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Market Research Report

Autoimmune Disease Diagnosis Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2021-2026

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Autoimmune Disease Diagnosis Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2021-2026
Published: February 2, 2021 Content info: 142 Pages
Description

The global autoimmune disease diagnosis market reached a value of US$ 4.4 Billion in 2020. An autoimmune disease refers to a condition wherein the immune system attacks and destroys healthy cells, tissues, and organs of the body. In the longer run, it can also lead to abnormal growth of an organ and changes in organ function. Currently, more than 80 different autoimmune disorders have been identified by scientists, out of which Systemic Lupus Erythematosus (SLE), multiple sclerosis, rheumatoid arthritis, and type I diabetes, are the most common. Depending on the disorder, the doctor uses a combination of methods, which include a physical examination, medical history, blood tests, biopsy, and X-rays, to provide an effective diagnosis. They prescribe anti-inflammatory and immunosuppressant drugs, physical therapy, surgery, and injections, to control the overactive immune response and provide relief from symptoms.

Owing to the rising prevalence of autoimmune diseases, healthcare professionals around the world are focusing on the adoption of advanced technologies to conduct multiple tests with faster and more precise results. Apart from this, a large number of research and diagnostics institutes are undertaking public awareness campaigns to educate individuals about autoimmune diseases and their possible treatments and diagnosis, which is positively influencing the market growth. Furthermore, several governing authorities, along with non-governing organizations, are funding various programs to develop novel therapeutics. For instance, the AMP RA/SLE Program, launched by the Accelerating Medicines Partnership (AMP), is a public-private partnership between the National Institutes of Health (NIH), the US Food and Drug Administration (FDA) and multiple non-profit organizations. The program aims to identify relevant drug targets for the treatment of autoimmune diseases. Looking forward, IMARC Group expects the global autoimmune disease diagnosis market to grow at a CAGR of 8.10% during 2021-2026.

Breakup by Product Type:

  • Consumables and Assay Kits
  • Instruments

Breakup by Disease Type:

  • Systemic Autoimmune Disease
  • Rheumatoid Arthritis
  • Psoriasis
  • Systemic Lupus Erythematosus (SLE)
  • Multiple Sclerosis
  • Others
  • Localized Autoimmune Disease
  • Inflammatory Bowel Disease
  • Type 1 Diabetes
  • Thyroid
  • Others

Breakup by Test Type:

  • Routine Laboratory Tests
  • Inflammatory Markers
  • Autoantibodies and Immunologic Tests
  • Others

Breakup by End-User:

  • Clinical Laboratories
  • Hospitals
  • Others

Breakup by Region:

  • North America
  • United States
  • Canada
  • Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Australia
  • Indonesia
  • Others
  • Europe
  • Germany
  • France
  • United Kingdom
  • Italy
  • Spain
  • Russia
  • Others
  • Latin America
  • Brazil
  • Mexico
  • Others
  • Middle East and Africa

Competitive Landscape:

  • The report has also analysed the competitive landscape of the market with some of the key players being Abbott Laboratories, Aesku.Diagnostics GmbH & Co. KG, Beckman Coulter Inc. (Danaher Corporation), bioMerieux SA (Institut Merieux), Bio-Rad Laboratories Inc., Euroimmun AG (PerkinElmer Inc.), Hemagen Diagnostics Inc., Inova Diagnostics Inc. (Werfen Group S.A.), Myriad Genetics Inc., Quest Diagnostics Incorporated, Siemens Healthineers AG (Siemens AG), SQI Diagnostics, Thermo Fisher Scientific Inc., Trinity Biotech, etc.

Key Questions Answered in This Report:

  • How has the global autoimmune disease diagnosis market performed so far and how will it perform in the coming years?
  • What are the key regional markets?
  • What has been the impact of COVID-19 on the global autoimmune disease diagnosis market?
  • What is the breakup of the market based on the product type?
  • What is the breakup of the market based on the disease type?
  • What is the breakup of the market based on the test type?
  • What is the breakup of the market based on the end-user?
  • What are the various stages in the value chain of the industry?
  • What are the key driving factors and challenges in the industry?
  • What is the structure of the global autoimmune disease diagnosis market and who are the key players?
  • What is the degree of competition in the industry?
Table of Contents
Product Code: SR1020A08_Report

Table of Contents

1 Preface

2 Scope and Methodology

  • 2.1 Objectives of the Study
  • 2.2 Stakeholders
  • 2.3 Data Sources
    • 2.3.1 Primary Sources
    • 2.3.2 Secondary Sources
  • 2.4 Market Estimation
    • 2.4.1 Bottom-Up Approach
    • 2.4.2 Top-Down Approach
  • 2.5 Forecasting Methodology

3 Executive Summary

4 Introduction

  • 4.1 Overview
  • 4.2 Key Industry Trends

5 Global Autoimmune Disease Diagnosis Market

  • 5.1 Market Overview
  • 5.2 Market Performance
  • 5.3 Impact of COVID-19
  • 5.4 Market Forecast

6 Market Breakup by Product Type

  • 6.1 Consumables and Assay Kits
    • 6.1.1 Market Trends
    • 6.1.2 Market Forecast
  • 6.2 Instruments
    • 6.2.1 Market Trends
    • 6.2.2 Market Forecast

7 Market Breakup by Disease Type

  • 7.1 Systemic Autoimmune Disease
    • 7.1.1 Market Trends
    • 7.1.2 Market Breakup by Type
      • 7.1.2.1 Rheumatoid Arthritis
      • 7.1.2.2 Psoriasis
      • 7.1.2.3 Systemic Lupus Erythematosus (SLE)
      • 7.1.2.4 Multiple Sclerosis
      • 7.1.2.5 Others
    • 7.1.3 Market Forecast
  • 7.2 Localized Autoimmune Disease
    • 7.2.1 Market Trends
    • 7.2.2 Market Breakup by Type
      • 7.2.2.1 Inflammatory Bowel Disease
      • 7.2.2.2 Type 1 Diabetes
      • 7.2.2.3 Thyroid
      • 7.2.2.4 Others
    • 7.2.3 Market Forecast

8 Market Breakup by Test Type

  • 8.1 Routine Laboratory Tests
    • 8.1.1 Market Trends
    • 8.1.2 Market Forecast
  • 8.2 Inflammatory Markers
    • 8.2.1 Market Trends
    • 8.2.2 Market Forecast
  • 8.3 Autoantibodies and Immunologic Tests
    • 8.3.1 Market Trends
    • 8.3.2 Market Forecast
  • 8.4 Others
    • 8.4.1 Market Trends
    • 8.4.2 Market Forecast

9 Market Breakup by End-User

  • 9.1 Clinical Laboratories
    • 9.1.1 Market Trends
    • 9.1.2 Market Forecast
  • 9.2 Hospitals
    • 9.2.1 Market Trends
    • 9.2.2 Market Forecast
  • 9.3 Others
    • 9.3.1 Market Trends
    • 9.3.2 Market Forecast

10 Market Breakup by Region

  • 10.1 North America
    • 10.1.1 United States
      • 10.1.1.1 Market Trends
      • 10.1.1.2 Market Forecast
    • 10.1.2 Canada
      • 10.1.2.1 Market Trends
      • 10.1.2.2 Market Forecast
  • 10.2 Asia Pacific
    • 10.2.1 China
      • 10.2.1.1 Market Trends
      • 10.2.1.2 Market Forecast
    • 10.2.2 Japan
      • 10.2.2.1 Market Trends
      • 10.2.2.2 Market Forecast
    • 10.2.3 India
      • 10.2.3.1 Market Trends
      • 10.2.3.2 Market Forecast
    • 10.2.4 South Korea
      • 10.2.4.1 Market Trends
      • 10.2.4.2 Market Forecast
    • 10.2.5 Australia
      • 10.2.5.1 Market Trends
      • 10.2.5.2 Market Forecast
    • 10.2.6 Indonesia
      • 10.2.6.1 Market Trends
      • 10.2.6.2 Market Forecast
    • 10.2.7 Others
      • 10.2.7.1 Market Trends
      • 10.2.7.2 Market Forecast
  • 10.3 Europe
    • 10.3.1 Germany
      • 10.3.1.1 Market Trends
      • 10.3.1.2 Market Forecast
    • 10.3.2 France
      • 10.3.2.1 Market Trends
      • 10.3.2.2 Market Forecast
    • 10.3.3 United Kingdom
      • 10.3.3.1 Market Trends
      • 10.3.3.2 Market Forecast
    • 10.3.4 Italy
      • 10.3.4.1 Market Trends
      • 10.3.4.2 Market Forecast
    • 10.3.5 Spain
      • 10.3.5.1 Market Trends
      • 10.3.5.2 Market Forecast
    • 10.3.6 Russia
      • 10.3.6.1 Market Trends
      • 10.3.6.2 Market Forecast
    • 10.3.7 Others
      • 10.3.7.1 Market Trends
      • 10.3.7.2 Market Forecast
  • 10.4 Latin America
    • 10.4.1 Brazil
      • 10.4.1.1 Market Trends
      • 10.4.1.2 Market Forecast
    • 10.4.2 Mexico
      • 10.4.2.1 Market Trends
      • 10.4.2.2 Market Forecast
    • 10.4.3 Others
      • 10.4.3.1 Market Trends
      • 10.4.3.2 Market Forecast
  • 10.5 Middle East and Africa
    • 10.5.1 Market Trends
    • 10.5.2 Market Breakup by Country
    • 10.5.3 Market Forecast

11 SWOT Analysis

  • 11.1 Overview
  • 11.2 Strengths
  • 11.3 Weaknesses
  • 11.4 Opportunities
  • 11.5 Threats

12 Value Chain Analysis

13 Porters Five Forces Analysis

  • 13.1 Overview
  • 13.2 Bargaining Power of Buyers
  • 13.3 Bargaining Power of Suppliers
  • 13.4 Degree of Competition
  • 13.5 Threat of New Entrants
  • 13.6 Threat of Substitutes

14 Competitive Landscape

  • 14.1 Market Structure
  • 14.2 Key Players
  • 14.3 Profiles of Key Players
    • 14.3.1 Abbott Laboratories
      • 14.3.1.1 Company Overview
      • 14.3.1.2 Product Portfolio
      • 14.3.1.3 Financials
      • 14.3.1.4 SWOT Analysis
    • 14.3.2 Aesku.Diagnostics GmbH & Co. KG
      • 14.3.2.1 Company Overview
      • 14.3.2.2 Product Portfolio
    • 14.3.3 Beckman Coulter Inc. (Danaher Corporation)
      • 14.3.3.1 Company Overview
      • 14.3.3.2 Product Portfolio
      • 14.3.3.3 SWOT Analysis
    • 14.3.4 bioMerieux SA (Institut Merieux)
      • 14.3.4.1 Company Overview
      • 14.3.4.2 Product Portfolio
      • 14.3.4.3 Financials
      • 14.3.4.4 SWOT Analysis
    • 14.3.5 Bio-Rad Laboratories Inc.
      • 14.3.5.1 Company Overview
      • 14.3.5.2 Product Portfolio
      • 14.3.5.3 Financials
      • 14.3.5.4 SWOT Analysis
    • 14.3.6 Euroimmun AG (PerkinElmer Inc.)
      • 14.3.6.1 Company Overview
      • 14.3.6.2 Product Portfolio
      • 14.3.6.3 Financials
    • 14.3.7 Hemagen Diagnostics Inc.
      • 14.3.7.1 Company Overview
      • 14.3.7.2 Product Portfolio
    • 14.3.8 Inova Diagnostics Inc. (Werfen Group S.A.)
      • 14.3.8.1 Company Overview
      • 14.3.8.2 Product Portfolio
    • 14.3.9 Myriad Genetics Inc.
      • 14.3.9.1 Company Overview
      • 14.3.9.2 Product Portfolio
      • 14.3.9.3 Financials
      • 14.3.9.4 SWOT Analysis
    • 14.3.10 Quest Diagnostics Incorporated
      • 14.3.10.1 Company Overview
      • 14.3.10.2 Product Portfolio
      • 14.3.10.3 Financials
      • 14.3.10.4 SWOT Analysis
    • 14.3.11 Siemens Healthineers AG (Siemens AG)
      • 14.3.11.1 Company Overview
      • 14.3.11.2 Product Portfolio
      • 14.3.11.3 Financials
    • 14.3.12 SQI Diagnostics
      • 14.3.12.1 Company Overview
      • 14.3.12.2 Product Portfolio
      • 14.3.12.3 Financials
    • 14.3.13 Thermo Fisher Scientific Inc.
      • 14.3.13.1 Company Overview
      • 14.3.13.2 Product Portfolio
      • 14.3.13.3 Financials
      • 14.3.13.4 SWOT Analysis
    • 14.3.14 Trinity Biotech
      • 14.3.14.1 Company Overview
      • 14.3.14.2 Product Portfolio
      • 14.3.14.3 Financials
      • 14.3.14.4 SWOT Analysis

List of Figures

  • Figure 1: Global: Autoimmune Disease Diagnosis Market: Major Drivers and Challenges
  • Figure 2: Global: Autoimmune Disease Diagnosis Market: Sales Value (in Billion US$), 2015-2020
  • Figure 3: Global: Autoimmune Disease Diagnosis Market: Breakup by Product Type (in %), 2020
  • Figure 4: Global: Autoimmune Disease Diagnosis Market: Breakup by Disease Type (in %), 2020
  • Figure 5: Global: Autoimmune Disease Diagnosis Market: Breakup by Test Type (in %), 2020
  • Figure 6: Global: Autoimmune Disease Diagnosis Market: Breakup by End-User (in %), 2020
  • Figure 7: Global: Autoimmune Disease Diagnosis Market: Breakup by Region (in %), 2020
  • Figure 8: Global: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Billion US$), 2021-2026
  • Figure 9: Global: Autoimmune Disease Diagnosis (Consumables and Assay Kits) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 10: Global: Autoimmune Disease Diagnosis (Consumables and Assay Kits) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 11: Global: Autoimmune Disease Diagnosis (Instruments) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 12: Global: Autoimmune Disease Diagnosis (Instruments) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 13: Global: Autoimmune Disease Diagnosis (Systemic Autoimmune Disease) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 14: Global: Autoimmune Disease Diagnosis (Systemic Autoimmune Disease) Market: Breakup by Disease Type (in %), 2020
  • Figure 15: Global: Autoimmune Disease Diagnosis (Systemic Autoimmune Disease) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 16: Global: Autoimmune Disease Diagnosis (Localized Autoimmune Disease) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 17: Global: Autoimmune Disease Diagnosis (Localized Autoimmune Disease) Market: Breakup by Disease Type (in %), 2020
  • Figure 18: Global: Autoimmune Disease Diagnosis (Localized Autoimmune Disease) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 19: Global: Autoimmune Disease Diagnosis (Routine Laboratory Tests) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 20: Global: Autoimmune Disease Diagnosis (Routine Laboratory Tests) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 21: Global: Autoimmune Disease Diagnosis (Inflammatory Markers) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 22: Global: Autoimmune Disease Diagnosis (Inflammatory Markers) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 23: Global: Autoimmune Disease Diagnosis (Autoantibodies and Immunologic Tests) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 24: Global: Autoimmune Disease Diagnosis (Autoantibodies and Immunologic Tests) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 25: Global: Autoimmune Disease Diagnosis (Other Test Types) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 26: Global: Autoimmune Disease Diagnosis (Other Test Types) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 27: Global: Autoimmune Disease Diagnosis (Clinical Laboratories) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 28: Global: Autoimmune Disease Diagnosis (Clinical Laboratories) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 29: Global: Autoimmune Disease Diagnosis (Hospitals) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 30: Global: Autoimmune Disease Diagnosis (Hospitals) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 31: Global: Autoimmune Disease Diagnosis (Other End-Users) Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 32: Global: Autoimmune Disease Diagnosis (Other End-Users) Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 33: North America: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 34: North America: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 35: United States: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 36: United States: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 37: Canada: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 38: Canada: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 39: Asia Pacific: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 40: Asia Pacific: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 41: China: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 42: China: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 43: Japan: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 44: Japan: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 45: India: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 46: India: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 47: South Korea: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 48: South Korea: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 49: Australia: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 50: Australia: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 51: Indonesia: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 52: Indonesia: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 53: Others: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 54: Others: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 55: Europe: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 56: Europe: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 57: Germany: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 58: Germany: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 59: France: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 60: France: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 61: United Kingdom: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 62: United Kingdom: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 63: Italy: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 64: Italy: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 65: Spain: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 66: Spain: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 67: Russia: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 68: Russia: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 69: Others: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 70: Others: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 71: Latin America: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 72: Latin America: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 73: Brazil: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 74: Brazil: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 75: Mexico: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 76: Mexico: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 77: Others: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 78: Others: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 79: Middle East and Africa: Autoimmune Disease Diagnosis Market: Sales Value (in Million US$), 2015 & 2020
  • Figure 80: Middle East and Africa: Autoimmune Disease Diagnosis Market Forecast: Sales Value (in Million US$), 2021-2026
  • Figure 81: Global: Autoimmune Disease Diagnosis Industry: SWOT Analysis
  • Figure 82: Global: Autoimmune Disease Diagnosis Industry: Value Chain Analysis
  • Figure 83: Global: Autoimmune Disease Diagnosis Industry: Porter's Five Forces Analysis

List of Tables

  • Table 1: Global: Autoimmune Disease Diagnosis Market: Key Industry Highlights, 2020 and 2026
  • Table 2: Global: Autoimmune Disease Diagnosis Market Forecast: Breakup by Product Type (in Million US$), 2021-2026
  • Table 3: Global: Autoimmune Disease Diagnosis Market Forecast: Breakup by Disease Type (in Million US$), 2021-2026
  • Table 4: Global: Autoimmune Disease Diagnosis Market Forecast: Breakup by Test Type (in Million US$), 2021-2026
  • Table 5: Global: Autoimmune Disease Diagnosis Market Forecast: Breakup by End-User (in Million US$), 2021-2026
  • Table 6: Global: Autoimmune Disease Diagnosis Market Forecast: Breakup by Region (in Million US$), 2021-2026
  • Table 7: Global: Autoimmune Disease Diagnosis Market Structure
  • Table 8: Global: Autoimmune Disease Diagnosis Market: Key Players
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