PUBLISHER: The Business Research Company | PRODUCT CODE: 1760476
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760476
Autoimmune monoclonal antibodies are laboratory-created proteins designed to target specific components of the immune system involved in autoimmune diseases. These antibodies help regulate or block abnormal immune responses that mistakenly attack the body's own tissues. Their primary purpose is to reduce inflammation and prevent the immune system from attacking healthy tissues, thereby minimizing damage and maintaining normal physiological function.
The main types of autoimmune monoclonal antibodies include Immunoglobulin G (IgG) monoclonal antibodies, Immunoglobulin M (IgM) monoclonal antibodies, chimeric monoclonal antibodies, and fully human monoclonal antibodies. IgG monoclonal antibodies are lab-engineered proteins that specifically target and bind to molecules in the body, regulating immune responses to provide precise and prolonged therapeutic effects in autoimmune treatments. These antibodies can be administered through various routes, including subcutaneous, intravenous, and intramuscular. They are used to treat conditions such as rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, psoriasis, and inflammatory bowel disease. Distribution channels for these antibodies include hospital pharmacies, online pharmacies, and retail pharmacies. The primary end-users of these therapies include hospitals, outpatient clinics, homecare settings, and research institutions.
The autoimmune monoclonal antibody market research report is one of a series of new reports from The Business Research Company that provides autoimmune monoclonal antibody market statistics, including the autoimmune monoclonal antibody industry global market size, regional shares, competitors with the autoimmune monoclonal antibody market share, detailed autoimmune monoclonal antibody market segments, market trends, and opportunities, and any further data you may need to thrive in the autoimmune monoclonal antibody industry. This autoimmune monoclonal antibody market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The autoimmune monoclonal antibody market size has grown strongly in recent years. It will grow from $65.83 billion in 2024 to $71.71 billion in 2025 at a compound annual growth rate (CAGR) of 8.7%. The growth during the historic period can be attributed to several factors, including the increasing prevalence of autoimmune diseases, the growing use of biologics in treatment, rising awareness of targeted therapies, early approvals of monoclonal antibody drugs, and the expansion of healthcare access in developed countries.
The autoimmune monoclonal antibody market size is expected to see strong growth in the next few years. It will grow to $98.81 billion in 2029 at a compound annual growth rate (CAGR) of 8.4%. The growth during the forecast period can be attributed to several factors, including the increasing demand for personalized medicine, rising adoption of biosimilars, expansion of clinical trials in autoimmune therapy, a growing geriatric population, and the rising prevalence of chronic immune disorders. Key trends during this period include advancements in antibody engineering, the development of bispecific antibodies, the growing use of artificial intelligence in drug discovery, the integration of genomics in treatment planning, and the emergence of novel drug delivery systems.
The growing demand for biologics is expected to drive the expansion of the autoimmune monoclonal antibody market in the coming years. Biologics refer to medical products derived from living organisms or their components, used for the treatment, prevention, or diagnosis of diseases. The increasing demand for biologics is largely due to their ability to effectively treat complex conditions such as cancer, autoimmune disorders, and genetic diseases, where traditional therapies may not be as effective. Autoimmune monoclonal antibodies enhance biologic treatments by providing targeted immune modulation, making them effective in managing overactive immune responses. These therapies reduce the reliance on broad immunosuppressants by offering precise treatment, improving patient outcomes, and minimizing side effects. For example, in June 2024, Cardinal Health Inc., a US-based healthcare company, reported that there were 40 FDA-approved biosimilar products in 2023, 25 of which were commercially available in the US market, an increase from 33 biosimilar products in 2022. Therefore, the rising demand for biologics is driving the growth of the autoimmune monoclonal antibody market.
Leading companies in the autoimmune monoclonal antibody market are focusing on developing innovative solutions, such as biosimilars, to enhance safety, efficacy, and quality. Biosimilar development involves creating biological products that are highly similar to existing approved biologics, ensuring safety, efficacy, and quality through advanced biotechnology, rigorous testing, and clinical studies. For example, in February 2025, Biocon Biologics Limited, an India-based biopharmaceutical company, launched YESINTEK, a biosimilar designed to treat autoimmune diseases such as Crohn's disease, ulcerative colitis, and psoriasis. YESINTEK targets and inhibits the activity of interleukin-12 and interleukin-23 to reduce inflammation and regulate immune responses. By mimicking the reference product Stelara, YESINTEK helps manage long-term disease while improving patient access to biologic therapies.
In June 2023, Merck & Co., a US-based pharmaceutical company, acquired Prometheus Biosciences, Inc. for approximately $10.8 billion. This acquisition allows Merck to accelerate the development of precision medicine in immunology by utilizing Prometheus' technology, data analytics, and the TL1A-targeting candidate PRA023 to address unmet needs in immune-mediated diseases. Prometheus Biosciences, Inc. is a US-based biotechnology company specializing in providing autoimmune monoclonal antibodies.
Major players in the autoimmune monoclonal antibody market are Johnson & Johnson, F. Hoffmann-La Roche Ltd, Pfizer Inc., Merck & Co. Inc., AbbVie Inc., Novartis AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Eli Lilly and Company, Amgen Inc., Teva Pharmaceutical Industries Ltd., Regeneron Pharmaceuticals Inc., UCB S.A., Genmab A/S, Zymeworks Inc., Xencor Inc., Immutep Limited, Cue Biopharma Inc., Santa Ana Bio Inc.
North America was the largest region in the autoimmune monoclonal antibody market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in autoimmune monoclonal antibody report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the autoimmune monoclonal antibody market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The autoimmune monoclonal antibody market consists of sales of adalimumab (humira), etanercept (enbrel), infliximab (remicade), rituximab (rituxan), tocilizumab (actemra), belimumab (benlysta), and secukinumab (cosentyx). Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Autoimmune Monoclonal Antibody Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on autoimmune monoclonal antibody market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for autoimmune monoclonal antibody ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The autoimmune monoclonal antibody market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.