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PUBLISHER: IMARC | PRODUCT CODE: 1722832

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PUBLISHER: IMARC | PRODUCT CODE: 1722832

Protein Engineering Market Size, Share, Trends and Forecast by Product & Services, Protein Type, Technology, End User and Region, 2025-2033

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The global protein engineering market size was valued at USD 3.6 Billion in 2024. Looking forward, IMARC Group estimates the market to reach USD 8.2 Billion by 2033, exhibiting a CAGR of 9.5% during 2025-2033. North America currently dominates the market, holding a significant market share of 40.6% in 2024. Artificial intelligence (AI-driven) automation enhances protein modeling, drug discovery, and industrial enzyme optimization, which is a key factor expanding the protein engineering market share. Government funding supports academic research, accelerating innovations in protein therapeutics and synthetic biology.

Protein engineering refers to the process of developing or changing a protein sequence to achieve the desired result. It involves the synthesis of new proteins or amendments in the existing structure or sequence and employs recombinant deoxyribonucleic acid (DNA) technology to alter amino acid sequences for novel and enhanced functions. It is widely utilized for the production of enzymes or proteins in large quantities for use in industrial settings. In recent years, researchers have successfully engineered a wide range of proteins tailored to medicine, research, industry, health, and biotechnology applications, which is escalating their demand across the globe.

Protein Engineering Market Trends:

The rising investments in synthetic biology and the improving focus toward protein-based drug development represent the primary factors driving the market growth. Additionally, there has been a significant shift toward protein therapeutics from non-protein drugs due to their associated positive clinical outcomes. This, in confluence with the widespread prevalence of protein-deficient diseases, is increasing the demand for protein engineering. Furthermore, several favorable initiatives undertaken by the government of various countries, such as increased funding for research and development (R&D) activities in the field of protein engineering, are propelling the market growth. Besides this, the advent of recombinant monoclonal antibodies (mAbs) and the increasing usage of monoclonal antibodies to treat various diseases, such as cancer and autoimmune diseases, are accelerating product adoption rates. Moreover, the ongoing research for applications of protein engineering in the agrochemical industry to generate enzymes with enhanced function to increase the crop yield or facilitate biofuel production is catalyzing the market growth. Other factors, including the escalating demand for personalized medicines, growing need for biosimilars and biologics, improving healthcare infrastructure, technological advancements, and product innovations, are also creating a positive outlook for the market.

Key Market Segmentation:

Breakup by Product & Services:

  • Instruments
  • Reagents
  • Services and Software

Breakup by Protein Type:

  • Insulin
  • Monoclonal Antibodies
  • Coagulation Factors
  • Vaccines
  • Growth Factors
  • Others

Breakup by Technology:

  • Irrational Protein Design
  • Rational Protein Design

Breakup by End User:

  • Pharmaceutical and Biotechnology Companies
  • Academic Research Institutes
  • Contract Research Organizations

Breakup by Region:

  • North America
  • United States
  • Canada
  • Asia-Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
  • Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • Others
  • Latin America
  • Brazil
  • Mexico
  • Others
  • Middle East and Africa

Competitive Landscape:

The competitive landscape of the industry has also been examined along with the profiles of the key players being Abzena Ltd., Agilent Technologies Inc., Amgen Inc., Bio-Rad Laboratories Inc., Bruker Corporation, Codexis Inc., Danaher Corporation, Eli Lilly and Company, General Electric Company, Merck KGaA, Novo Nordisk A/S, PerkinElmer Inc., Thermo Fisher Scientific Inc. and Waters Corporation.

Key Questions Answered in This Report

  • 1.How big is the protein engineering market?
  • 2.What is the future outlook of protein engineering market?
  • 3.What are the key factors driving the protein engineering market?
  • 4.Which region accounts for the largest protein engineering market share?
  • 5.Which are the leading companies in the global protein engineering market?
Product Code: SR112025A5005

Table of Contents

1 Preface

2 Scope and Methodology

  • 2.1 Objectives of the Study
  • 2.2 Stakeholders
  • 2.3 Data Sources
    • 2.3.1 Primary Sources
    • 2.3.2 Secondary Sources
  • 2.4 Market Estimation
    • 2.4.1 Bottom-Up Approach
    • 2.4.2 Top-Down Approach
  • 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

  • 4.1 Overview
  • 4.2 Key Industry Trends

5 Global Protein Engineering Market

  • 5.1 Market Overview
  • 5.2 Market Performance
  • 5.3 Impact of COVID-19
  • 5.4 Market Forecast

6 Market Breakup by Product & Services

  • 6.1 Instruments
    • 6.1.1 Market Trends
    • 6.1.2 Market Forecast
  • 6.2 Reagents
    • 6.2.1 Market Trends
    • 6.2.2 Market Forecast
  • 6.3 Services and Software
    • 6.3.1 Market Trends
    • 6.3.2 Market Forecast

7 Market Breakup by Protein Type

  • 7.1 Insulin
    • 7.1.1 Market Trends
    • 7.1.2 Market Forecast
  • 7.2 Monoclonal Antibodies
    • 7.2.1 Market Trends
    • 7.2.2 Market Forecast
  • 7.3 Coagulation Factors
    • 7.3.1 Market Trends
    • 7.3.2 Market Forecast
  • 7.4 Vaccines
    • 7.4.1 Market Trends
    • 7.4.2 Market Forecast
  • 7.5 Growth Factors
    • 7.5.1 Market Trends
    • 7.5.2 Market Forecast
  • 7.6 Others
    • 7.6.1 Market Trends
    • 7.6.2 Market Forecast

8 Market Breakup by Technology

  • 8.1 Irrational Protein Design
    • 8.1.1 Market Trends
    • 8.1.2 Market Forecast
  • 8.2 Rational Protein Design
    • 8.2.1 Market Trends
    • 8.2.2 Market Forecast

9 Market Breakup by End User

  • 9.1 Pharmaceutical and Biotechnology Companies
    • 9.1.1 Market Trends
    • 9.1.2 Market Forecast
  • 9.2 Academic Research Institutes
    • 9.2.1 Market Trends
    • 9.2.2 Market Forecast
  • 9.3 Contract Research Organizations
    • 9.3.1 Market Trends
    • 9.3.2 Market Forecast

10 Market Breakup by Region

  • 10.1 North America
    • 10.1.1 United States
      • 10.1.1.1 Market Trends
      • 10.1.1.2 Market Forecast
    • 10.1.2 Canada
      • 10.1.2.1 Market Trends
      • 10.1.2.2 Market Forecast
  • 10.2 Asia-Pacific
    • 10.2.1 China
      • 10.2.1.1 Market Trends
      • 10.2.1.2 Market Forecast
    • 10.2.2 Japan
      • 10.2.2.1 Market Trends
      • 10.2.2.2 Market Forecast
    • 10.2.3 India
      • 10.2.3.1 Market Trends
      • 10.2.3.2 Market Forecast
    • 10.2.4 South Korea
      • 10.2.4.1 Market Trends
      • 10.2.4.2 Market Forecast
    • 10.2.5 Australia
      • 10.2.5.1 Market Trends
      • 10.2.5.2 Market Forecast
    • 10.2.6 Indonesia
      • 10.2.6.1 Market Trends
      • 10.2.6.2 Market Forecast
    • 10.2.7 Others
      • 10.2.7.1 Market Trends
      • 10.2.7.2 Market Forecast
  • 10.3 Europe
    • 10.3.1 Germany
      • 10.3.1.1 Market Trends
      • 10.3.1.2 Market Forecast
    • 10.3.2 France
      • 10.3.2.1 Market Trends
      • 10.3.2.2 Market Forecast
    • 10.3.3 United Kingdom
      • 10.3.3.1 Market Trends
      • 10.3.3.2 Market Forecast
    • 10.3.4 Italy
      • 10.3.4.1 Market Trends
      • 10.3.4.2 Market Forecast
    • 10.3.5 Spain
      • 10.3.5.1 Market Trends
      • 10.3.5.2 Market Forecast
    • 10.3.6 Russia
      • 10.3.6.1 Market Trends
      • 10.3.6.2 Market Forecast
    • 10.3.7 Others
      • 10.3.7.1 Market Trends
      • 10.3.7.2 Market Forecast
  • 10.4 Latin America
    • 10.4.1 Brazil
      • 10.4.1.1 Market Trends
      • 10.4.1.2 Market Forecast
    • 10.4.2 Mexico
      • 10.4.2.1 Market Trends
      • 10.4.2.2 Market Forecast
    • 10.4.3 Others
      • 10.4.3.1 Market Trends
      • 10.4.3.2 Market Forecast
  • 10.5 Middle East and Africa
    • 10.5.1 Market Trends
    • 10.5.2 Market Breakup by Country
    • 10.5.3 Market Forecast

11 SWOT Analysis

  • 11.1 Overview
  • 11.2 Strengths
  • 11.3 Weaknesses
  • 11.4 Opportunities
  • 11.5 Threats

12 Value Chain Analysis

13 Porters Five Forces Analysis

  • 13.1 Overview
  • 13.2 Bargaining Power of Buyers
  • 13.3 Bargaining Power of Suppliers
  • 13.4 Degree of Competition
  • 13.5 Threat of New Entrants
  • 13.6 Threat of Substitutes

14 Price Analysis

15 Competitive Landscape

  • 15.1 Market Structure
  • 15.2 Key Players
  • 15.3 Profiles of Key Players
    • 15.3.1 Abzena Ltd.
      • 15.3.1.1 Company Overview
      • 15.3.1.2 Product Portfolio
    • 15.3.2 Agilent Technologies Inc.
      • 15.3.2.1 Company Overview
      • 15.3.2.2 Product Portfolio
      • 15.3.2.3 Financials
      • 15.3.2.4 SWOT Analysis
    • 15.3.3 Amgen Inc.
      • 15.3.3.1 Company Overview
      • 15.3.3.2 Product Portfolio
      • 15.3.3.3 Financials
      • 15.3.3.4 SWOT Analysis
    • 15.3.4 Bio-Rad Laboratories Inc.
      • 15.3.4.1 Company Overview
      • 15.3.4.2 Product Portfolio
      • 15.3.4.3 Financials
      • 15.3.4.4 SWOT Analysis
    • 15.3.5 Bruker Corporation
      • 15.3.5.1 Company Overview
      • 15.3.5.2 Product Portfolio
      • 15.3.5.3 Financials
      • 15.3.5.4 SWOT Analysis
    • 15.3.6 Codexis Inc.
      • 15.3.6.1 Company Overview
      • 15.3.6.2 Product Portfolio
      • 15.3.6.3 Financials
      • 15.3.6.4 SWOT Analysis
    • 15.3.7 Danaher Corporation
      • 15.3.7.1 Company Overview
      • 15.3.7.2 Product Portfolio
      • 15.3.7.3 Financials
      • 15.3.7.4 SWOT Analysis
    • 15.3.8 Eli Lilly and Company
      • 15.3.8.1 Company Overview
      • 15.3.8.2 Product Portfolio
      • 15.3.8.3 Financials
      • 15.3.8.4 SWOT Analysis
    • 15.3.9 General Electric Company
      • 15.3.9.1 Company Overview
      • 15.3.9.2 Product Portfolio
      • 15.3.9.3 Financials
      • 15.3.9.4 SWOT Analysis
    • 15.3.10 Merck KGaA
      • 15.3.10.1 Company Overview
      • 15.3.10.2 Product Portfolio
      • 15.3.10.3 Financials
      • 15.3.10.4 SWOT Analysis
    • 15.3.11 Novo Nordisk A/S
      • 15.3.11.1 Company Overview
      • 15.3.11.2 Product Portfolio
      • 15.3.11.3 Financials
      • 15.3.11.4 SWOT Analysis
    • 15.3.12 PerkinElmer Inc.
      • 15.3.12.1 Company Overview
      • 15.3.12.2 Product Portfolio
      • 15.3.12.3 Financials
      • 15.3.12.4 SWOT Analysis
    • 15.3.13 Thermo Fisher Scientific Inc.
      • 15.3.13.1 Company Overview
      • 15.3.13.2 Product Portfolio
      • 15.3.13.3 Financials
      • 15.3.13.4 SWOT Analysis
    • 15.3.14 Waters Corporation
      • 15.3.14.1 Company Overview
      • 15.3.14.2 Product Portfolio
      • 15.3.14.3 Financials
      • 15.3.14.4 SWOT Analysis
Product Code: SR112025A5005

List of Figures

  • Figure 1: Global: Protein Engineering Market: Major Drivers and Challenges
  • Figure 2: Global: Protein Engineering Market: Sales Value (in Billion USD), 2019-2024
  • Figure 3: Global: Protein Engineering Market Forecast: Sales Value (in Billion USD), 2025-2033
  • Figure 4: Global: Protein Engineering Market: Breakup by Product & Services (in %), 2024
  • Figure 5: Global: Protein Engineering Market: Breakup by Protein Type (in %), 2024
  • Figure 6: Global: Protein Engineering Market: Breakup by Technology (in %), 2024
  • Figure 7: Global: Protein Engineering Market: Breakup by End User (in %), 2024
  • Figure 8: Global: Protein Engineering Market: Breakup by Region (in %), 2024
  • Figure 9: Global: Protein Engineering (Instruments) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 10: Global: Protein Engineering (Instruments) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 11: Global: Protein Engineering (Reagents) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 12: Global: Protein Engineering (Reagents) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 13: Global: Protein Engineering (Services and Software) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 14: Global: Protein Engineering (Services and Software) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 15: Global: Protein Engineering (Insulin) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 16: Global: Protein Engineering (Insulin) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 17: Global: Protein Engineering (Monoclonal Antibodies) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 18: Global: Protein Engineering (Monoclonal Antibodies) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 19: Global: Protein Engineering (Coagulation Factors) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 20: Global: Protein Engineering (Coagulation Factors) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 21: Global: Protein Engineering (Vaccines) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 22: Global: Protein Engineering (Vaccines) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 23: Global: Protein Engineering (Growth Factors) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 24: Global: Protein Engineering (Growth Factors) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 25: Global: Protein Engineering (Other Protein Types) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 26: Global: Protein Engineering (Other Protein Types) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 27: Global: Protein Engineering (Irrational Protein Design) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 28: Global: Protein Engineering (Irrational Protein Design) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 29: Global: Protein Engineering (Rational Protein Design) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 30: Global: Protein Engineering (Rational Protein Design) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 31: Global: Protein Engineering (Pharmaceutical and Biotechnology Companies) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 32: Global: Protein Engineering (Pharmaceutical and Biotechnology Companies) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 33: Global: Protein Engineering (Academic Research Institutes) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 34: Global: Protein Engineering (Academic Research Institutes) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 35: Global: Protein Engineering (Contract Research Organizations) Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 36: Global: Protein Engineering (Contract Research Organizations) Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 37: North America: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 38: North America: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 39: United States: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 40: United States: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 41: Canada: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 42: Canada: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 43: Asia-Pacific: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 44: Asia-Pacific: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 45: China: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 46: China: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 47: Japan: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 48: Japan: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 49: India: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 50: India: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 51: South Korea: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 52: South Korea: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 53: Australia: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 54: Australia: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 55: Indonesia: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 56: Indonesia: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 57: Others: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 58: Others: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 59: Europe: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 60: Europe: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 61: Germany: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 62: Germany: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 63: France: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 64: France: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 65: United Kingdom: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 66: United Kingdom: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 67: Italy: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 68: Italy: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 69: Spain: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 70: Spain: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 71: Russia: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 72: Russia: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 73: Others: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 74: Others: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 75: Latin America: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 76: Latin America: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 77: Brazil: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 78: Brazil: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 79: Mexico: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 80: Mexico: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 81: Others: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 82: Others: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 83: Middle East and Africa: Protein Engineering Market: Sales Value (in Million USD), 2019 & 2024
  • Figure 84: Middle East and Africa: Protein Engineering Market: Breakup by Country (in %), 2024
  • Figure 85: Middle East and Africa: Protein Engineering Market Forecast: Sales Value (in Million USD), 2025-2033
  • Figure 86: Global: Protein Engineering Industry: SWOT Analysis
  • Figure 87: Global: Protein Engineering Industry: Value Chain Analysis
  • Figure 88: Global: Protein Engineering Industry: Porter's Five Forces Analysis

List of Tables

  • Table 1: Global: Protein Engineering Market: Key Industry Highlights, 2024 and 2033
  • Table 2: Global: Protein Engineering Market Forecast: Breakup by Product & Services (in Million USD), 2025-2033
  • Table 3: Global: Protein Engineering Market Forecast: Breakup by Protein Type (in Million USD), 2025-2033
  • Table 4: Global: Protein Engineering Market Forecast: Breakup by Technology (in Million USD), 2025-2033
  • Table 5: Global: Protein Engineering Market Forecast: Breakup by End User (in Million USD), 2025-2033
  • Table 6: Global: Protein Engineering Market Forecast: Breakup by Region (in Million USD), 2025-2033
  • Table 7: Global: Protein Engineering Market: Competitive Structure
  • Table 8: Global: Protein Engineering Market: Key Players
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