EV-Based Liquid Biopsy Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Offering, By Workflow, By Technology, By Sample Type, By End user, By Region and Competition, 2020-2030F

Description

The Global EV-Based Liquid Biopsy Market , valued at USD 91.12 Million in 2024, is projected to experience a CAGR of 9.74% to reach USD 159.14 Million by 2030. Extracellular vesicle (EV)-based liquid biopsy involves the non-invasive analysis of disease-specific biomarkers encapsulated within extracellular vesicles, such as exosomes, circulating in bodily fluids like blood or urine. These vesicles carry molecular cargoes including proteins, nucleic acids, and lipids, providing insights into the physiological and pathological state of originating cells. The market's expansion is significantly driven by the increasing global burden of chronic diseases, particularly cancer, and the rising demand for early, non-invasive diagnostic solutions. The inherent stability and abundance of EVs in biofluids, offering advantages over other circulating biomarkers, also act as key growth facilitators.

Market Overview
Forecast Period	2026-2030
Market Size 2024	USD 91.12 Million
Market Size 2030	USD 159.14 Million
CAGR 2025-2030	9.74%
Fastest Growing Segment	Kits & Assays
Largest Market	North America

Key Market Drivers

The escalating global cancer burden fundamentally drives the EV-based liquid biopsy market. Traditional diagnostic methods often face limitations in early detection and continuous monitoring, areas where the non-invasive nature of EV liquid biopsies offers significant advantages. As cancer incidence continues its upward trajectory, the urgency for advanced, accessible diagnostic tools intensifies. According to the International Agency for Research on Cancer (IARC), in 2022, there were close to 20 million new cases of cancer worldwide. This pervasive health crisis necessitates innovative solutions that can accurately identify malignancies at earlier stages and monitor treatment efficacy without the invasiveness of tissue biopsies, directly propelling the adoption and development of EV-based platforms.

Key Market Challenges

A substantial challenge impeding the growth of the Global EV-Based Liquid Biopsy Market is the ongoing technical complexity associated with isolating and comprehensively characterizing extracellular vesicles (EVs) from complex biofluids. This inherent variability in isolation methods and subsequent characterization protocols often leads to significant issues with reproducibility and consistent clinical validation. The lack of standardized procedures across different laboratories and platforms directly compromises the reliability of test results, creating skepticism among clinicians and delaying the widespread adoption of EV-based diagnostic solutions.

Key Market Trends

The emergence of novel EV biomarkers is significantly shaping the global EV-based liquid biopsy market by enhancing diagnostic precision and expanding application areas. Research into disease-specific cargo within extracellular vesicles, such as proteins and nucleic acids, is uncovering new targets for early detection and disease monitoring across various pathologies. This focus on biomarker discovery drives the development of more sensitive and specific diagnostic assays. According to the International Society for Extracellular Vesicles, its MISEV2023 guidelines, published in March 2024, garnered consensus from approximately 97% of surveyed members, reflecting a widespread scientific commitment to standardizing and advancing EV research which underpins biomarker identification. This collective effort is crucial for translating promising biomarker candidates into validated clinical tools. Furthermore, a review article in *Biology (Basel)* in September 2024, highlighted the therapeutic opportunity of tumor-derived extracellular vesicles, emphasizing their capacity to harbor cancer-derived cargo reflective of their cell-of-origin and their superior stability in blood for diagnostic and prognostic insights.

Key Market Players

Horiba Ltd.
Thermo Fisher Scientific, Inc.
Lonza Group AG
Takara Bio Inc.
Abcam plc
Qiagen N.V.
Malvern Panalytical Ltd.
Revvity, Inc. (PerkinElmer, Inc)
Norgen Biotek Corp.
Bio-Techne Corporation

Report Scope:

In this report, the Global EV-Based Liquid Biopsy Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

EV-Based Liquid Biopsy Market , By Offering:

Kits & Assays
Services
Instruments

EV-Based Liquid Biopsy Market , By Workflow:

Sample Preparation
Sequencing
Data Analysis

EV-Based Liquid Biopsy Market , By Technology:

Isolation Technologies
Analysis Technologies

EV-Based Liquid Biopsy Market , By Sample Type:

Blood
Urine
Saliva
Others

EV-Based Liquid Biopsy Market , By End User:

Academic and Research Institutes
Pharmaceutical & Biotechnology Companies
Clinical Laboratories

EV-Based Liquid Biopsy Market , By Region:

North America
- United States
- Canada
- Mexico
Europe
- France
- United Kingdom
- Italy
- Germany
- Spain
Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
South America
- Brazil
- Argentina
- Colombia
Middle East & Africa
- South Africa
- Saudi Arabia
- UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies presents in the Global EV-Based Liquid Biopsy Market .

Available Customizations:

Global EV-Based Liquid Biopsy Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

1. Product Overview

1.1. Market Definition
1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations

2. Research Methodology

2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations

3. Executive Summary

3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global EV-Based Liquid Biopsy Market Outlook

5.1. Market Size & Forecast
- 5.1.1. By Value
5.2. Market Share & Forecast
- 5.2.1. By Offering (Kits & Assays, Services, Instruments)
- 5.2.2. By Workflow (Sample Preparation, Sequencing, Data Analysis)
- 5.2.3. By Technology (Isolation Technologies, Analysis Technologies)
- 5.2.4. By Sample Type (Blood, Urine, Saliva, Others)
- 5.2.5. By End User (Academic and Research Institutes, Pharmaceutical & Biotechnology Companies, Clinical Laboratories)
- 5.2.6. By Region
- 5.2.7. By Company (2024)
5.3. Market Map

6. North America EV-Based Liquid Biopsy Market Outlook

6.1. Market Size & Forecast
- 6.1.1. By Value
6.2. Market Share & Forecast
- 6.2.1. By Offering
- 6.2.2. By Workflow
- 6.2.3. By Technology
- 6.2.4. By Sample Type
- 6.2.5. By End User
- 6.2.6. By Country
6.3. North America: Country Analysis
- 6.3.1. United States EV-Based Liquid Biopsy Market Outlook
  - 6.3.1.1. Market Size & Forecast
    - 6.3.1.1.1. By Value
  - 6.3.1.2. Market Share & Forecast
    - 6.3.1.2.1. By Offering
    - 6.3.1.2.2. By Workflow
    - 6.3.1.2.3. By Technology
    - 6.3.1.2.4. By Sample Type
    - 6.3.1.2.5. By End User
- 6.3.2. Canada EV-Based Liquid Biopsy Market Outlook
  - 6.3.2.1. Market Size & Forecast
    - 6.3.2.1.1. By Value
  - 6.3.2.2. Market Share & Forecast
    - 6.3.2.2.1. By Offering
    - 6.3.2.2.2. By Workflow
    - 6.3.2.2.3. By Technology
    - 6.3.2.2.4. By Sample Type
    - 6.3.2.2.5. By End User
- 6.3.3. Mexico EV-Based Liquid Biopsy Market Outlook
  - 6.3.3.1. Market Size & Forecast
    - 6.3.3.1.1. By Value
  - 6.3.3.2. Market Share & Forecast
    - 6.3.3.2.1. By Offering
    - 6.3.3.2.2. By Workflow
    - 6.3.3.2.3. By Technology
    - 6.3.3.2.4. By Sample Type
    - 6.3.3.2.5. By End User

7. Europe EV-Based Liquid Biopsy Market Outlook

7.1. Market Size & Forecast
- 7.1.1. By Value
7.2. Market Share & Forecast
- 7.2.1. By Offering
- 7.2.2. By Workflow
- 7.2.3. By Technology
- 7.2.4. By Sample Type
- 7.2.5. By End User
- 7.2.6. By Country
7.3. Europe: Country Analysis
- 7.3.1. Germany EV-Based Liquid Biopsy Market Outlook
  - 7.3.1.1. Market Size & Forecast
    - 7.3.1.1.1. By Value
  - 7.3.1.2. Market Share & Forecast
    - 7.3.1.2.1. By Offering
    - 7.3.1.2.2. By Workflow
    - 7.3.1.2.3. By Technology
    - 7.3.1.2.4. By Sample Type
    - 7.3.1.2.5. By End User
- 7.3.2. France EV-Based Liquid Biopsy Market Outlook
  - 7.3.2.1. Market Size & Forecast
    - 7.3.2.1.1. By Value
  - 7.3.2.2. Market Share & Forecast
    - 7.3.2.2.1. By Offering
    - 7.3.2.2.2. By Workflow
    - 7.3.2.2.3. By Technology
    - 7.3.2.2.4. By Sample Type
    - 7.3.2.2.5. By End User
- 7.3.3. United Kingdom EV-Based Liquid Biopsy Market Outlook
  - 7.3.3.1. Market Size & Forecast
    - 7.3.3.1.1. By Value
  - 7.3.3.2. Market Share & Forecast
    - 7.3.3.2.1. By Offering
    - 7.3.3.2.2. By Workflow
    - 7.3.3.2.3. By Technology
    - 7.3.3.2.4. By Sample Type
    - 7.3.3.2.5. By End User
- 7.3.4. Italy EV-Based Liquid Biopsy Market Outlook
  - 7.3.4.1. Market Size & Forecast
    - 7.3.4.1.1. By Value
  - 7.3.4.2. Market Share & Forecast
    - 7.3.4.2.1. By Offering
    - 7.3.4.2.2. By Workflow
    - 7.3.4.2.3. By Technology
    - 7.3.4.2.4. By Sample Type
    - 7.3.4.2.5. By End User
- 7.3.5. Spain EV-Based Liquid Biopsy Market Outlook
  - 7.3.5.1. Market Size & Forecast
    - 7.3.5.1.1. By Value
  - 7.3.5.2. Market Share & Forecast
    - 7.3.5.2.1. By Offering
    - 7.3.5.2.2. By Workflow
    - 7.3.5.2.3. By Technology
    - 7.3.5.2.4. By Sample Type
    - 7.3.5.2.5. By End User

8. Asia Pacific EV-Based Liquid Biopsy Market Outlook

8.1. Market Size & Forecast
- 8.1.1. By Value
8.2. Market Share & Forecast
- 8.2.1. By Offering
- 8.2.2. By Workflow
- 8.2.3. By Technology
- 8.2.4. By Sample Type
- 8.2.5. By End User
- 8.2.6. By Country
8.3. Asia Pacific: Country Analysis
- 8.3.1. China EV-Based Liquid Biopsy Market Outlook
  - 8.3.1.1. Market Size & Forecast
    - 8.3.1.1.1. By Value
  - 8.3.1.2. Market Share & Forecast
    - 8.3.1.2.1. By Offering
    - 8.3.1.2.2. By Workflow
    - 8.3.1.2.3. By Technology
    - 8.3.1.2.4. By Sample Type
    - 8.3.1.2.5. By End User
- 8.3.2. India EV-Based Liquid Biopsy Market Outlook
  - 8.3.2.1. Market Size & Forecast
    - 8.3.2.1.1. By Value
  - 8.3.2.2. Market Share & Forecast
    - 8.3.2.2.1. By Offering
    - 8.3.2.2.2. By Workflow
    - 8.3.2.2.3. By Technology
    - 8.3.2.2.4. By Sample Type
    - 8.3.2.2.5. By End User
- 8.3.3. Japan EV-Based Liquid Biopsy Market Outlook
  - 8.3.3.1. Market Size & Forecast
    - 8.3.3.1.1. By Value
  - 8.3.3.2. Market Share & Forecast
    - 8.3.3.2.1. By Offering
    - 8.3.3.2.2. By Workflow
    - 8.3.3.2.3. By Technology
    - 8.3.3.2.4. By Sample Type
    - 8.3.3.2.5. By End User
- 8.3.4. South Korea EV-Based Liquid Biopsy Market Outlook
  - 8.3.4.1. Market Size & Forecast
    - 8.3.4.1.1. By Value
  - 8.3.4.2. Market Share & Forecast
    - 8.3.4.2.1. By Offering
    - 8.3.4.2.2. By Workflow
    - 8.3.4.2.3. By Technology
    - 8.3.4.2.4. By Sample Type
    - 8.3.4.2.5. By End User
- 8.3.5. Australia EV-Based Liquid Biopsy Market Outlook
  - 8.3.5.1. Market Size & Forecast
    - 8.3.5.1.1. By Value
  - 8.3.5.2. Market Share & Forecast
    - 8.3.5.2.1. By Offering
    - 8.3.5.2.2. By Workflow
    - 8.3.5.2.3. By Technology
    - 8.3.5.2.4. By Sample Type
    - 8.3.5.2.5. By End User

9. Middle East & Africa EV-Based Liquid Biopsy Market Outlook

9.1. Market Size & Forecast
- 9.1.1. By Value
9.2. Market Share & Forecast
- 9.2.1. By Offering
- 9.2.2. By Workflow
- 9.2.3. By Technology
- 9.2.4. By Sample Type
- 9.2.5. By End User
- 9.2.6. By Country
9.3. Middle East & Africa: Country Analysis
- 9.3.1. Saudi Arabia EV-Based Liquid Biopsy Market Outlook
  - 9.3.1.1. Market Size & Forecast
    - 9.3.1.1.1. By Value
  - 9.3.1.2. Market Share & Forecast
    - 9.3.1.2.1. By Offering
    - 9.3.1.2.2. By Workflow
    - 9.3.1.2.3. By Technology
    - 9.3.1.2.4. By Sample Type
    - 9.3.1.2.5. By End User
- 9.3.2. UAE EV-Based Liquid Biopsy Market Outlook
  - 9.3.2.1. Market Size & Forecast
    - 9.3.2.1.1. By Value
  - 9.3.2.2. Market Share & Forecast
    - 9.3.2.2.1. By Offering
    - 9.3.2.2.2. By Workflow
    - 9.3.2.2.3. By Technology
    - 9.3.2.2.4. By Sample Type
    - 9.3.2.2.5. By End User
- 9.3.3. South Africa EV-Based Liquid Biopsy Market Outlook
  - 9.3.3.1. Market Size & Forecast
    - 9.3.3.1.1. By Value
  - 9.3.3.2. Market Share & Forecast
    - 9.3.3.2.1. By Offering
    - 9.3.3.2.2. By Workflow
    - 9.3.3.2.3. By Technology
    - 9.3.3.2.4. By Sample Type
    - 9.3.3.2.5. By End User

10. South America EV-Based Liquid Biopsy Market Outlook

10.1. Market Size & Forecast
- 10.1.1. By Value
10.2. Market Share & Forecast
- 10.2.1. By Offering
- 10.2.2. By Workflow
- 10.2.3. By Technology
- 10.2.4. By Sample Type
- 10.2.5. By End User
- 10.2.6. By Country
10.3. South America: Country Analysis
- 10.3.1. Brazil EV-Based Liquid Biopsy Market Outlook
  - 10.3.1.1. Market Size & Forecast
    - 10.3.1.1.1. By Value
  - 10.3.1.2. Market Share & Forecast
    - 10.3.1.2.1. By Offering
    - 10.3.1.2.2. By Workflow
    - 10.3.1.2.3. By Technology
    - 10.3.1.2.4. By Sample Type
    - 10.3.1.2.5. By End User
- 10.3.2. Colombia EV-Based Liquid Biopsy Market Outlook
  - 10.3.2.1. Market Size & Forecast
    - 10.3.2.1.1. By Value
  - 10.3.2.2. Market Share & Forecast
    - 10.3.2.2.1. By Offering
    - 10.3.2.2.2. By Workflow
    - 10.3.2.2.3. By Technology
    - 10.3.2.2.4. By Sample Type
    - 10.3.2.2.5. By End User
- 10.3.3. Argentina EV-Based Liquid Biopsy Market Outlook
  - 10.3.3.1. Market Size & Forecast
    - 10.3.3.1.1. By Value
  - 10.3.3.2. Market Share & Forecast
    - 10.3.3.2.1. By Offering
    - 10.3.3.2.2. By Workflow
    - 10.3.3.2.3. By Technology
    - 10.3.3.2.4. By Sample Type
    - 10.3.3.2.5. By End User

11. Market Dynamics

11.1. Drivers
11.2. Challenges

12. Market Trends & Developments

12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments

13. Global EV-Based Liquid Biopsy Market : SWOT Analysis

14. Porter's Five Forces Analysis

14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products

15. Competitive Landscape

15.1. Horiba Ltd.
- 15.1.1. Business Overview
- 15.1.2. Products & Services
- 15.1.3. Recent Developments
- 15.1.4. Key Personnel
- 15.1.5. SWOT Analysis
15.2. Thermo Fisher Scientific, Inc.
15.3. Lonza Group AG
15.4. Takara Bio Inc.
15.5. Abcam plc
15.6. Qiagen N.V.
15.7. Malvern Panalytical Ltd.
15.8. Revvity, Inc. (PerkinElmer, Inc)
15.9. Norgen Biotek Corp.
15.10. Bio-Techne Corporation