PUBLISHER: The Business Research Company | PRODUCT CODE: 1889612
PUBLISHER: The Business Research Company | PRODUCT CODE: 1889612
Viral vector purification is the procedure of separating viral vectors from production-related impurities, including host cell proteins, DNA, and other contaminants, to obtain a highly pure and safe final product. Its main goal is to ensure that viral vectors are appropriate for therapeutic use, maintaining their effectiveness and safety in gene therapy applications.
The primary vector types involved in viral vector purification include adenoviral vectors, lentiviral vectors, adeno-associated viral vectors, retroviral vectors, and others. Adenoviral vectors are viruses engineered to deliver genetic material into cells and are widely used in gene therapy and vaccine development. The process encompasses product types such as kits, reagents, instruments, and services, employing purification methods like chromatography, ultrafiltration, precipitation, and more. These techniques support applications in gene therapy, vaccinology, research, and other fields, serving end users including pharmaceutical and biotechnology companies, academic and research institutions, contract research organizations, and others.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the healthcare sector, particularly in the supply of critical medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are facing higher costs for imported surgical instruments, imaging equipment, and consumables such as syringes and catheters, many of which have limited domestic alternatives. These increased costs are straining healthcare budgets, leading some providers to delay equipment upgrades or pass on expenses to patients. Additionally, tariffs on raw materials and components are disrupting the production of essential drugs and devices, causing supply chain bottlenecks. In response, the industry is diversifying sourcing strategies, boosting local manufacturing where possible, and advocating for tariff exemptions on life-saving medical products.
The viral vector purification market research report is one of a series of new reports from The Business Research Company that provides viral vector purification market statistics, including the viral vector purification industry global market size, regional shares, competitors with the viral vector purification market share, detailed viral vector purification market segments, market trends, and opportunities, and any further data you may need to thrive in the viral vector purification industry. This viral vector purification market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The viral vector purification market size has grown rapidly in recent years. It will grow from $1.48 billion in 2024 to $1.75 billion in 2025 at a compound annual growth rate (CAGR) of 18.3%. Growth during the historic period can be linked to expanding biopharmaceutical production capacity, increased use of viral vectors in research, rising government funding for biotechnology initiatives, the growth of contract manufacturing organizations, and strengthening collaborations between academia and industry.
The viral vector purification market size is expected to see rapid growth in the next few years. It will grow to $3.38 billion in 2029 at a compound annual growth rate (CAGR) of 17.9%. Growth in the forecast period can be attributed to rising investment in advanced purification technologies, a heightened focus on scalable manufacturing solutions, continued expansion of gene delivery platforms, broader adoption of viral vectors in emerging markets, and growing demand for efficient downstream processing. Key trends anticipated in the forecast period include the development of new purification methods, innovations in single-use bioprocessing systems, advancements in continuous purification workflows, the emergence of hybrid chromatography approaches, and progress in automated process monitoring technologies.
The growing demand for gene therapies is expected to drive the expansion of the viral vector purification market in the coming years. Gene therapies are medical treatments that involve the introduction, removal, or modification of genetic material within a patient's cells to treat or prevent diseases. The increasing demand for gene therapies is fueled by advancements in delivery systems that enable the safe, efficient, and targeted delivery of genetic material into cells. Viral vector purification plays a vital role in enhancing gene therapies by ensuring that viral vectors are of high quality, safe, and biologically active. It improves the effectiveness of therapies by removing impurities and optimizing vector performance, leading to reliable and efficient treatment outcomes. For example, in December 2024, the American Society of Gene & Cell Therapy (ASGCT), a U.S.-based non-profit medical and scientific organization, reported that the Food and Drug Administration (FDA) approved six gene therapy products in 2023, up from five approvals in 2022. As such, the increasing demand for gene therapies is fueling the growth of the viral vector purification market.
Key players in the viral vector purification market are focusing on rapid, high-throughput analytical solutions, such as macro mass photometry platforms. These platforms use light scattering to measure the size and mass of viral particles, allowing for precise differentiation between empty and full capsids and detection of degraded particles within minutes. For example, in November 2023, Refeyn Ltd., a UK-based biotechnology company, launched KaritroMP, a macro mass photometry platform designed to analyze adenovirus and lentivirus vectors in just six minutes. This platform offers semi-automated sample processing for up to 13 samples, provides high reproducibility for quality control, and can detect subtle variations in particle mass to optimize purification processes. The launch enhances the capabilities of viral vector manufacturers by enabling faster and more accurate assessment of vector quality, while also streamlining workflow efficiency and reducing time and resources spent on vector characterization and purification.
In September 2025, Thermo Fisher Scientific Inc., a U.S.-based scientific instruments and life sciences company, acquired Solventum's purification and filtration business for approximately $4.0 billion. With this acquisition, Thermo Fisher strengthens its bioprocessing portfolio by integrating Solventum's advanced purification and filtration technologies, which will enhance the quality, efficiency, and end-to-end capabilities of viral vector manufacturing workflows, both upstream and downstream. Solventum Corporation, a U.S.-based healthcare company, specializes in bioprocessing filtration and purification solutions, including products that support viral vector purification.
Major companies operating in the viral vector purification market are Merck KGaA, Thermo Fisher Scientific Inc., Lonza Group AG, FUJIFILM Diosynth Biotechnologies, Danaher Corporation, Sartorius AG, Agilent Technologies Inc., Eurofins Scientific SE, Charles River Laboratories International Inc., Bio-Rad Laboratories Inc., AGC Biologics A/S, CoJourney, Takara Bio Inc., Miltenyi Biotec B.V. & Co. KG, Oxford Biomedica PLC, Revvity Inc., Applied Biological Materials Inc. (ABM), Minapharm Pharmaceuticals, Batavia Biosciences B.V., Creative Biolabs Inc., Andelyn Biosciences Inc.
North America was the largest region in the viral vector purification market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in viral vector purification report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the viral vector purification market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The viral vector purification market includes revenues earned by entities through process development, analytical testing, formulation development, chromatography, ultrafiltration, precipitation, quality control, viral clearance validation, scale-up optimization, and stability testing. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Viral Vector Purification Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on viral vector purification market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Where is the largest and fastest growing market for viral vector purification ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The viral vector purification market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.