PUBLISHER: MarketsandMarkets | PRODUCT CODE: 2101307
PUBLISHER: MarketsandMarkets | PRODUCT CODE: 2101307
The single-use bioreactors market is projected to reach USD 9.58 billion by 2031 from an estimated USD 5.43 billion in 2026, at a CAGR of 12.0% during the forecast period of 2026 to 2031. Market growth is primarily supported by expanding biologics and biosimilar production, rising vaccine manufacturing, increasing outsourcing to CDMOs, and greater adoption of flexible bioprocessing technologies.
| Scope of the Report | |
|---|---|
| Years Considered for the Study | 2026-2031 |
| Base Year | 2025 |
| Forecast Period | 2026-2031 |
| Units Considered | Value (USD billion) |
| Segments | Product, Type, Cell Type, Process Mode, Molecule Type, Application, End User |
| Regions covered | North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa |
The growing use of single-use systems in monoclonal antibody, recombinant protein, viral vector, and cell & gene therapy manufacturing is further accelerating demand. Their lower capital requirements, reduced cleaning validation, faster product changeovers, and suitability for multiproduct facilities are expected to support market expansion.

By application, the bioproduction segment accounted for the largest share of the market in 2025.
In 2025, the bioproduction segment accounted for the largest share of the global single-use bioreactors market. These systems are extensively used for the commercial and clinical production of monoclonal antibodies, vaccines, recombinant proteins, biosimilars, viral vectors, and other biologics. The segment's leading position is supported by increasing demand for biologics, expansion of global manufacturing capacity, and growing adoption of scalable single-use platforms across pharmaceutical and biotechnology companies and CDMOs. Their ability to reduce contamination risks, shorten turnaround times, and support batch, fed-batch, and perfusion processes further strengthens their use in bioproduction applications.
The monoclonal antibodies segment accounted for a major share of the single-use bioreactors market in 2025.
The single-use bioreactors market is categorized by molecule type into monoclonal antibodies, vaccines, cell & gene therapy, and therapeutic proteins & peptides. The monoclonal antibodies segment accounted for the largest market share in 2025, supported by the substantial number of approved products, extensive development pipelines, and continued expansion of commercial manufacturing capacity. Monoclonal antibody production requires scalable and tightly controlled mammalian cell culture processes, creating sustained demand for stirred-tank single-use bioreactors, bags, assemblies, sensors, and fluid-management components. Their suitability for batch, fed-batch, and intensified processing further supports adoption across pharmaceutical and biotechnology companies and CDMOs.
The Asia Pacific region is expected to experience the highest CAGR in the single-use bioreactors market from 2026 to 2031.
The single-use bioreactors market is divided into North America, Europe, Asia Pacific, Latin America, the Middle East, and Africa. Asia Pacific is expected to register the fastest growth during the forecast period, driven by expanding biologics and biosimilar production, increasing vaccine manufacturing, rising CDMO capacity, and greater investment in domestic biopharmaceutical infrastructure. China, India, Japan, South Korea, and Australia are strengthening their upstream processing capabilities through new facilities, capacity additions, and wider adoption of modular and flexible production technologies. Government support for local manufacturing and the growth of cell & gene therapy activity are further accelerating regional demand.
Sartorius AG (Germany), Danaher Corporation (US), Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany), Avantor, Inc. (US), Repligen Corporation (US), Getinge AB (Sweden), Eppendorf SE (Germany), Parker Hannifin Corporation (US), Entegris (US), Saint-Gobain (France), Corning Incorporated (US), Lonza (Switzerland), TECNIC Process Equipment Manufacturing, S.L. (Spain), ZACROS Corporation (Japan), Adolf Kuhner AG (Switzerland), OmniBRx Biotechnologies Pvt Ltd. (India), New Horizon Biotechnology, Inc. (US), PBS Biotech, Inc. (US), bbi-biotech GmbH (Germany), ABEC, Inc. (US), Esco Lifesciences Group (US), Distek, Inc. (US), SATAKE MultiMix Corporation (Japan), Cell Culture Company, LLC (US), MicroDigital Co., Ltd. (South Korea), BIONET (Spain), Meissner Filtration Products, Inc. (US), Solida Biotech GmbH (Germany), G&G Technologies, Inc. (US), PharmNXT Biotech (India), and Tofflon Life Science Co., Ltd. (China) are some of the key companies offering single-use bioreactors solutions.
Research Coverage
This research report categorizes the single-use bioreactors market by product (single-use bioreactor systems, single-use bags, single-use assemblies, and other products), type (stirred-tank single-use bioreactors, wave-induced single-use bioreactors, fixed-bed single-use bioreactors, bubble-column single-use bioreactors, and other single-use bioreactors), cell type (mammalian cells, bacterial cells, yeast cells, and other cells), molecule type (monoclonal antibodies, vaccines, cell & gene therapy, and therapeutic proteins & peptides), process mode (fed-batch, batch, and perfusion/continuous), application (bioproduction, process development, and research & development), end user (pharmaceutical and biotechnology companies, CROs & CMOs, and academic & research institutes), and region (North America, Europe, Asia Pacific, Latin America, Middle East, and Africa).
The scope of the report provides detailed information on major factors such as drivers, challenges, opportunities, and restraints that influence the growth of the single-use bioreactors market. A comprehensive analysis of key industry players has been conducted to provide insights into their business overviews, product portfolios, and key strategies, including collaborations, partnerships, expansions, agreements, acquisitions, and recent developments in the single-use bioreactors market.
Key Benefits of Buying the Report
This report offers a comprehensive overview of the single-use bioreactors market. It aims to assess the market size and future growth opportunities across various segments. The report also features an in-depth competitive analysis of the major market players, including their company profiles, recent developments, and key market strategies