PUBLISHER: Roots Analysis | PRODUCT CODE: 1830065
PUBLISHER: Roots Analysis | PRODUCT CODE: 1830065
As per Roots Analysis, the buffer preparation market size is currently valued at USD 8.58 billion and is projected to reach 17.96 billion by 2035, growing at a CAGR of 7.8% during the forecast period.
The market sizing and opportunity analysis has been segmented across the following parameters:
Scale of Operation
Type of System Component
Type of Buffer Formulation
Type of Molecule
Type of Compatible Biologic
Type of Buffer Packaging
Geographical Regions
Buffer Manufacturing Market: Growth and Trends
Buffers are water-based solutions utilized to regulate pH during the drug production process and are essential for preserving the stability of both small molecules and biologics. Additionally, buffers play a role in numerous upstream and downstream bioprocesses for different purposes, including improving the yield of target products, ensuring consistent purification conditions, and stabilizing the end product while preserving its functional properties.
Traditional pharmaceutical buffer production face numerous challenges that affect their manufacturing processes, leading to elevated production expenses and inconsistencies between batches of final products. Thus, the incorporation of an innovative buffer production system in their manufacturing plants is necessary, owing to intricate processes and limited resources or the need to contract pharmaceutical buffer production to external service providers. Moreover, outsourcing the production of pharmaceutical buffers minimizes the requirement for large facilities and significant capital investment, while also simplifying the intricate logistics associated with buffer production and storage. In the past few years, the production of buffers and buffer management systems has quickly become popular. These systems actively incorporate cutting-edge technologies to preserve the physiological conditions of buffers throughout downstream processes. Additionally, the increasing need for buffers and the difficulties related to conventional buffer production are expected to propel market expansion in buffer manufacturing in the years to come.
Buffer Preparation Market: Key Insights
The report delves into the current state of the buffer preparation market and identifies potential growth opportunities within the industry. Some key findings from the report include:
Buffer Preparation Market: Key Segments
Commercial Scale Holds the Largest Share in the Overall Buffer Preparation Market
The global market is segmented across different scales of operation, such as preclinical / clinical and commercial. Within the buffer manufacturing systems market in the current year, the commercial scale segment is likely to capture the maximum share (~85%) and this trend is likely to remain the same in the coming years. This results from the expanding pipeline of biopharmaceutical products, significant investment in research and development, and technological developments, which creates a demand for advanced buffer preparation solutions in pharmaceutical production.
Reusable Buffer Mixing / Preparation Equipment Leads the Buffer Preparation Market
Based on types of system components, the global buffer manufacturing system market size is segmented across single-use buffer mixing / preparation equipment and reusable buffer mixing / preparation equipment. Our estimates suggest that the reusable buffer mixing / preparation equipment market segment is likely to capture the majority share (~80%) in the overall market in the current year and is likely to grow at a relatively faster rate during the forecast period.
Liquid Formulation Captures the Largest Share
This segment highlights the distribution of the global services market across different buffer formulations, such as liquid formulations and powder formulations. Currently, the liquid formulations segment is likely to capture the maximum share (~70%); further, this trend is likely to remain the same in the future as well. This is due to liquid buffers providing consistency between batches and ultimately minimizing the chance of human mistakes in buffer production.
Small Molecules Holds the Largest Share in the Current Year
This segment highlights the distribution of the global services market across different types of molecules, such as small molecules and biologics. Currently, the small molecules segment is likely to capture the maximum share (~75%); further, this trend is likely to remain the same in the future as well. This is due to the extensive therapeutic potential of small molecules and the rising occurrence of chronic illnesses, which is boosting the demand for greater drug production, consequently heightening the need for buffers in manufacturing.
Currently, Antibodies Segment Captures Majority of the Buffer Preparation Market Share
This segment highlights the distribution of the global buffer manufacturing services market across different types of compatible biologics, such as antibodies, vaccines, proteins / peptides, cell and gene therapies and other biologics. In the current year, the antibodies segment is likely to capture the maximum share (~55%) of the overall market; further, this trend is likely to remain the same in the future as well. The cell and gene therapies segment will grow at a significantly higher CAGR (19.5%) throughout the forecast period.
Bottles Segment Captures the Majority of the Market Share
The global services market is segmented into different types of packaging formats, such as bottles, bags, bioprocess containers, drums and other packaging. The bottles segment captures the majority share (~40%) in the overall market in the current year and is likely to dominate the market in the future as well.
North America is Likely to Capture the Majority Share
This segment highlights the distribution of the buffer manufacturing industry size across various geographies, namely North America, Europe, Asia-Pacific, Middle East and North Africa and Latin America. According to our projections, North America is likely to capture the majority share (~40%) in the overall market currently, and this trend is unlikely to change in the future. It is important to note that companies based in North America are progressively implementing buffer production systems to lower manufacturing expenses, enhance efficiency, and ensure high-quality batch products. Additionally, the companies provide tailored buffer preparation services for research laboratories and industries. Further, the market in Asia-Pacific is likely to grow at a high CAGR (8%), during the forecast period.
Buffer preparation market: Research Coverage
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