PUBLISHER: The Business Research Company | PRODUCT CODE: 1760649
PUBLISHER: The Business Research Company | PRODUCT CODE: 1760649
Next-generation antibody drugs are advanced therapeutic antibodies developed to target specific antigens with greater precision and efficacy, often incorporating innovative technologies such as bispecific antibodies or antibody-drug conjugates. These drugs aim to enhance disease treatment outcomes by improving targeting abilities and reducing side effects.
The main product types of next-generation antibody drugs include monoclonal antibodies, bispecific antibodies, antibody-drug conjugates, and others. Monoclonal antibodies are identical copies of a single antibody, created by cloning a unique immune cell, and are used to treat various conditions such as cancer and autoimmune disorders. Their mechanisms of action include checkpoint inhibitors, immune modulators, receptor blockers, targeted cytotoxic agents, and neutralizing antibodies. Delivery methods for these drugs include intravenous (IV), subcutaneous, intramuscular administration, oral formulations, and transdermal delivery systems. They are applied in oncology, autoimmune diseases, infectious diseases, and other areas, and are used by hospitals, research institutes, specialty clinics, and other healthcare providers.
The next generation antibody drug market research report is one of a series of new reports from The Business Research Company that provides next generation antibody drug market statistics, including the next generation antibody drug industry's global market size, regional shares, competitors with the next generation antibody drug market share, detailed next-generation antibody drug market segments, market trends and opportunities, and any further data you may need to thrive in the next generation antibody drug market. This next generation antibody drug market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The next generation antibody drug market size has grown rapidly in recent years. It will grow from $14.26 billion in 2024 to $16.54 billion in 2025 at a compound annual growth rate (CAGR) of 16.0%. The growth during the historic period can be attributed to the increasing demand for targeted therapies, rising cancer prevalence, growing adoption of immuno-oncology therapies, heightened focus on autoimmune diseases, and expanding regulatory support.
The next generation antibody drug market size is expected to see rapid growth in the next few years. It will grow to $29.72 billion in 2029 at a compound annual growth rate (CAGR) of 15.8%. The growth in the forecast period is expected to be driven by rising demand for personalized medicine, expanding drug pipelines, increasing healthcare awareness, more research collaborations, and a growing aging population. Major trends in the forecast period include advancements in antibody-drug conjugates, technological progress in bispecific antibodies, integration of next-generation sequencing, developments in protein engineering, and advancements in gene therapy integration.
The growing emphasis on personalized medicine is anticipated to drive the expansion of the next-generation antibody-drug market. Personalized medicine tailors healthcare and treatment approaches to individual patients, considering their genetic, environmental, and lifestyle factors to provide more effective and targeted therapies. This shift toward personalized medicine is fueled by advancements in genomic sequencing, which allow for more accurate diagnoses and customized treatment plans. Next-generation antibody drugs support this trend by enabling the development of therapies tailored to a patient's unique genetic makeup and disease characteristics, enhancing efficacy and reducing side effects. For example, in February 2024, the Personalized Medicine Coalition, a U.S.-based organization promoting personalized medicine, reported that in 2023, the U.S. Food and Drug Administration (FDA) approved 16 new personalized treatments for rare diseases, up from 6 in 2022. Thus, the growing emphasis on personalized medicine is driving the next-generation antibody drug market.
Companies in the next-generation antibody drug market are focusing on developing innovative solutions, such as antibody-drug conjugates (ADCs), to improve targeted cancer therapies, enhance treatment efficacy, and minimize systemic toxicity. ADCs combine a monoclonal antibody with a cytotoxic drug via a linker, allowing the drug to specifically target tumor cells while sparing healthy tissue. For instance, in January 2024, BioNTech SE, a Germany-based biotechnology firm, partnered with Duality Biologics (Suzhou) Co. Ltd., a Chinese pharmaceutical company, to receive a Fast Track designation from the U.S. FDA for their ADC candidate, BNT325/DB-1305, intended to treat platinum-resistant ovarian cancer. This drug utilizes DualityBio's DITAC (Duality Immune Toxin Antibody Conjugates) platform, which pairs a highly potent cytotoxic payload with a monoclonal antibody, ensuring precise delivery to cancer cells. The ability of BNT325/DB-1305 to selectively target cancer cells while minimizing harm to healthy tissue is a key advantage in enhancing treatment outcomes and reducing side effects.
In March 2024, Johnson & Johnson, a U.S.-based pharmaceutical company, acquired Ambrx Biopharma for an undisclosed sum. Through this acquisition, Johnson & Johnson aims to enhance its oncology portfolio by developing advanced, targeted antibody-drug conjugates that improve outcomes and minimize side effects for patients with hard-to-treat cancers. Ambrx Biopharma is dedicated to advancing the development of next-generation antibody-drug conjugates.
Major players in the next generation antibody drug market are Actinium Pharmaceuticals Inc., Pfizer Inc., F. Hoffmann-La Roche Ltd., Bristol-Myers Squibb Company, AstraZeneca plc, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Gilead Sciences Inc., Amgen Inc., Boehringer Ingelheim International GmbH, Regeneron Pharmaceuticals Inc., Biogen Inc., Kyowa Hakko Kirin Co. Ltd., Samsung Biologics Co. Ltd., WuXi Biologics Inc., Akeso Inc., Xencor Inc., ImmunoGen Inc., Philogen S.p.A., Telix Pharmaceuticals Limited.
North America was the largest region in the next generation antibody drug market in 2024. The regions covered in next generation antibody drug report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the next generation antibody drug market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The next generation antibody drug market consists of sales of engineered monoclonal antibodies, antibody-drug conjugates (ADCs), bispecific antibodies, and related biologic therapies. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Next Generation Antibody Drug Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on next generation antibody drug market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for next generation antibody drug ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The next generation antibody drug market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.