3.3.2.3. By Application
    - 8.3.3.2.4. By End Use
- 8.3.4. South Korea gRNA Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Type
    - 8.3.4.2.2. By Product & Services
    - 8.3.4.2.3. By Application
    - 8.3.4.2.4. By End Use
- 8.3.5. Australia gRNA Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Type
    - 8.3.5.2.2. By Product & Services
    - 8.3.5.2.3. By Application
    - 8.3.5.2.4. By End Use

9. Middle East & Africa gRNA Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Type
- 9.2.2. By Product & Services
- 9.2.3. By Application
- 9.2.4. By End Use
- 9.2.5. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia gRNA Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Type
    - 9.3.1.2.2. By Product & Services
    - 9.3.1.2.3. By Application
    - 9.3.1.2.4. By End Use
- 9.3.2. UAE gRNA Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Type
    - 9.3.2.2.2. By Product & Services
    - 9.3.2.2.3. By Application
    - 9.3.2.2.4. By End Use
- 9.3.3. South Africa gRNA Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Type
    - 9.3.3.2.2. By Product & Services
    - 9.3.3.2.3. By Application
    - 9.3.3.2.4. By End Use

10. South America gRNA Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Type
- 10.2.2. By Product & Services
- 10.2.3. By Application
- 10.2.4. By End Use
- 10.2.5. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil gRNA Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Type
    - 10.3.1.2.2. By Product & Services
    - 10.3.1.2.3. By Application
    - 10.3.1.2.4. By End Use
- 10.3.2. Colombia gRNA Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Type
    - 10.3.2.2.2. By Product & Services
    - 10.3.2.2.3. By Application
    - 10.3.2.2.4. By End Use
- 10.3.3. Argentina gRNA Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Type
    - 10.3.3.2.2. By Product & Services
    - 10.3.3.2.3. By Application
    - 10.3.3.2.4. By End Use

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global gRNA Market: SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Thermo Fisher Scientific Inc.
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. Agilent Technologies, Inc.
15.3. System Biosciences, LLC
15.4. Jena Bioscience GmbH
15.5. Merck KGaA
15.6. Azenta US, Inc.
15.7. Takara Bio, Inc.
15.8. Synbio Technologies
15.9. Revvity, Inc.
15.10. Synthego Corporation