U.S. Phosphoramidite Market Size, Share, Trends, & Industry Analysis Report By Type (DNA Phosphoramidites, RNA Phosphoramidites), By Application, By End User, and By Country

Description

List of Tables

The US Phosphoramidites Market size is expected to reach USD 843.12 Million by 2034, according to a new study by Polaris Market Research. The report "U.S. Phosphoramidite Market Share, Size, Trends, Industry Analysis Report: By Type (DNA Phosphoramidites, RNA Phosphoramidites), By Application, By End User, and By Country; Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.

The demand for phosphoramidites in the U.S. is growing due to their extensive use in therapeutic research, molecular diagnostics, gene editing, and synthetic biology. High-purity DNA and RNA phosphoramidites support oligonucleotide synthesis, enabling cost-effective drug development and precision medicine applications.

Market growth is driven by increasing adoption of customized phosphoramidite derivatives, high-throughput automated synthesis platforms, and a rising focus on RNA therapeutics and CRISPR-based research. Technological advancements in reagent stability, yield optimization, and digital process integration help manufacturers meet diverse R&D requirements while ensuring regulatory compliance.

U.S. Phosphoramidite Market Report Highlights

Based on type, the DNA phosphoramidites segment dominated the market in 2024 due to widespread use in therapeutic research, RNA interference, and molecular diagnostics.

Based on application, drug discovery and development held the largest share in 2024, driven by its extensive use in preclinical and clinical research pipelines.

In terms of end users, pharmaceutical and biotechnology companies dominated the market in 2024, while academic and research institutes are projected to grow at the fastest rate.

A few global key market players include Glen Research, TriLink BioTechnologies, Thermo Fisher Scientific, ChemGenes Corp., Biosynth Carbosynth, BOC Sciences, emp BIOTECH, Lumiprobe, Hunan Honya Biotech Co., Ltd., GenScript, Integrated DNA Technologies, Inc., and Merck KGaA.

Polaris Market Research has segmented the market report on the basis of type, application, end user, and country:

By Type Outlook (Revenue, USD Million, 2020-2034)

DNA Phosphoramidites

RNA Phosphoramidites

Labeled Phosphoramidites

Modifier Phosphoramidites

Other Types

By Application Outlook (Revenue, USD Million, 2020-2034)

Drug Discovery & Development

Diagnostics Development

Gene Editing & Synthetic Biology

Other Applications

By End User Outlook (Revenue, USD Million, 2020-2034)

Pharmaceutical and Biotechnology Companies

Academic and Research Institutes

Other End Users

Product Code: PM6271

1. Introduction

1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
1.2. Stakeholders

2. Executive Summary

2.1. Market Highlights

3. Research Methodology

3.1. Overview
- 3.1.1. Data Mining
3.2. Data Sources
- 3.2.1. Primary Sources
- 3.2.2. Secondary Sources

4. U.S. Phosphoramidite Market Insights

4.1. U.S. Phosphoramidite Market - Market Snapshot
4.2. U.S. Phosphoramidite Market Dynamics
- 4.2.1. Drivers and Opportunities
  - 4.2.1.1. Expansion of the Biotechnology and Pharmaceutical Sectors in the U.S.
  - 4.2.1.2. Increasing Focus on Personalized Medicine and Precision Healthcare
- 4.2.2. Restraints and Challenges
  - 4.2.2.1. High Production Costs and Complex Manufacturing Processes
4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
4.4. PESTEL Analysis
4.5. U.S. Phosphoramidite Market Trends
4.6. Value Chain Analysis

5. U.S. Phosphoramidite Market, by Type

5.1. Key Findings
5.2. Introduction
- 5.2.1. U.S. Phosphoramidite Market, by Type, 2020-2034 (USD Million)
5.3. DNA Phosphoramidites
- 5.3.1. Global Phosphoramidite Market, by DNA Phosphoramidites, by Region, 2020-2034 (USD Million)
5.4. RNA Phosphoramidites
- 5.4.1. Global Phosphoramidite Market, by RNA Phosphoramidites, by Region, 2020-2034 (USD Million)
5.5. Labeled Phosphoramidites
- 5.5.1. Global Phosphoramidite Market, by Labeled Phosphoramidites, by Region, 2020-2034 (USD Million)
5.6. Modifier Phosphoramidites
- 5.6.1. Global Phosphoramidite Market, by Modifier Phosphoramidites, by Region, 2020-2034 (USD Million)
5.7. Other Types
- 5.7.1. Global Phosphoramidite Market, by Other Types, by Region, 2020-2034 (USD Million)

6. U.S. Phosphoramidite Market, by Application

6.1. Key Findings
6.2. Introduction
- 6.2.1. U.S. Phosphoramidite Market, by Application, 2020-2034 (USD Million)
6.3. Drug Discovery & Development
- 6.3.1. Global Phosphoramidite Market, by Drug Discovery & Development, by Region, 2020-2034 (USD Million)
6.4. Diagnostics Development
- 6.4.1. Global Phosphoramidite Market, by Diagnostics Development, by Region, 2020-2034 (USD Million)
6.5. Gene Editing & Synthetic Biology
- 6.5.1. Global Phosphoramidite Market, by Gene Editing & Synthetic Biology, by Region, 2020-2034 (USD Million)
6.6. Other Applications
- 6.6.1. Global Phosphoramidite Market, by Other Applications, by Region, 2020-2034 (USD Million)

7. U.S. Phosphoramidite Market, by End User

7.1. Key Findings
7.2. Introduction
- 7.2.1. U.S. Phosphoramidite Market, by Application, 2020-2034 (USD Million)
7.3. Pharmaceutical and Biotechnology Companies
- 7.3.1. Global Phosphoramidite Market, by Pharmaceutical and Biotechnology Companies, by Region, 2020-2034 (USD Million)
7.4. Academic and Research Institutes
- 7.4.1. Global Phosphoramidite Market, by Academic and Research Institutes, by Region, 2020-2034 (USD Million)
7.5. Other End Users
- 7.5.1. Global Phosphoramidite Market, by Other End Users, by Region, 2020-2034 (USD Million)

8. U.S. Phosphoramidite Market, by Country

8.1. Key Findings
8.2. Introduction
- 8.2.1. U.S. Phosphoramidite Market Assessment, By Country, 2020-2034 (USD Million)
- 8.2.2. U.S. Phosphoramidite Market
  - 8.2.2.1. U.S.: Phosphoramidite Market, by Type, 2020-2034 (USD Million)
  - 8.2.2.2. U.S.: Phosphoramidite Market, by Application, 2020-2034 (USD Million)
  - 8.2.2.3. U.S.: Phosphoramidite Market, by End User, 2020-2034 (USD Million)

9. Competitive Landscape

9.1. Expansion and Acquisition Analysis
- 9.1.1. Expansion
- 9.1.2. Acquisitions
9.2. Partnerships/Collaborations/Agreements/Exhibitions

10. Company Profiles

10.1. Biosynth Carbosynth
- 10.1.1. Company Overview
- 10.1.2. Financial Performance
- 10.1.3. Product Benchmarking
- 10.1.4. Recent Development
10.2. BOC Sciences
- 10.2.1. Company Overview
- 10.2.2. Financial Performance
- 10.2.3. Product Benchmarking
- 10.2.4. Recent Development
10.3. ChemGenes Corp.
- 10.3.1. Company Overview
- 10.3.2. Financial Performance
- 10.3.3. Product Benchmarking
- 10.3.4. Recent Development
10.4. emp BIOTECH
- 10.4.1. Company Overview
- 10.4.2. Financial Performance
- 10.4.3. Product Benchmarking
- 10.4.4. Recent Development
10.5. GenScript
- 10.5.1. Company Overview
- 10.5.2. Financial Performance
- 10.5.3. Product Benchmarking
- 10.5.4. Recent Development
10.6. Glen Research
- 10.6.1. Company Overview
- 10.6.2. Financial Performance
- 10.6.3. Product Benchmarking
- 10.6.4. Recent Development
10.7. Hunan Honya Biotech Co., Ltd.
- 10.7.1. Company Overview
- 10.7.2. Financial Performance
- 10.7.3. Product Benchmarking
- 10.7.4. Recent Development
10.8. Integrated DNA Technologies, Inc.
- 10.8.1. Company Overview
- 10.8.2. Financial Performance
- 10.8.3. Product Benchmarking
- 10.8.4. Recent Development
10.9. Lumiprobe
- 10.9.1. Company Overview
- 10.9.2. Financial Performance
- 10.9.3. Product Benchmarking
- 10.9.4. Recent Development
10.10. Merck KGaA
- 10.10.1. Company Overview
- 10.10.2. Financial Performance
- 10.10.3. Product Benchmarking
- 10.10.4. Recent Development
10.11. Thermo Fisher Scientific
- 10.11.1. Company Overview
- 10.11.2. Financial Performance
- 10.11.3. Product Benchmarking
- 10.11.4. Recent Development
10.12. TriLink BioTechnologies
- 10.12.1. Company Overview
- 10.12.2. Financial Performance
- 10.12.3. Product Benchmarking
- 10.12.4. Recent Development